메뉴 건너뛰기




Volumn 16, Issue 7, 2010, Pages 13-18

The effect of N-acetylcysteine on blood pressure and markers of cardiovascular risk in non-diabetic patients with chronic kidney disease: A placebo-cotrolled, randomized, cross-over study

Author keywords

Albuminuria; Blood pressure; Chronic kidney disease; Homocyteine; N acetylcysteine

Indexed keywords

ACC 600; ACETYLCYSTEINE; ANGIOTENSIN RECEPTOR ANTAGONIST; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HOMOCYSTEINE; HYDROCHLOROTHIAZIDE; PLACEBO; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; PROTEIN; SCAVENGER; SODIUM;

EID: 77954779155     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 0031759999 scopus 로고    scopus 로고
    • Cardiovascular disease and mortality in ESRD
    • Foley RN, Parfrey PS: Cardiovascular disease and mortality in ESRD. JNephrol, 1998; 11(5): 239-452.
    • (1998) JNephrol , vol.11 , Issue.5 , pp. 239-452
    • Foley, R.N.1    Parfrey, P.S.2
  • 2
    • 1942506539 scopus 로고    scopus 로고
    • Chronic kidney disease as arisk factor for cardiovascular disease and all-cause mortality: A pooledanalysis of community-based studies
    • Weiner DE, Tighiouart H, Amin MG et al: Chronic kidney disease as arisk factor for cardiovascular disease and all-cause mortality: a pooledanalysis of community-based studies. J Am Soc Nephrol, 2004; 15(5):1307-153.
    • (2004) J Am Soc Nephrol , vol.15 , Issue.5 , pp. 1307-1153
    • Weiner, D.E.1    Tighiouart, H.2    Amin, M.G.3
  • 3
    • 44749091021 scopus 로고    scopus 로고
    • Emerging cardiovascularrisk factors that account for a significant portion of attributable mortalityrisk in chronic kidney disease
    • Shishehbor MH, Oliveira LP, Lauer MS et al: Emerging cardiovascularrisk factors that account for a significant portion of attributable mortalityrisk in chronic kidney disease. Am J Cardiol 2008, 101(12): 1741-464.
    • (2008) Am J Cardiol , vol.101 , Issue.12 , pp. 1741-1464
    • Shishehbor, M.H.1    Oliveira, L.P.2    Lauer, M.S.3
  • 4
    • 49749125234 scopus 로고    scopus 로고
    • Triple Pharmacological Blockadeof the Renin-Angiotensin-Aldosterone System in Nondiabetic CKD: AnOpen-Label Crossover Randomized Controlled Trial
    • Tylicki L, Rutkowski P, Renke M et al: Triple Pharmacological Blockadeof the Renin-Angiotensin-Aldosterone System in Nondiabetic CKD: AnOpen-Label Crossover Randomized Controlled Trial. Am J Kidney Dis,2008; 52(3): 486-935.
    • (2008) Am J Kidney Dis , vol.52 , Issue.3 , pp. 486-935
    • Tylicki, L.1    Rutkowski, P.2    Renke, M.3
  • 5
    • 28444462925 scopus 로고    scopus 로고
    • Low-dose dual blockade of therenin-angiotensin system improves tubular status in non-diabetic proteinuricpatients
    • Renke M, Tylicki L, Rutkowski P et al: Low-dose dual blockade of therenin-angiotensin system improves tubular status in non-diabetic proteinuricpatients. Scand J Urol Nephrol, 2005; 39(6): 511-176.
    • (2005) Scand J Urol Nephrol , vol.39 , Issue.6 , pp. 511-176
    • Renke, M.1    Tylicki, L.2    Rutkowski, P.3
  • 6
    • 30044450372 scopus 로고    scopus 로고
    • Renal protective effects of the renin-angiotensin-aldosterone system blockade: From evidence-based approachto perspectives
    • Tylicki L, Larczynski W, Rutkowski B: Renal protective effects of the renin-angiotensin-aldosterone system blockade: from evidence-based approachto perspectives. Kidney Blood Press Res, 2005; 28: 230-427.
