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Volumn 88, Issue 4, 2010, Pages 603-609

The inhibitory effect of celecoxib on mouse hepatoma H22 cell line on the arachidonic acid metabolic pathway 1

Author keywords

Arachidonic acid; Celecoxib; Cyclooxygenase 2; Cytosolic phospholipase A2; Prostaglandin E2

Indexed keywords

ARACHIDONIC ACIDS; CELECOXIB; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE; PROSTAGLANDINE;

EID: 77954910392     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O09-184     Document Type: Article
Times cited : (13)

References (39)
  • 1
    • 0034905269 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398
    • PMID:11350912
    • Bae, S.H., Jung, E.S., Park, Y.M., Kim, B.S., Kim, B.K., Kim, D.G., and Ryu, W.S. 2001. Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398. Clin. Cancer Res. 7(5): 1410-1418. PMID:11350912.
    • (2001) Clin. Cancer Res , vol.7 , Issue.5 , pp. 1410-1418
    • Bae, S.H.1    Jung, E.S.2    Park, Y.M.3    Kim, B.S.4    Kim, B.K.5    Kim, D.G.6    Ryu, W.S.7
  • 2
    • 0032948111 scopus 로고    scopus 로고
    • Regulation and inhibition of phospholipase A2
    • doi:10.1146/annurev. pharmtox.39.1.175. PMID:10331081
    • Balsinde, J., Balboa, M.A., Insel, P.A., and Dennis, E.A. 1999. Regulation and inhibition of phospholipase A2. Annu. Rev. Pharmacol. Toxicol. 39(1): 175-189. doi:10.1146/annurev. pharmtox.39.1.175. PMID:10331081.
    • (1999) Annu. Rev. Pharmacol. Toxicol , vol.39 , Issue.1 , pp. 175-189
    • Balsinde, J.1    Balboa, M.A.2    Insel, P.A.3    Dennis, E.A.4
  • 3
    • 0042131693 scopus 로고    scopus 로고
    • Epidemiology of non-steroidal anti-inflammatory drugs and cancer
    • doi:10.1159/ 000071364. PMID:12795046
    • Baron, J.A. 2003. Epidemiology of non-steroidal anti-inflammatory drugs and cancer. Prog. Exp. Tumor Res. 37: 1-24.doi:10.1159/ 000071364. PMID:12795046.
    • (2003) Prog. Exp. Tumor Res , vol.37 , pp. 1-24
    • Baron, J.A.1
  • 4
    • 34047161489 scopus 로고    scopus 로고
    • R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells
    • doi:10.1016/j.jhep.2006.11.017. PMID: 17275129
    • Behari, J., Zeng, G., Otruba, W., Thompson, M.D., Muller, P., Micsenyi, A., et al. 2007. R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells. J. Hepatol. 46(5): 849-857. doi:10.1016/j.jhep.2006.11.017. PMID: 17275129.
    • (2007) J. Hepatol , vol.46 , Issue.5 , pp. 849-857
    • Behari, J.1    Zeng, G.2    Otruba, W.3    Thompson, M.D.4    Muller, P.5    Micsenyi, A.6
  • 5
    • 45949111775 scopus 로고    scopus 로고
    • Cancer chemoprevention: A summary of the current evidence
    • B 3B, PMID:18630472
    • Bonovas, S., Tsantes, A., Drosos, T., and Sitaras, N.M. 2008. Cancer chemoprevention: a summary of the current evidence. Anticancer Res. 28(3B 3B): 1857-1866. PMID:18630472.
    • (2008) Anticancer Res , vol.28 , Issue.3 , pp. 1857-1866
    • Bonovas, S.1    Tsantes, A.2    Drosos, T.3    Sitaras, N.M.4
  • 6
    • 0036100517 scopus 로고    scopus 로고
    • NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines
    • doi:10.1002/ijc.10409. PMID:12115513
    • Cheng, J., Imanishi, H., Amuro, Y., and Hada, T. 2002. NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines. Int. J. Cancer, 99(5): 755-761.doi:10.1002/ijc.10409. PMID:12115513.
