Initial orthostatic hypotension at high altitude

High Altitude Medicine and Biology

Volumn 11, Issue 2, 2010, Pages 163-167

  Thomas, Kate N ^a   Burgess, Keith R ^b   Basnyat, Rishi ^c,d   Lucas, Samuel J E ^a   Cotter, James D ^a   Fan, Jui Lin ^a   Peebles, Karen C ^a   Lucas, Rebekah A I ^a   Ainslie, Philip N ^e  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF SYDNEY   (Australia)

^c NEPAL INTERNATIONAL CLINIC   (Nepal)

^d Himalayan Rescue Association   (Nepal)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALTITUDE; ALTITUDE DISEASE; ARTICLE; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; CARDIOVASCULAR RESPONSE; COMPARATIVE STUDY; DIASTOLIC BLOOD PRESSURE; DOPPLER ECHOGRAPHY; END TIDAL CARBON DIOXIDE TENSION; FEMALE; FINOMETER; FLOWMETER; HEART RATE; HUMAN; HUMAN EXPERIMENT; HYPOTHESIS; MALE; MEAN ARTERIAL PRESSURE; MEASUREMENT; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; ORTHOSTATIC HYPOTENSION; OXYGEN TENSION; PRIORITY JOURNAL; REST; SEA LEVEL; STANDING; SUPINE POSITION; SYSTOLIC BLOOD PRESSURE; VOLUNTEER; ACCLIMATIZATION; ADAPTATION; BLOOD PRESSURE; BODY POSTURE; BRAIN CIRCULATION; COMPLICATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HEMODYNAMICS; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNCOPE; YOUNG ADULT;

ACCLIMATIZATION; ADAPTATION, PHYSIOLOGICAL; ADULT; ALTITUDE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CEREBROVASCULAR CIRCULATION; HEMODYNAMICS; HUMANS; HYPOTENSION, ORTHOSTATIC; MALE; OXYGEN CONSUMPTION; POSTURE; SYNCOPE; YOUNG ADULT;

EID: 77954911190     PISSN: 15270297     EISSN: None     Source Type: Journal    
DOI: 10.1089/ham.2009.1056     Document Type: Article

References (29)