    • (2005) Kidney Blood Press Res , vol.28 , pp. 230-427
    • Tylicki, L.1    Larczynski, W.2    Rutkowski, B.3
  • 7
    • 0742323174 scopus 로고    scopus 로고
    • Low-dose dual blockade of therenin-angiotensin system in patients with primary glomerulonephritis
    • Rutkowski P, Tylicki L, Renke M et al: Low-dose dual blockade of therenin-angiotensin system in patients with primary glomerulonephritis. Am J Kidney Dis, 2004; 43(2): 260-688.
    • (2004) Am J Kidney Dis , vol.43 , Issue.2 , pp. 260-688
    • Rutkowski, P.1    Tylicki, L.2    Renke, M.3
  • 8
    • 0035901585 scopus 로고    scopus 로고
    • Renal insufficiency as a predictorof cardiovascular outcomes and the impact of ramipril: The HOPE randomizedtrial
    • Mann JF, Gerstein HC, Pogue J et al: Renal insufficiency as a predictorof cardiovascular outcomes and the impact of ramipril: the HOPE randomizedtrial. Ann Intern Med, 2001; 134(8): 629-369.
    • (2001) Ann Intern Med , vol.134 , Issue.8 , pp. 629-369
    • Mann, J.F.1    Gerstein, H.C.2    Pogue, J.3
  • 9
    • 0034079643 scopus 로고    scopus 로고
    • Cardiovascular disease and chronic renal disease:A new paradigm
    • Sarnak MJ, Levey AS: Cardiovascular disease and chronic renal disease:a new paradigm. Am J Kidney Dis, 2000; 35(4 Suppl.1): S117-3110.
    • (2000) Am J Kidney Dis , vol.35 , Issue.4 , pp. 117-3110
    • Sarnak, M.J.1    Levey, A.S.2
  • 10
    • 0032800789 scopus 로고    scopus 로고
    • Imbalance of oxidants and antioxidantsin haemodialysis patients
    • Canaud B, Cristol J, Morena M et al: Imbalance of oxidants and antioxidantsin haemodialysis patients. Blood Purif, 1999; 17(2-3): 99-10611.
    • (1999) Blood Purif , vol.17 , Issue.2-3 , pp. 99-10611
    • Canaud, B.1    Cristol, J.2    Morena, M.3
  • 11
    • 0036833743 scopus 로고    scopus 로고
    • The elephant inuremia: Oxidant stress as a unifying concept of cardiovascular diseasein uremia
    • Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM: The elephant inuremia: oxidant stress as a unifying concept of cardiovascular diseasein uremia. Kidney Int, 2002; 62(5): 1524-3812.
    • (2002) Kidney Int , vol.62 , Issue.5 , pp. 1524-3812
    • Himmelfarb, J.1    Stenvinkel, P.2    Ikizler, T.A.3    Hakim, R.M.4
  • 12
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: Oxidants and antioxidants
    • Sies H: Oxidative stress: oxidants and antioxidants. Exp Physiol, 1997;82(2): 291-9513.
    • (1997) Exp Physiol , vol.82 , Issue.2 , pp. 291-9513
    • Sies, H.1
  • 13
    • 0344826719 scopus 로고    scopus 로고
    • Antioxidants: A possible role in kidneyprotection
    • Tylicki L, Rutkowski B, Horl WH: Antioxidants: a possible role in kidneyprotection. Kidney Blood Press Res, 2003; 26(5-6): 303-1414.
    • (2003) Kidney Blood Press Res , vol.26 , Issue.5-6 , pp. 303-1414
    • Tylicki, L.1    Rutkowski, B.2    Horl, W.H.3
  • 14
    • 0024394697 scopus 로고
    • The antioxidant action ofN-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • Aruoma OI, Halliwell B, Hoey BM, Butler J: The antioxidant action ofN-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med, 1989; 6(6):593-9715.
    • (1989) Free Radic Biol Med , vol.6 , Issue.6 , pp. 593-9715
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 15
    • 33846820184 scopus 로고    scopus 로고
    • Antihypertensive mechanisms of chroniccaptopril or N-acetylcysteine treatment in L-NAME hypertensive rats
    • Zicha J, Dobesova Z, Kunes J: Antihypertensive mechanisms of chroniccaptopril or N-acetylcysteine treatment in L-NAME hypertensive rats. Hypertens Res, 2006; 29(12): 1021-2716.
