A sensitive electrochemical assay for early detection of HIv-1 protease using ferrocenepeptide conjugate/AU nanoparticle/single walled carbon nanotube modified electrode

Analytical Letters

Volumn 43, Issue 10-11, 2010, Pages 1680-1687

  Mahmoud, Khaled A ^a   Luong, John H T ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Electrochemistry; Ferrocene; Gold nanoparticle; Hiv 1; Pepstatin; Protease; Single walled carbon nanotube

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77954856822     PISSN: 00032719     EISSN: 1532236X     Source Type: Journal    
DOI: 10.1080/00032711003653924     Document Type: Article

References (19)

1. Amano, Y., and Q. Cheng. 2005. Detection of influenza virus: Traditional approaches and development of biosensors. Anal. Bioanal. Chem. 381: 156.
2. Ballagi-Pordany, B. S. 1993. Application of the polymerase chain reaction (PCR) in veterinary diagnostic virology. Vet. Res. Commun. 17: 55.
3. Dominguez, E. A., L. H. Taber, and R. B. Couch. 1993. Comparison of rapid diagnostic techniques for respiratory syncytial and influenza a virus respiratory infections in young children. J. Clin. Microbiol. 31: 2286.
4. Elfath, A. M. A., M. Elnifro, R. J. Cooper, and P. E. Klapper. 2000. Multiplex PCR: Optimization and application in diagnostic virology. Clin. Microbiol. Rev. 13: 559.
5. Hjelle, B., and M. Busch. 1989. Direct methods for detection of HIV-1 infection. Arch. Path. Lab. Med. 113: 975.
6. Iqbal, S. S., M. W. Mayo, J. G. Bruno, B. V. Bronk, C. A. Batt, and J. P. Chambers. 2000. A review of molecular recognition technologies for detection of biological threat agents. Biosens. Bioelectron. 15: 549.
7. Kerman, K., K. A. Mahmoud, and H.-B. Kraatz. 2007. An electrochemical approach for the detection of HIV-1 protease. Chem. Commun. 3829.
8. Kohl, N. E., E. A. Emini, W. A. Schleif, L. J. Davis, J. C. Heimbach, R. A. Dixon, E. M. Scolnick, and I. S. Sigal. 1988. Active human immunodeficiency virus protease is required for viral infectivity. Proc. Natl. Acad. Sci. USA 85: 4686.
9. Lennette, E. H., and T. F. Smith. 1999. Laboratory Diagnosis of Viral Infections, 3rd ed. New York: Marcel Dekker.
10. Mahmoud, K. A., S. Hrapovic, and J. H. T. Luong. 2008. Picomolar detection of protease using peptide/single walled carbon nanotube/gold nanoparticle-modified electrode. ACS Nano 2: 1051.
11. Mahmoud, K. A., and J. H. T. Luong. 2008. Impedance method for detecting HIV-1 protease and screening for its inhibitors using ferrocene-peptide conjugate/Au nanoparticle/singlewalled carbon nanotube modified electrode. Anal. Chem. 80: 7056.
12. Marie Louie, L. L., and A. E. Simor. 2000. The role of DNA amplification technology in the diagnosis of infectious diseases. CMAJ 63: 301.
13. McQuade, T. J., A. G. Tomasselli, L. Liu, B. Karacostas, B. Moss, T. K. Sawyer, R. L. Heinrikson, and W. G. Tarpley. 1990. A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation. Science 247: 454.
14. Niesters, H. G. M. 2004. Molecular and diagnostic clinical virology in real time. Clin. Microbiol. Infect. 10: 5.
15. Parekh, B. S., and J. S. McDougal. 2001. New approaches for detecting recent HIV-1 infection. AIDS Rev. 3: 183.
16. Pejcic, B., R. De Marco, and G. Parkinson. 2006. The role of biosensors in the detection of emerging infectious diseases. Analyst 131: 1079.
17. Seelmeier, S., H. Schmidt, V. Turk, and K. von der Helm. 1988. Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin. Proc. Natl. Acad. Sci.USA 85: 6612.
18. World Health Organization Report "Early Detection of HIV Infection" http://www.who.int/hiv/en/
19. Xu, Y., and H.-B. Kraatz. 2001. Efficient Synthesis of unsymmetrically disubstituted ferrocenes: Towards electrochemical dipeptide-Fc-biosensors. Tetrahedron Lett. 42: 2601