    • (2002) Int. J. Cancer , vol.99 , Issue.5 , pp. 755-761
    • Cheng, J.1    Imanishi, H.2    Amuro, Y.3    Hada, T.4
  • 7
    • 28144445331 scopus 로고    scopus 로고
    • In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells
    • doi:10.1158/1078-0432.CCR-05-1044.PMID:16299255
    • Cui, W., Yu, C.H., and Hu, K.Q. 2005. In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells. Clin. Cancer Res. 11(22): 8213-8221. doi:10.1158/1078-0432.CCR-05-1044.PMID:16299255.
    • (2005) Clin. Cancer Res , vol.11 , Issue.22 , pp. 8213-8221
    • Cui, W.1    Yu, C.H.2    Hu, K.Q.3
  • 8
    • 52649131493 scopus 로고    scopus 로고
    • In-vivo effects and mechanisms of celecoxib-reduced growth of cyclooxygenase-2 (COX-2)-expressing versus COX-2-deleted human HCC xenografts in nude mice
    • doi:10.1097/CAD.0b013e32830ef8ca. PMID:18766003
    • Cui, W., Hu, S.X., Tang, Z.Y., and Hu, K.Q. 2008. In-vivo effects and mechanisms of celecoxib-reduced growth of cyclooxygenase-2 (COX-2)-expressing versus COX-2-deleted human HCC xenografts in nude mice. Anticancer Drugs, 19(9): 891-897. doi:10.1097/CAD.0b013e32830ef8ca. PMID:18766003.
    • (2008) Anticancer Drugs , vol.19 , Issue.9 , pp. 891-897
    • Cui, W.1    Hu, S.X.2    Tang, Z.Y.3    Hu, K.Q.4
  • 9
    • 0344406231 scopus 로고    scopus 로고
    • The role of cyclooxy-genase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines
    • doi:10.1093/carcin/24.3.385. PMID:12663496
    • Dommels, Y.E., Haring, M.M., Keestra, N.G., Alink, G.M., van Bladeren, P.J., and van Ommen, B. 2003. The role of cyclooxy-genase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE(2) synthesis and cytotoxicity in human colorectal carcinoma cell lines. Carcinogenesis, 24(3): 385-392. doi:10.1093/carcin/24.3.385. PMID:12663496.
    • (2003) Carcinogenesis , vol.24 , Issue.3 , pp. 385-392
    • Dommels, Y.E.1    Haring, M.M.2    Keestra, N.G.3    Alink, G.M.4    van Bladeren, P.J.5    van Ommen, B.6
  • 10
    • 0034471496 scopus 로고    scopus 로고
    • Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia
    • doi:10.1080/10408360091174286. PMID:11078056
    • Fosslien, E. 2000. Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia. Crit. Rev. Clin. Lab. Sci. 37(5): 431-502. doi:10.1080/10408360091174286. PMID:11078056.
    • (2000) Crit. Rev. Clin. Lab. Sci , vol.37 , Issue.5 , pp. 431-502
    • Fosslien, E.1
  • 11
    • 33745238704 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2)-independent anticarcinogenic ef-fects of selective COX-2 inhibitors
    • PMID:16757698
    • Grosch, S., Maier, T.J., Schiffmann, S., and Geisslinger, G. 2006. Cyclooxygenase-2 (COX-2)-independent anticarcinogenic ef-fects of selective COX-2 inhibitors. J. Natl. Cancer Inst. 98(11): 736-747. PMID:16757698.
    • (2006) J. Natl. Cancer Inst , vol.98 , Issue.11 , pp. 736-747
    • Grosch, S.1    Maier, T.J.2    Schiffmann, S.3    Geisslinger, G.4
  • 12
    • 0035496616 scopus 로고    scopus 로고
    • Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
    • doi:10.1038/35094017. PMID:11900248
    • Gupta, R.A., and Dubois, R.N. 2001. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat. Rev. Cancer, 1(1): 11-21. doi:10.1038/35094017. PMID:11900248.