    • (2006) Hypertens Res , vol.29 , Issue.12 , pp. 1021-2716
    • Zicha, J.1    Dobesova, Z.2    Kunes, J.3
  • 16
    • 22444448994 scopus 로고    scopus 로고
    • Chronic N-acetylcysteine administrationprevents development of hypertension in N(omega)-nitro-L-arginine methyl ester-treated rats: The role of reactive oxygen species
    • Rauchova H, Pechanova O, Kunes J et al: Chronic N-acetylcysteine administrationprevents development of hypertension in N(omega)-nitro-L-arginine methyl ester-treated rats: The role of reactive oxygen species. Hypertens Res, 2005; 28(5): 475-8217.
    • (2005) Hypertens Res , vol.28 , Issue.5 , pp. 475-8217
    • Rauchova, H.1    Pechanova, O.2    Kunes, J.3
  • 17
    • 33751009384 scopus 로고    scopus 로고
    • Oxidative stress is progressivelyenhanced with advancing stages of CKD
    • Dounousi E, Papavasiliou E, Makedou A et al: Oxidative stress is progressivelyenhanced with advancing stages of CKD. Am J Kidney Dis,2006; 48: 752-6018.
    • (2006) Am J Kidney Dis , vol.48 , pp. 752-6018
    • Dounousi, E.1    Papavasiliou, E.2    Makedou, A.3
  • 18
    • 76049118200 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic kidney disease
    • Hakim FA, Pflueger A: Role of oxidative stress in diabetic kidney disease. Med Sci Monit, 2010; 16(2): RA37-4819.
    • (2010) Med Sci Monit , vol.16 , Issue.2 , pp. 37-4819
    • Hakim, F.A.1    Pflueger, A.2
  • 19
    • 66849091772 scopus 로고    scopus 로고
    • Role of oxidative stress in contrast-induced acute kidney injury in diabetes mellitus
    • Pflueger A, Abramowitz D, Calvin AD: Role of oxidative stress in contrast-induced acute kidney injury in diabetes mellitus. Med Sci Monit,2009; 15(6): RA125-3620.
    • (2009) Med Sci Monit , vol.15 , Issue.6 , pp. 125-3620
    • Pflueger, A.1    Abramowitz, D.2    Calvin, A.D.3
  • 20
    • 0037839029 scopus 로고    scopus 로고
    • Glutathione antioxidantsystem as a marker of oxidative stress in chronic renal failure
    • Ceballos-Picot I, Witko-Sarsat V, Merad-Boudia M et al: Glutathione antioxidantsystem as a marker of oxidative stress in chronic renal failure. Free Radic Biol Med, 1996; 21(6): 845-5321.
    • (1996) Free Radic Biol Med , vol.21 , Issue.6 , pp. 845-5321
    • Ceballos-Picot, I.1    Witko-Sarsat, V.2    Merad-Boudia, M.3
  • 21
    • 0033806871 scopus 로고    scopus 로고
    • Blood glutathione and cysteine changesin cardiovascular disease
    • Mills BJ, Weiss MM, Lang CA et al: Blood glutathione and cysteine changesin cardiovascular disease. J Lab Clin Med, 2000; 135(5): 396-40122.
    • (2000) J Lab Clin Med , vol.135 , Issue.5 , pp. 396-40122
    • Mills, B.J.1    Weiss, M.M.2    Lang, C.A.3
  • 22
    • 0027494532 scopus 로고
    • N-acetylcysteine inhibitsangiotensin converting enzyme in vivo
    • Boesgaard S, Aldershvile J, Poulsen HE et al: N-acetylcysteine inhibitsangiotensin converting enzyme in vivo. J Pharmacol Exp Ther, 1993;265(3): 1239-4423.
