-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005, 352:987-96.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
2
-
-
42349089115
-
Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients
-
Wolff JE, Berrak S, Koontz Webb SE. Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients. J Neurooncol 2008, 88:57-63.
-
(2008)
J Neurooncol
, vol.88
, pp. 57-63
-
-
Wolff, J.E.1
Berrak, S.2
Koontz Webb, S.E.3
-
3
-
-
0026468376
-
Identification of the cross-link between human O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea-treated DNA
-
Gonzaga PE, Potter PM, Niu TQ. Identification of the cross-link between human O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea-treated DNA. Cancer Res 1992, 52:6052-8.
-
(1992)
Cancer Res
, vol.52
, pp. 6052-6058
-
-
Gonzaga, P.E.1
Potter, P.M.2
Niu, T.Q.3
-
4
-
-
0034745978
-
Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide
-
Kokkinakis DM, Bocangel DB, Schold SC, Moschel RC, Pegg AE. Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide. Clin Cancer Res 2001, 7:421-8.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 421-428
-
-
Kokkinakis, D.M.1
Bocangel, D.B.2
Schold, S.C.3
Moschel, R.C.4
Pegg, A.E.5
-
5
-
-
0028980765
-
Contribution of O6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor derived cell lines
-
Bobola MS, Berger MS, Silber JR. Contribution of O6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor derived cell lines. Mol Carcinog 1995, 13:81-8.
-
(1995)
Mol Carcinog
, vol.13
, pp. 81-88
-
-
Bobola, M.S.1
Berger, M.S.2
Silber, J.R.3
-
6
-
-
34447314728
-
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
-
Kaina B, Christmann M, Naumann S, Roos WP. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents. DNA Repair (Amst) 2007, 6:1079-99.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 1079-1099
-
-
Kaina, B.1
Christmann, M.2
Naumann, S.3
Roos, W.P.4
-
7
-
-
0028988143
-
O6-methylguanine-DNA methyltransferase activity in breast and brain tumors
-
Preuss I, Eberhagen I, Haas S. O6-methylguanine-DNA methyltransferase activity in breast and brain tumors. Int J Cancer 1995, 61:321-6.
-
(1995)
Int J Cancer
, vol.61
, pp. 321-326
-
-
Preuss, I.1
Eberhagen, I.2
Haas, S.3
-
8
-
-
0036968081
-
Heterogeneity of O6-alkylguanine-DNA alkyltransferase activity in colorectal cancer: implications for treatment
-
Lees NP, Harrison KL, Hill E, Hall CN, Povey AC, Margison GP. Heterogeneity of O6-alkylguanine-DNA alkyltransferase activity in colorectal cancer: implications for treatment. Oncology 2002, 63:393-7.
-
(2002)
Oncology
, vol.63
, pp. 393-397
-
-
Lees, N.P.1
Harrison, K.L.2
Hill, E.3
Hall, C.N.4
Povey, A.C.5
Margison, G.P.6
-
9
-
-
37549042449
-
Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks
-
Batista LF, Roos WP, Christmann M, Menck CF, Kaina B. Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks. Cancer Res 2007, 67:11886-95.
-
(2007)
Cancer Res
, vol.67
, pp. 11886-11895
-
-
Batista, L.F.1
Roos, W.P.2
Christmann, M.3
Menck, C.F.4
Kaina, B.5
-
10
-
-
70349099568
-
DNA double-strand breaks: Their production, recognition, and repair in eukaryotes
-
Ohnishi T, Mori E, Takahashi A. DNA double-strand breaks: Their production, recognition, and repair in eukaryotes. Mutat Res 2009, 669:8-12.
-
(2009)
Mutat Res
, vol.669
, pp. 8-12
-
-
Ohnishi, T.1
Mori, E.2
Takahashi, A.3
-
11
-
-
10844286478
-
Evidence for the involvement of double-strand breaks in heat-induced cell killing
-
Takahashi A, Matsumoto H, Nagayama K. Evidence for the involvement of double-strand breaks in heat-induced cell killing. Cancer Res 2004, 64:8839-45.
-
(2004)
Cancer Res
, vol.64
, pp. 8839-8845
-
-
Takahashi, A.1
Matsumoto, H.2
Nagayama, K.3
-
12
-
-
68549134901
-
DNA ligase IV as a new molecular target for temozolomide
-
Kondo N, Takahashi A, Mori E. DNA ligase IV as a new molecular target for temozolomide. Biochem Biophys Res Commun 2009, 387:656-60.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, pp. 656-660
-
-
Kondo, N.1
Takahashi, A.2
Mori, E.3
-
13
-
-
33745553269
-
Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide
-
Tsaryk R, Fabian K, Thacker J, Kaina B. Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide. Cancer Lett 2006, 239:305-13.
