Common genetic variation, residential proximity to traffic exposure, and left ventricular mass: The multi-ethnic study of atherosclerosis

Environmental Health Perspectives

Volumn 118, Issue 7, 2010, Pages 962-969

  van Hee, Victor C ^a   Adar, Sara D ^a   Szpiro, Adam A ^a   Graham Barr, R ^b   Roux, Ana Diez ^c   Bluemke, David A ^d   Sheppard, Lianne ^a   Gill, Edward A ^a   Bahrami, Hossein ^e,f   Wassel, Christina ^g   Sale, Michele M ^h   Siscovick, David S ^a   Rotter, Jerome I ^h   Rich, Stephen S ⁱ   Kaufman, Joel D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Department of Medicine   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

^h CEDARS SINAI MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF VIRGINIA   (United States)

Author keywords

AGTR1; Air pollution; ALOX15; Cardiac MRI; Cardiac structure; Gene environment interactions; Left ventricular mass; Traffic

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTILIPEMIC AGENT; ARACHIDONATE 15 LIPOXYGENASE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLOOXYGENASE 2 INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENDOTHELIN 1; G PROTEIN COUPLED RECEPTOR KINASE 4; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN ENDOPEROXIDE; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 1; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN B; EXHAUST GAS;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR FUNCTION; ETHNICITY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HEART LEFT VENTRICLE MASS; HOMOZYGOSITY; HUMAN; HYPERTENSION; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; PRIORITY JOURNAL; RESIDENTIAL AREA; SINGLE NUCLEOTIDE POLYMORPHISM; TRAFFIC; AIR POLLUTION; CROSS-SECTIONAL STUDY; ENVIRONMENTAL EXPOSURE; EXHAUST GAS; GENETIC PREDISPOSITION; GENETICS; HYPERTROPHY, LEFT VENTRICULAR; MIDDLE AGED; PATHOLOGY; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AIR POLLUTION; CROSS-SECTIONAL STUDIES; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HAPLOTYPES; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; VEHICLE EMISSIONS;

EID: 77954835219     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0901535     Document Type: Article

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