    • (1993) J Pharmacol Exp Ther , vol.265 , Issue.3 , pp. 1239-4423
    • Boesgaard, S.1    Aldershvile, J.2    Poulsen, H.E.3
  • 23
    • 48349130188 scopus 로고    scopus 로고
    • Effects of N-Acetylcysteine onAngiotensin-Converting Enzyme Plasma Activity in Patients with ChronicKidney Diseases
    • Tylicki L, Renke M, Rutkowski P et al: Effects of N-Acetylcysteine onAngiotensin-Converting Enzyme Plasma Activity in Patients with ChronicKidney Diseases. Blood Purif, 2008; 26(4): 35424.
    • (2008) Blood Purif , vol.26 , Issue.4 , pp. 35424
    • Tylicki, L.1    Renke, M.2    Rutkowski, P.3
  • 24
    • 0031737982 scopus 로고    scopus 로고
    • Cytotoxicity of advancedglycation endproducts is mediated by oxidative stress
    • Loske C, Neumann A, Cunningham AM et al: Cytotoxicity of advancedglycation endproducts is mediated by oxidative stress. J Neural Transm,1998; 105(8-9): 1005-1525.
    • (1998) J Neural Transm , vol.105 , Issue.8-9 , pp. 1005-1525
    • Loske, C.1    Neumann, A.2    Cunningham, A.M.3
  • 25
    • 33750271298 scopus 로고    scopus 로고
    • N-Acetylcysteine improves renal dysfunction, ameliorates kidney damage and decreases blood pressure insalt-sensitive hypertension
    • Tian N, Rose RA, Jordan S et al: N-Acetylcysteine improves renal dysfunction, ameliorates kidney damage and decreases blood pressure insalt-sensitive hypertension. J Hypertens, 2006; 24(11): 2263-7026.
    • (2006) J Hypertens , vol.24 , Issue.11 , pp. 2263-7026
    • Tian, N.1    Rose, R.A.2    Jordan, S.3
  • 26
    • 33645499898 scopus 로고    scopus 로고
    • Prognostic importance of ambulatory bloodpressure recordings in patients with chronic kidney disease
    • Agarwal R, Andersen MJ: Prognostic importance of ambulatory bloodpressure recordings in patients with chronic kidney disease. Kidney Int,2006; 69(7): 1175-8027.
    • (2006) Kidney Int , vol.69 , Issue.7 , pp. 1175-8027
    • Agarwal, R.1    Andersen, M.J.2
  • 27
    • 48649103801 scopus 로고    scopus 로고
    • Long-term N-acetylcysteine andL-arginine administration reduces endothelial activation and systolicblood pressure in hypertensive patients with type 2 diabetes
    • Martina V, Masha A, Gigliardi V et al: Long-term N-acetylcysteine andL-arginine administration reduces endothelial activation and systolicblood pressure in hypertensive patients with type 2 diabetes. DiabetesCare, 2008; 31: 940-4428.
    • (2008) DiabetesCare , vol.31 , pp. 940-4428
    • Martina, V.1    Masha, A.2    Gigliardi, V.3
  • 28
    • 0025804983 scopus 로고
    • Endothelium-derived relaxing and contracting factors
    • Rubanyi G: Endothelium-derived relaxing and contracting factors. JCell Biochem, 1991; 47: 27-3629.
    • (1991) JCell Biochem , vol.47 , pp. 27-3629
    • Rubanyi, G.1
  • 29
    • 34248368431 scopus 로고    scopus 로고
    • Low-grade albuminuria andcardiovascular risk: What is the evidence?
    • Schmieder R, Schrader J, Zidek W et al: Low-grade albuminuria andcardiovascular risk: what is the evidence? Clin res Cardiol, 2007; 96:247-5730.
    • (2007) Clin Res Cardiol , vol.96 , pp. 247-5730
    • Schmieder, R.1    Schrader, J.2    Zidek, W.3
  • 30
    • 0035948631 scopus 로고    scopus 로고
    • HOPE Study Investigators. Albuminuriaand risk of cardiovascular events, death, and heart failure in diabeticand nondiabetic individuals
    • Gerstein H, Mann J, Yi Q et al: HOPE Study Investigators. Albuminuriaand risk of cardiovascular events, death, and heart failure in diabeticand nondiabetic individuals. JAMA, 2001; 286: 421-2631.
