Factor V leiden mutation in Behcet's disease and the relationship with clinical manifestations

Tehran University Medical Journal

Volumn 68, Issue 2, 2010, Pages 103-109

  Mowla, Karim ^a   Zakerkish, Mehrnoosh ^a   Samarbafzadeh, Alireza ^b   Aleali, Armaghan Moravej ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Behcet's disease; Factor V leiden; Mutation

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN;

ARTICLE; BEHCET DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; FEMALE; GENETIC ASSOCIATION; HUMAN; IRAN; IRIDOCYCLITIS; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; POINT MUTATION; POLYMERASE CHAIN REACTION; RETINA VASCULITIS; RISK FACTOR; STROKE; THROMBOPHLEBITIS;

EID: 77954865956     PISSN: 16831764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Sakane T, Takeno M, Suzuki N, Inaba G. Behçet's disease. N Engl J Med 1999;341(17):1284-91.
2. Yazici H, Yurdakul S, Hamuryudan V. Behçet disease. Curr Opin Rheumatol 2001;13(1):18-22.
3. Davatchi F, Sharam F, Akbarian M, Gharibdoost F, Nadji A, Chams C, et al. Behcet's Disease-Analysis of 3443 cases. APLAR J Rheumatol 1997;1:2-5.
4. Lane DA, Mannucci PM, Bauer KA, et al, Inherited thrombophilia: part 1. thromb Haemost 1996;76:651-62.
5. Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994;369(6475):64-7.
6. Svensson PJ, Dahlbäck B. Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 1994;330(8):517-22.
7. Arabic source
8. Davatchi F, Shahram F, Akbarian M, Epidemiology of Behcet's Disease in Iran. APLAR Rheumatol 1992:95-8.
9. Ateş A, Düzgün N, Ulu A, Tiryaki AO, Akar N. Factor V gene (1691A and 4070G) and prothrombin gene 20210A mutations in patients with Behçet's disease. Pathophysiol Haemost Thromb 2003;33(3):157-63.
10. Gül A, Ozbek U, Oztürk C, Inanç M, Koniçe M, Ozçelik T. Coagulation factor V gene mutation increases the risk of venous thrombosis in behçet's disease. Br J Rheumatol 1996;35(11):1178-80.
11. Mammo L, Al-Dalaan A, Bahabri SS, Saour JN. Association of factor V Leiden with Behçet's disease. J Rheumatol 1997;24(11):2196-8.
12. Mehmet S, Kahraman T, Suleyman O, Eren E. Factor V Leiden mutation in Behcet's disease. 8th Internation congress on Behcet's disease. Italy: Regsio Emilia, 1998.
13. Oner AF, Gürgey A, Gürler A, Mesci L. Factor V Leiden mutation in patients with Behçet's disease. J Rheumatol 1998;25(3):496-8.
14. Verity DH, Vaughan RW, Madanat W, Kondeatis E, Zureikat H, Fayyad F, et al. Factor V Leiden mutation is associated with ocular involvement in Behçet disease. Am J Ophthalmol 1999;128(3):352-6.
15. Toydemir PB, Elhan AH, Tükün A, Toydemir R, Gürler A, Tüzüner A, et al. Effects of factor V gene G1691A, methylenetetrahydrofolate reductase gene C677T, and prothombin gene G20210A mutations on deep venous thrombogenesis in Behçet's disease. J Rheumatol 2000;27(12):2849-54.
16. Espinosa G, Font J, Tàssies D, Vidaller A, Deulofeu R, López-Soto A, et al. Vascular involvement in Behçet's disease: relation with thrombophilic factors, coagulation activation, and thrombomodulin. Am J Med 2002;112(1):37-43.
17. Silingardi M, Salvarani C, Boiardi L, Accardo P, Iorio A, Olivieri I, et al. Factor V Leiden and prothrombin gene G20210A mutations in Italian patients with Behçet's disease and deep vein thrombosis. Arthritis Rheum 2004;51(2):177-83.
18. Batioǧlu F, Atmaca LS, Karabulut HG, Beyza Sayin D. Factor V Leiden and prothrombin gene G20210A mutations in ocular Behçet disease. Acta Ophthalmol Scand 2003;81(3):283-5.