1. Ainslie P.N., Burgess K., Subedi P. and Burgess K.R. (2007). Alterations in cerebral dynamics at high altitude following partial acclimatization in humans: wakefulness and sleep. J. Appl. Physiol. 102:658-664.
2. 2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation. Am. J. Physiol-Regulatory Integrative and Comparative Physiology 296:R1473-1495.
3. Basnyat B., Wu T. and Gertsch J.H. (2004). Neurological conditions at altitude that fall outside the usual definition of altitude sickness. High Alt. Med. Biol. 5:171-179.
4. Blaber A.P., Hartley T. and Pretorius P.J. (2003). Effect of acute exposure to 3660 m altitude on orthostatic responses and tolerance. J. Appl. Physiol. 95:591-601.
5. Brignole M., Alboni P., Benditt D.G., Bergfeldt L., Blanc J.J., Bloch Thomsen P.E., van Dijk J.G., Fitzpatrick A., Hohnloser S., Janousek J., Kapoor W., Kenny R.A., Kulakowski P., Masotti G., Moya A., Raviele A., Sutton R., Theodorakis G., Ungar A. and Wieling W. (2004). Guidelines on management (diagnosis and treatment) of syncope-update 2004. Europace 6:467-537.
6. Franco Folino A. (2007). Cerebral autoregulation and syncope. Progr. Cardiovasc. Dis. 50:49-80.
7. Freitas J., Costa O., Carvalho M.J. and Falcao de Freitas A. (1996). High altitude-related neurocardiogenic syncope. Am. J. Cardiol. 77:1021.
8. 1-adrenergic blockade at high altitude. Aviation Space Environ. Med. 1075-1080.
9. Hainsworth R., Drinkhill M.J. and Rivera-Chira M. (2007). The autonomic nervous system at high altitude. Clin. Autonomic Res. 17:13-19.
10. Hansen J. and Sander M. (2003). Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxia. J. Physiol. 546:921-929.
11. Jansen G.F., Krins A., Basnyat B., Bosch A. and Odoom J.A. (2000). Cerebral autoregulation in subjects adapted and not adapted to high altitude. Stroke 31:2314-2318.
12. Kapoor W.N., Smith M.A. and Miller N.L. (1994). Upright tilt testing in evaluating syncope: a comprehensive literature review. Am. J. Med. 97:78-88.
13. Levine B.D., Zhang R. and Roach R.C. (1999). Dynamic cerebral autoregulation at high altitude. Adv. Exper. Med. Biol. 474:319-322.
14. Malhorta M.S. and Murthy W.S. (1977). Changes in orthostatic tolerance in man at an altitude of 3500m. Aviation Space Environ. Med. 125-128.
15. Malhorta M.S., Slevamurthy W. and Purkayastha S.S. (1976). Respnse of the autonomic nervous system during acclimatisation to high altitude in man. Aviation Space Environ. Med. 1076-1079.
16. Mytton O.T., Simpson A., Thompson A.A., Oram R.A., Darowski A., Yu L.M., Collier D.J. and Pollard A.J. (2008). Manual assessment of the initial fall in blood pressure after orthostatic challenge at high altitude. Wilderness Environ. Med. 19:225-232.
17. Nicholas R., O'Meara P.D. and Calonge N. (1992). Is syncope related to moderate altitude exposure? JAMA 268:904-906.
18. Ogoh S., Brothers R.M., Eubank W.L. and Raven P.B. (2008). Autonomic neural control of the cerebral vasculature: acute hypotension. Stroke 39:1979-1987.
19. Perrill C.V. (1993). High-altitude syncope: history repeats itself. JAMA 269:587.
20. Roach R.C., Bartsch P., Hackett P.H. and Oelz O. (1993). The Lake Louise acute mountain sickness scoring system. In Hy-poxia and Molecular Medicine., Sutton Jr, Coates J and Houston C, eds., pp. 272-274. Queen City, Burlington, VT.
21. Roy S.B., Guleria J.S., Khanna P.K., Talwar J.R., Manchanda S.C., Pande J.N., Kaushik V.S., Subba P.S. and Wood J.E. (1968). Immediate circulatory response to high altitude hypoxia in man. Nature 217:1177-1178.
22. Sagawa S., Torii R., Nagaya K., Wada F., Endo Y. and Shiraki K. (1997). Carotid baroreflex control of heart rate during acute exposure to simulated altitudes of 3,800m and 4,300 m. Am. J. Physiol. 273:R1219-1223.
23. Sampson J.B., Cymerman A., Burse R.L., Maher J.T. and Rock P.B. (1983). Procedures for the measurement of acute mountain sickness. Aviat Space Environ Med 54: 1063-1073.
24. Secher N.H., Seifert T. and Van Lieshout J.J. (2008). Cerebral blood flow and metabolism during exercise: implications for fatigue. J.Appl. Physiol. 104:306-314.
25. Severinghaus J.W., Chiodi H., Eger E.I. 2nd, Brandstater B. and Hornbein T.F. (1966). Cerebral blood flow in man at high altitude. Role of cerebrospinal fluid pH in normalization of flow in chronic hypocapnia. Circ. Res. 19:274-282.
26. Thomas K.N., Cotter J.D., Galvin S.D., Williams M.J., Willie C.K. and Ainslie P.N. (2009). Initial Orthostatic Hypotension Is Unrelated To Orthostatic Tolerance In Healthy Young Subjects. J.Appl. Physiol. 107:506-517.
27. Van Lieshout J.J., Wieling W., Karemaker J.M. and Secher N.H. (2003). Syncope, cerebral perfusion, and oxygenation. J.Appl. Physiol. 94:833-848.
28. Wieling W., Krediet C.T., van Dijk N., Linzer M. and Tscha-kovsky M.E. (2007). Initial orthostatic hypotension: review of a forgotten condition. Clin. Sci. 112:157-165.
29. Wieling W. and Van Lieshout J.J. (1997). Maintenance of postural normotension in humans. In Clinical Autonomic Disorders, pp. 73-82. Lippincott-Raven, Philadelphia.