    • (2001) JAMA , vol.286 , pp. 421-2631
    • Gerstein, H.1    Mann, J.2    Yi, Q.3
  • 31
    • 32144458041 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine onradiocontrast nephropathy in rats
    • Yenicerioglu Y, Yilmaz O, Sarioglu S et al: Effects of N-acetylcysteine onradiocontrast nephropathy in rats. Scand J Urol Nephrol, 2006; 40(1):63-6932.
    • (2006) Scand J Urol Nephrol , vol.40 , Issue.1 , pp. 63-6932
    • Yenicerioglu, Y.1    Yilmaz, O.2    Sarioglu, S.3
  • 32
    • 34548819086 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on endothelialdysfunction in dialysis patients
    • Sahin G, Yalcin AU, Akcar N: Effect of N-acetylcysteine on endothelialdysfunction in dialysis patients. Blood Purif, 2007; 25(4): 309-1533.
    • (2007) Blood Purif , vol.25 , Issue.4 , pp. 309-1533
    • Sahin, G.1    Yalcin, A.U.2    Akcar, N.3
  • 33
    • 0035171760 scopus 로고    scopus 로고
    • N-acetylcysteine improves coronaryand peripheral vascular function
    • Andrews N, Prasad A, Quyyumi A: N-acetylcysteine improves coronaryand peripheral vascular function. J Am Coll Cardiol, 2001; 37: 117-2334.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 117-2334
    • Andrews, N.1    Prasad, A.2    Quyyumi, A.3
  • 34
    • 0035145860 scopus 로고    scopus 로고
    • N-acetylcysteine attenuatesTNF-alpha-induced p38 MAP kinase activation and p38 MAP kinasemediatedIL-8 production by human pulmonary vascular endothelialcells
    • Hashimoto S, Gon Y, Matsumoto K et al: N-acetylcysteine attenuatesTNF-alpha-induced p38 MAP kinase activation and p38 MAP kinasemediatedIL-8 production by human pulmonary vascular endothelialcells. Br J Pharmacol, 2001; 132: 270-7635.
    • (2001) Br J Pharmacol , vol.132 , pp. 270-7635
    • Hashimoto, S.1    Gon, Y.2    Matsumoto, K.3
  • 35
    • 0037465546 scopus 로고    scopus 로고
    • The antioxidant acetylcysteinereduces cardiovascular events in patients with end-stage renal failure:A randomized, controlled trial
    • Tepel M, van der Giet M, Statz M et al: The antioxidant acetylcysteinereduces cardiovascular events in patients with end-stage renal failure:a randomized, controlled trial. Circulation, 2003; 107(7): 992-9536.
    • (2003) Circulation , vol.107 , Issue.7 , pp. 992-9536
    • Tepel, M.1    van der Giet, M.2    Statz, M.3
  • 36
    • 4644237693 scopus 로고    scopus 로고
    • A randomized controlled trialof intravenous N-acetylcysteine for the prevention of contrast-inducednephropathy after cardiac catheterization: Lack of effect
    • Webb JG, Pate GE, Humphries KH et al: A randomized controlled trialof intravenous N-acetylcysteine for the prevention of contrast-inducednephropathy after cardiac catheterization: lack of effect. Am Heart J,2004; 148(3): 422-2937.
    • (2004) Am Heart J , vol.148 , Issue.3 , pp. 422-2937
    • Webb, J.G.1    Pate, G.E.2    Humphries, K.H.3
  • 37
    • 34250800967 scopus 로고    scopus 로고
    • N-Acetylcysteine Does NotImprove the Endothelial and Smooth Musele Function in the HumanSaphenous Vein
    • Sharif M, Bayraktutan U, Young I, Soong C: N-Acetylcysteine Does NotImprove the Endothelial and Smooth Musele Function in the HumanSaphenous Vein. Vasc Endovasc Surg, 2007; 41: 239-4538.
    • (2007) Vasc Endovasc Surg , vol.41 , pp. 239-4538
    • Sharif, M.1    Bayraktutan, U.2    Young, I.3    Soong, C.4
  • 38
    • 5344252997 scopus 로고    scopus 로고
    • N-acetylcysteine reduces contrast-associated nephropathy but not clinical events during long-termfollow-up
    • Miner SE, Dzavik V, Nguyen-Ho P et al: N-acetylcysteine reduces contrast-associated nephropathy but not clinical events during long-termfollow-up. Am Heart J, 2004; 148(4): 690-9539.