    • (2001) Nat. Rev. Cancer , vol.1 , Issue.1 , pp. 11-21
    • Gupta, R.A.1    Dubois, R.N.2
  • 13
    • 0036083383 scopus 로고    scopus 로고
    • 85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells
    • PMID:11897617
    • Han, C., Demetris, A.J., Michalopoulos, G., Shelhamer, J.H., and Wu, T. 2002. 85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells. Am. J. Physiol. Gastrointest. Liver Physiol. 282(4): 586-597. PMID:11897617.
    • (2002) Am. J. Physiol. Gastrointest. Liver Physiol , vol.282 , Issue.4 , pp. 586-597
    • Han, C.1    Demetris, A.J.2    Michalopoulos, G.3    Shelhamer, J.H.4    Wu, T.5
  • 14
    • 33644898889 scopus 로고    scopus 로고
    • Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine ki-nases and enhances invasiveness in human hepatocellular carcinoma cells
    • doi:10.1002/jcp. 20560. PMID:16331686
    • Han, C., Michalopoulos, G.K., and Wu, T. 2006. Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine ki-nases and enhances invasiveness in human hepatocellular carcinoma cells. J. Cell. Physiol. 207(1): 261-270.doi:10.1002/jcp. 20560. PMID:16331686.
    • (2006) J. Cell. Physiol , vol.207 , Issue.1 , pp. 261-270
    • Han, C.1    Michalopoulos, G.K.2    Wu, T.3
  • 16
    • 0023901609 scopus 로고
    • Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia
    • doi:10.1002/1097-0142(19880501) 61:9<1813::AID-CNCR2820610915>3.0.CO;2-U. PMID:2833340
    • Ikeda, T., Tozuka, S., Hasumura, Y., and Takeuchi, J. 1988. Prostaglandin-E-producing hepatocellular carcinoma with hypercalcemia. Cancer, 61(9): 1813-1814. doi:10.1002/1097-0142(19880501) 61:9<1813::AID-CNCR2820610915>3.0.CO;2-U. PMID:2833340.
    • (1988) Cancer , vol.61 , Issue.9 , pp. 1813-1814
    • Ikeda, T.1    Tozuka, S.2    Hasumura, Y.3    Takeuchi, J.4
  • 17
    • 24344444134 scopus 로고    scopus 로고
    • Non-COX-2 targets and cancer: Expanding the molecular target repertoire of chemoprevention
    • doi:10.1016/j.bcp.2005. 05.004. PMID:15949789
    • Kashfi, K., and Rigas, B. 2005. Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention. Biochem. Pharmacol. 70(7): 969-986. doi:10.1016/j.bcp.2005. 05.004. PMID:15949789.
    • (2005) Biochem. Pharmacol , vol.70 , Issue.7 , pp. 969-986
    • Kashfi, K.1    Rigas, B.2
  • 18
    • 0036788542 scopus 로고    scopus 로고
    • Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells
    • PMID:12297835
    • Kern, M.A., Schubert, D., Sahi, D., Schoneweiss, M.M., Moll, I., Haugg, A.M., et al. 2002. Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells. Hepatology, 36(4 Pt 1): 885-894. PMID:12297835.
    • (2002) Hepatology , vol.36 , Issue.1-4 , pp. 885-894
    • Kern, M.A.1    Schubert, D.2    Sahi, D.3    Schoneweiss, M.M.4    Moll, I.5    Haugg, A.M.6
  • 19
    • 44649133144 scopus 로고    scopus 로고
    • Effect of serum starvation and chemical inhibitors on cell cycle synchronization of canine dermal fibroblasts
    • doi:10.1016/j.theriogenology.2008.02.015. PMID:18423836
    • Khammanit, R., Chantakru, S., Kitiyanant, Y., and Saikhun, J. 2008. Effect of serum starvation and chemical inhibitors on cell cycle synchronization of canine dermal fibroblasts. Theriogenology, 70(1): 27-34. doi:10.1016/j.theriogenology.2008.02.015. PMID:18423836.
