Factor V Leiden and prothrombin gene G20210A mutations in ocular Behçet disease

Acta Ophthalmologica Scandinavica

Volumn 81, Issue 3, 2003, Pages 283-285

  Batioǧlu, Figen ^a   Atmaca, Leyla S ^a   Karabulut, Halil Gürhan ^a   Sayin, Derya Beyza ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Beh et's disease; Factor V Leiden mutation; Procoagulant factors; Prothrombin G20210A mutation; Vascular occlusion

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; PROTHROMBIN;

ADULT; ARTICLE; BEHCET DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANGIOGRAPHY; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; MALE; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETINA BLOOD VESSEL OCCLUSION; RISK FACTOR; TURKEY (REPUBLIC); VISUAL SYSTEM EXAMINATION;

ADOLESCENT; ADULT; BEHCET SYNDROME; DNA MUTATIONAL ANALYSIS; FACTOR V; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; MALE; MIDDLE AGED; POINT MUTATION; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PROTHROMBIN; RETINAL ARTERY OCCLUSION; RETINAL VEIN OCCLUSION; RISK FACTORS;

EID: 0037743910     PISSN: 13953907     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0420.2003.00068.x     Document Type: Article

References (21)

1. Akar N, Akar E, Dalgin G, Sözüöz A, Ömürlü K&Cin S (1997): Frequency of factor V (1691 GA) mutation in Turkish population. Thromb Haemost 78: 1527-1529.
2. Akar N, Misirlioglu M, Akar E, Avcu F, Yalçin A & Sözüöz A (1998): Prothrombin gene 20210 GA mutation in the Turkish population. Am J Hematol 58: 249.
3. Aydyntuo AO, Tokgöz G, D'Cruz DP et al. (1993): Antibodies to endothelial cells in patients with Behçet's disease. Clin Immunopathol 67: 157-162.
4. Behçet H (1937): Über rezidivierende, aphthöse, durch ein Virus verursachte Geschwure am Munde, am Auge und an Genitalien. Dermatol Wochenschr 105: 1152-1157.
5. Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, Jo Ronde H, van der Velden PA&Reitsma PH (1994): Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369: 64-67.
6. Cumming AM, Keeney S, Salden A, Bhavnani M, Shwe KH&Hay CRM (1997): The prothrombin gene G20210A variant: prevalence in a UK anticoagulant clinic population. Br J Haematol 98: 353-355.
7. Eller AW, Bontempo FA, Faruki H&Hassett AC (1998): Peripheral retinal neovascularization (Eales' disease) associated with the factor V Leiden mutation. Am J Ophthalmol 126: 146-149.
8. Greven CM&Wall AB (1997): Peripheral retinal neovascularization and retinal vascular occlusion associated with activated protein C resistance. Am J Ophthalmol 124: 687-689.
9. Gül A, Özbek U, Öztürk C, Inanç M, Koniçe M & Özçelik T (1996): Coagulation factor V gene mutation increases the risk of venous thrombosis in Behçet's disease. Br J Rheumatol 35: 1178-1180.
10. Gürgey A, Hiçsönmez G, Parlak H, Balta G & Çeliker A (1998): The prothrombin gene 2021OG-A mutation in Turkish patients with thrombosis. Am J Hematol 59: 179-180.
11. Gürgey A&Mesci L (1997): The prevalence of FV Leiden mutation in the Turkish population. Turk J Pediatr 39: 310-315.
12. Gürgey A, Mesci L, Renda Y, Olcay L, Koçak N&Erdem G (1996): Factor V Leiden mutation in children with thrombosis. Am J Hematol 53: 37-39.
13. Kalayci D, Gürgey A, Güven D, Parlak H&Hasiripi H (1999): Factor V Leiden and prothrombin 20210 A mutations in patients with central and branch retinal vein occlusion. Acta Ophthalmol Scand 77: 622-624.
14. Larsson J, Olafsdottir E&Bauer B (1996): Activated protein C resistance in young adults with central retinal vein occlusion. Br J Ophthalmol 80: 200-202.
15. Öner AF, Gürgey A, Gürler A&Mesci L (1998): Factor V Leiden mutation in patients with Behçet's disease. J Rheumatol 25: 496-498.
16. Poort SR, Rosendaal FR, Reitsma PH&Bertina RM (1996): A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88: 3698-3703.
17. Rees D, Cox M&Clegg J (1995): World distribution of factor V Leiden. Lancet 346: 1133-1134.
18. Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Eisenberg PR&Miletich JP (1995): Mutation in the gene coding for coagulation factor V, and the risk of myocardial infarction, stroke venous thrombosis in apparently healthy men. N Engl J Med 332: 912-917.
19. Talmon T, Scharf J, Mayer E, Lanir N, Miller B&Brenner B (1997): Retinal arterial occlusion in a child with factor V Leiden and thermolabile methylene tetralrydrofolate reductase mutations. Am J Ophthalmol 124: 689-691.
20. Tursen U, Kaya TI, Eskandari G, Gunduz O, Yazar M, Ikizoglu G & Atik U (2001): Association of factor V Leiden and prothrombin gene mutation with Behçet disease. Arch Dermatol Res 293: 537-539.
21. Verity DH, Vaughan RW, Madanat W et al. (1999): Factor V Leiden mutation is associated with ocular involvement in Behçet's disease. Am J Ophthalmol 128: 352-356.