    • (2004) Am Heart J , vol.148 , Issue.4 , pp. 690-9539
    • Miner, S.E.1    Dzavik, V.2    Nguyen-Ho, P.3
  • 39
    • 19044376964 scopus 로고    scopus 로고
    • Effects of N-acetylcysteine on microalbuminuriaand organ failure in acute severe sepsis: Results of a pilotstudy
    • Spapen H, Diltoer M, Nguyen D et al: Effects of N-acetylcysteine on microalbuminuriaand organ failure in acute severe sepsis: results of a pilotstudy. Chest, 2005; 127: 1413-1940.
    • (2005) Chest , vol.127 , pp. 1413-1940
    • Spapen, H.1    Diltoer, M.2    Nguyen, D.3
  • 40
    • 0024512008 scopus 로고
    • Effect of N-acetylcysteineon plasma cysteine and glutathione following paracetamol administration
    • Burgunder JM, Varriale A, Lauterburg BH: Effect of N-acetylcysteineon plasma cysteine and glutathione following paracetamol administration. Eur J Clin Pharmacol, 1989; 36(2): 127-3141.
    • (1989) Eur J Clin Pharmacol , vol.36 , Issue.2 , pp. 127-3141
    • Burgunder, J.M.1    Varriale, A.2    Lauterburg, B.H.3
  • 41
    • 0026472927 scopus 로고
    • Failure of N-acetylcysteineto reduce low-density lipoprotein oxidizability in healthy subjects
    • Kleinveld HA, Demacker PN, Stalenhoef AF: Failure of N-acetylcysteineto reduce low-density lipoprotein oxidizability in healthy subjects. EurJ Clin Pharmacol, 1992; 43(6): 639-4242.
    • (1992) EurJ Clin Pharmacol , vol.43 , Issue.6 , pp. 639-4242
    • Kleinveld, H.A.1    Demacker, P.N.2    Stalenhoef, A.F.3
  • 42
    • 0348047386 scopus 로고    scopus 로고
    • Anaphylactoid reactions to intravenousN-acetylcysteine: A prospective case controlled study
    • Lynch R, Robertson R: Anaphylactoid reactions to intravenousN-acetylcysteine: a prospective case controlled study. Accid EmergNurs, 2004; 12: 10-1543.
    • (2004) Accid EmergNurs , vol.12 , pp. 10-1543
    • Lynch, R.1    Robertson, R.2
  • 43
    • 0034680350 scopus 로고    scopus 로고
    • Cardiac troponin T predicts mortality in patients with end-stage renal disease
    • Dierkes J, Domröse U, Westphal S et al: Cardiac troponin T predicts mortality in patients with end-stage renal disease. Circulation, 2000;102: 1964-6944.
    • (2000) Circulation , vol.102 , pp. 1964-6944
    • Dierkes, J.1    Domröse, U.2    Westphal, S.3
  • 44
    • 0031914677 scopus 로고    scopus 로고
    • Prospective study of hyperhomocysteinemiaas an adverse cardiovascular risk factor in end-stage renal disease
    • Moustapha A, Naso A, Nahlawi M: Prospective study of hyperhomocysteinemiaas an adverse cardiovascular risk factor in end-stage renal disease. Circulation, 1997; 97: 138-4145.
    • (1997) Circulation , vol.97 , pp. 138-4145
    • Moustapha, A.1    Naso, A.2    Nahlawi, M.3
  • 45
    • 0032881782 scopus 로고    scopus 로고
    • N-Acetylcysteine reduces homocysteineplasma levels after single intravenous administration by increasingthiols urinary excretion
    • Ventura P, Panini R, Pasini M et al: N-Acetylcysteine reduces homocysteineplasma levels after single intravenous administration by increasingthiols urinary excretion. Pharmacol Res, 1999; 40: 345-50
    • (1999) Pharmacol Res , vol.40 , pp. 345-350
    • Ventura, P.1    Panini, R.2    Pasini, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.