    • (2008) Theriogenology , vol.70 , Issue.1 , pp. 27-34
    • Khammanit, R.1    Chantakru, S.2    Kitiyanant, Y.3    Saikhun, J.4
  • 20
    • 0032978469 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation
    • doi:10.1002/hep.510290355. PMID:10051469
    • Koga, H., Sakisaka, S., Ohishi, M., Kawaguchi, T., Taniguchi, E., Sasatomi, K., et al. 1999. Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation. Hepatology, 29(3): 688-696. doi:10.1002/hep.510290355. PMID:10051469.
    • (1999) Hepatology , vol.29 , Issue.3 , pp. 688-696
    • Koga, H.1    Sakisaka, S.2    Ohishi, M.3    Kawaguchi, T.4    Taniguchi, E.5    Sasatomi, K.6
  • 21
    • 17044453428 scopus 로고    scopus 로고
    • Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma
    • PMID:10632332
    • Kondo, M., Yamamoto, H., Nagano, H., Okami, J., Ito, Y., Shimizu, J., et al. 1999. Increased expression of COX-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma. Clin. Cancer Res. 5(12): 4005-4012. PMID:10632332.
    • (1999) Clin. Cancer Res , vol.5 , Issue.12 , pp. 4005-4012
    • Kondo, M.1    Yamamoto, H.2    Nagano, H.3    Okami, J.4    Ito, Y.5    Shimizu, J.6
  • 22
    • 64549144677 scopus 로고    scopus 로고
    • Cytotoxicity induced by inhibition of thioredoxin reductases via multiple signaling pathways: Role of cytosolic phospholipase A(2)alpha-dependent and - independent release of arachidonic acid
    • doi:10.1002/jcp.21703. PMID:19170071
    • Kurosawa, T., Nakamura, H., Yamaura, E., Fujino, H., Matsuzawa, Y., Kawashima, T., and Murayama, T. 2009. Cytotoxicity induced by inhibition of thioredoxin reductases via multiple signaling pathways: role of cytosolic phospholipase A(2)alpha-dependent and - independent release of arachidonic acid. J. Cell. Physiol. 219(3): 606-616. doi:10.1002/jcp.21703. PMID:19170071.
    • (2009) J. Cell. Physiol , vol.219 , Issue.3 , pp. 606-616
    • Kurosawa, T.1    Nakamura, H.2    Yamaura, E.3    Fujino, H.4    Matsuzawa, Y.5    Kawashima, T.6    Murayama, T.7
  • 23
    • 0041822007 scopus 로고    scopus 로고
    • Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-induced apoptosis
    • doi:10.1053/jhep.2003.50380. PMID:12939602
    • Leng, J., Han, C., Demetris, A.J., Michalopoulos, G.K., and Wu, T. 2003. Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis. Hepatology, 38(3): 756-768. doi:10.1053/jhep.2003.50380. PMID:12939602.
    • (2003) Hepatology , vol.38 , Issue.3 , pp. 756-768
    • Leng, J.1    Han, C.2    Demetris, A.J.3    Michalopoulos, G.K.4    Wu, T.5
  • 24
    • 34548593179 scopus 로고    scopus 로고
    • Up-regulation of cPLA(2) gene expression in astrocytes by all three conventional anti-bipolar drugs is drug-specific and enzyme-specific
    • doi:10.1007/s00213-007-0853-5. PMID:17594078
    • Li, B., Gu, L., Zhang, H., Huang, J., Chen, Y., Hertz, L., and Peng, L. 2007. Up-regulation of cPLA(2) gene expression in astrocytes by all three conventional anti-bipolar drugs is drug-specific and enzyme-specific. Psychopharmacology (Berl.), 194(3): 333-345. doi:10.1007/s00213-007-0853-5. PMID:17594078.
    • (2007) Psychopharmacology (Berl.) , vol.194 , Issue.3 , pp. 333-345
    • Li, B.1    Gu, L.2    Zhang, H.3    Huang, J.4    Chen, Y.5    Hertz, L.6    Peng, L.7
  • 25
    • 29544438981 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 in human HepG2, Bel-7402 and SMMC-7721 hepatoma cell lines and mechanism of cyclooxygenase-2 selective inhibitor celecoxib-induced cell growth inhibition and apoptosis
    • PMID:16419156
    • Liu, N.B., Peng, T., Pan, C., Yao, Y.Y., Shen, B., and Leng, J. 2005. Overexpression of cyclooxygenase-2 in human HepG2, Bel-7402 and SMMC-7721 hepatoma cell lines and mechanism of cyclooxygenase-2 selective inhibitor celecoxib-induced cell growth inhibition and apoptosis. World J. Gastroenterol. 11(40): 6281-6287. PMID:16419156.