-
(2006)
Cancer Lett
, vol.239
, pp. 305-313
-
-
Tsaryk, R.1
Fabian, K.2
Thacker, J.3
Kaina, B.4
-
14
-
-
29244435019
-
Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells
-
Nojima K, Hochegger H, Saberi A. Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res 2005, 65:11704-11.
-
(2005)
Cancer Res
, vol.65
, pp. 11704-11711
-
-
Nojima, K.1
Hochegger, H.2
Saberi, A.3
-
15
-
-
0036006173
-
O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy
-
Margison GP, Santibañez-Koref MF. O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy. Bioessays 2002, 24:255-66.
-
(2002)
Bioessays
, vol.24
, pp. 255-266
-
-
Margison, G.P.1
Santibañez-Koref, M.F.2
-
16
-
-
0035436539
-
Repair of DNA interstrand cross-links: molecular mechanisms and clinical relevance
-
McHugh PJ, Spanswick VJ, Hartley JA. Repair of DNA interstrand cross-links: molecular mechanisms and clinical relevance. Lancet Oncol 2001, 2:483-90.
-
(2001)
Lancet Oncol
, vol.2
, pp. 483-490
-
-
McHugh, P.J.1
Spanswick, V.J.2
Hartley, J.A.3
-
17
-
-
0042531939
-
Deficient regulation of DNA double-strand break repair in Fanconi anemia fibroblasts
-
Donahue SL, Lundberg R, Saplis R, Campbell C. Deficient regulation of DNA double-strand break repair in Fanconi anemia fibroblasts. J Biol Chem 2003, 278:29487-95.
-
(2003)
J Biol Chem
, vol.278
, pp. 29487-29495
-
-
Donahue, S.L.1
Lundberg, R.2
Saplis, R.3
Campbell, C.4
-
18
-
-
3142682325
-
HXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51
-
Shim KS, Schmutte C, Tombline G, Heinen CD, Fishel R. hXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51. J Biol Chem 2004, 279:30385-94.
-
(2004)
J Biol Chem
, vol.279
, pp. 30385-30394
-
-
Shim, K.S.1
Schmutte, C.2
Tombline, G.3
Heinen, C.D.4
Fishel, R.5
-
19
-
-
0033602450
-
Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation
-
Tan TL, Essers J, Citterio E. Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Curr Biol 1999, 9:325-8.
-
(1999)
Curr Biol
, vol.9
, pp. 325-328
-
-
Tan, T.L.1
Essers, J.2
Citterio, E.3
-
20
-
-
4544362838
-
The mechanism of non-homologous end-joining: a synopsis of synapsis
-
Weterings E, van Gent DC. The mechanism of non-homologous end-joining: a synopsis of synapsis. DNA Repair (Amst) 2004, 3:1425-35.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1425-1435
-
-
Weterings, E.1
van Gent, D.C.2
-
21
-
-
0025274315
-
A novel pathway of DNA end-to-end joining
-
Thode S, Schafer A, Pfeiffer P, Vielmetter W. A novel pathway of DNA end-to-end joining. Cell 1990, 60:921-8.
-
(1990)
Cell
, vol.60
, pp. 921-928
-
-
Thode, S.1
Schafer, A.2
Pfeiffer, P.3
Vielmetter, W.4
-
22
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998, 273:5858-68.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
23
-
-
26444553297
-
Does γH2AX foci formation depend on the presence of DNA double strand breaks?
-
Takahashi A, Ohnishi T. Does γH2AX foci formation depend on the presence of DNA double strand breaks? Cancer Lett 2005, 229:171-9.
-
(2005)
Cancer Lett
, vol.229
, pp. 171-179
-
-
Takahashi, A.1
Ohnishi, T.2
-
24
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
Ward IM, Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J Biol Chem 2001, 276:47759-62.
-
(2001)
J Biol Chem
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
25
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000, 10:886-95.
-
(2000)
Curr Biol
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
26
-
-
57349117060
-
DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus
-
Takahashi A, Yamakawa N, Kirita T. DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus. J Radiat Res (Tokyo) 2008, 49:645-52.
-
(2008)
J Radiat Res (Tokyo)
, vol.49
, pp. 645-652
-
-
Takahashi, A.1
Yamakawa, N.2
Kirita, T.3
-
27
-
-
0038813698
-
Induction of DNA replication-mediated double strand breaks by psoralen DNA interstrand cross-links
-
Bessho T. Induction of DNA replication-mediated double strand breaks by psoralen DNA interstrand cross-links. J Biol Chem 2003, 278:5250-4.
-
(2003)
J Biol Chem
, vol.278
, pp. 5250-5254
-
-
Bessho, T.1
-
28
-
-
33645105856
-
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells
-
Hermisson M, Klumpp A, Wick W. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J Neurochem 2006, 96:766-76.
-
(2006)
J Neurochem
, vol.96
, pp. 766-776
-
-
Hermisson, M.1
Klumpp, A.2
Wick, W.3
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