    • (2005) World. J. Gastroenterol , vol.11 , Issue.40 , pp. 6281-6287
    • Liu, N.B.1    Peng, T.2    Pan, C.3    Yao, Y.Y.4    Shen, B.5    Leng, J.6
  • 26
    • 1642407595 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2)-dependent and -indepen-dent anticarcinogenic effects of celecoxib in human colon carcinoma cells
    • doi:10. 1016/j.bcp.2003.12.014. PMID:15041464
    • Maier, T.J., Schilling, K., Schmidt, R., Geisslinger, G., and Grosch, S. 2004. Cyclooxygenase-2 (COX-2)-dependent and -indepen-dent anticarcinogenic effects of celecoxib in human colon carcinoma cells. Biochem. Pharmacol. 67(8): 1469-1478. doi:10. 1016/j.bcp.2003.12.014. PMID:15041464.
    • (2004) Biochem. Pharmacol , vol.67 , Issue.8 , pp. 1469-1478
    • Maier, T.J.1    Schilling, K.2    Schmidt, R.3    Geisslinger, G.4    Grosch, S.5
  • 27
    • 0036213281 scopus 로고    scopus 로고
    • Phospholipase A2
    • PMID:11872155
    • Murakami, M., and Kudo, I. 2002. Phospholipase A2. J. Biochem. 131(3): 285-292. PMID:11872155.
    • (2002) J. Biochem , vol.131 , Issue.3 , pp. 285-292
    • Murakami, M.1    Kudo, I.2
  • 28
    • 33750964503 scopus 로고    scopus 로고
    • Roles of cPLA2alpha and arachidonic acid in cancer
    • PMID:17052951
    • Nakanishi, M., and Rosenberg, D.W. 2006. Roles of cPLA2alpha and arachidonic acid in cancer. Biochim. Biophys. Acta, 1761(11): 1335-1343. PMID:17052951.
    • (2006) Biochim. Biophys. Acta , vol.1761 , Issue.11 , pp. 1335-1343
    • Nakanishi, M.1    Rosenberg, D.W.2
  • 29
    • 0035403764 scopus 로고    scopus 로고
    • Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB
    • PMID:11427506
    • Niederberger, E., Tegeder, I., Vetter, G., Schmidtko, A., Schmidt, H., Euchenhofer, C., et al. 2001. Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB. FASEB J. 15(9): 1622-1624. PMID:11427506.
    • (2001) FASEB J , vol.15 , Issue.9 , pp. 1622-1624
    • Niederberger, E.1    Tegeder, I.2    Vetter, G.3    Schmidtko, A.4    Schmidt, H.5    Euchenhofer, C.6
  • 30
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • doi:10.1002/ijc.1440. PMID:11668491
    • Parkin, D.M., Bray, F., Ferlay, J., and Pisani, P. 2001. Estimating the world cancer burden: Globocan 2000. Int. J. Cancer, 94(2): 153-156. doi:10.1002/ijc.1440. PMID:11668491.
    • (2001) Int. J. Cancer , vol.94 , Issue.2 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 31
    • 36448957271 scopus 로고    scopus 로고
    • Direct non-cyclooxygenase-2 targets of celecoxib and their potential relevance for cancer therapy
    • doi:10.1038/sj.bjc.6604049. PMID: 17955049
    • Schonthal, A.H. 2007a. Direct non-cyclooxygenase-2 targets of celecoxib and their potential relevance for cancer therapy. Br. J. Cancer, 97(11): 1465-1468. doi:10.1038/sj.bjc.6604049. PMID: 17955049.
    • (2007) Br. J. Cancer , vol.97 , Issue.11 , pp. 1465-1468
    • Schonthal, A.H.1
  • 32
    • 34347251961 scopus 로고    scopus 로고
    • Induction of apoptosis by celecoxib in cell culture: An uncertain role for cyclooxygenase-2
    • doi:10.1158/0008-5472. CAN-06-3414. PMID:17545641 Author Reply
    • Schonthal, A.H. 2007b. Induction of apoptosis by celecoxib in cell culture: an uncertain role for cyclooxygenase-2. Cancer Res. 67(11): 5575-5576, author reply 5576. doi:10.1158/0008-5472. CAN-06-3414. PMID:17545641.
    • (2007) Cancer Res , vol.67 , Issue.11 , pp. 5575-5576
    • Schonthal, A.H.1
  • 33
    • 0035853767 scopus 로고    scopus 로고
    • Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling
    • doi:10.1074/jbc.M010603200. PMID:11134037
    • Scorrano, L., Penzo, D., Petronilli, V., Pagano, F., and Bernardi, P. 2001. Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling. J. Biol. Chem. 276(15): 12035-12040. doi:10.1074/jbc.M010603200. PMID:11134037.
    • (2001) J. Biol. Chem. , vol.276 , Issue.15 , pp. 12035-12040
    • Scorrano, L.1    Penzo, D.2    Petronilli, V.3    Pagano, F.4    Bernardi, P.5
  • 34
    • 58849093275 scopus 로고    scopus 로고
    • Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners
    • doi:10.1124/mol.108.051128. PMID:18945820
    • Shin, S.M., and Kim, S.G. 2009. Inhibition of arachidonic acid and iron-induced mitochondrial dysfunction and apoptosis by oltipraz and novel 1,2-dithiole-3-thione congeners. Mol. Pharmacol. 75(1): 242-253. doi:10.1124/mol.108.051128. PMID:18945820.
    • (2009) Mol. Pharmacol , vol.75 , Issue.1 , pp. 242-253
    • Shin, S.M.1    Kim, S.G.2
  • 35
    • 0033063736 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in hepatocellular carcinoma
    • PMID:10228831
    • Shiota, G., Okubo, M., Noumi, T., Noguchi, N., Oyama, K., Takano, Y., et al. 1999. Cyclooxygenase-2 expression in hepatocellular carcinoma. Hepatogastroenterology, 46(25): 407-412. PMID:10228831.
    • (1999) Hepatogastroenterology , vol.46 , Issue.25 , pp. 407-412
    • Shiota, G.1    Okubo, M.2    Noumi, T.3    Noguchi, N.4    Oyama, K.5    Takano, Y.6
  • 36
    • 0034971264 scopus 로고    scopus 로고
    • Why there are two cyclooxygenase isozymes
    • doi:10.1172/JCI13271. PMID:11413152
    • Smith, W.L., and Langenbach, R. 2001. Why there are two cyclooxygenase isozymes. J. Clin. Invest. 107(12): 1491-1495. doi:10.1172/JCI13271. PMID:11413152.
    • (2001) J. Clin. Invest , vol.107 , Issue.12 , pp. 1491-1495
    • Smith, W.L.1    Langenbach, R.2
  • 37
    • 0035242430 scopus 로고    scopus 로고
    • Free fatty acid effects on mitochondrial permeability: An overview
    • doi:10.1006/abbi.2000.2195. PMID:11361000
    • Sultan, A., and Sokolove, P.M. 2001. Free fatty acid effects on mitochondrial permeability: an overview. Arch. Biochem. Biophys. 386(1): 52-61. doi:10.1006/abbi.2000.2195. PMID:11361000.
    • (2001) Arch. Biochem. Biophys , vol.386 , Issue.1 , pp. 52-61
    • Sultan, A.1    Sokolove, P.M.2
  • 39
    • 31544468915 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in hepatocellular carcinoma
    • doi:10.1016/j.ctrv.2005.10.004. PMID:16337744
    • Wu, T. 2006. Cyclooxygenase-2 in hepatocellular carcinoma. Cancer Treat. Rev. 32(1): 28-44. doi:10.1016/j.ctrv.2005.10.004. PMID:16337744.
    • (2006) Cancer Treat. Rev , vol.32 , Issue.1 , pp. 28-44
    • Wu, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.