High negative predictive value of an amplified flow cytometry crossmatch before living donor kidney transplantation

Human Immunology

Volumn 71, Issue 8, 2010, Pages 771-776

  Lindemann, Monika ^a   Nyadu, Bärbel ^a   Heinemann, Falko M ^a   Kribben, Andreas ^a   Paul, Andreas ^a   Horn, Peter A ^a   Witzke, Oliver ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Biotin streptavidin amplifier system; Crossmatch; Flow cytometry; Living donor kidney transplantation; T cell

Indexed keywords

T LYMPHOCYTE ANTIBODY;

ADULT; AGED; ANTIBODY DEPENDENT LYMPHOCYTOTOXICITY; ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLOW CYTOMETRY CROSSMATCH; FLUORESCENCE; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; HUMAN; HUMAN CELL; KIDNEY DONOR; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; PREDICTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REPRODUCIBILITY;

ADOLESCENT; ADULT; AGED; ANTIBODIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRAFT REJECTION; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; T-LYMPHOCYTES; YOUNG ADULT;

EID: 77954760728     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.05.001     Document Type: Article

References (19)

1. Süsal C., Dohler B., Sadeghi M., Ovens J., Opelz G. HLA antibodies and the occurrence of early adverse events in the modern era of transplantation: A collaborative transplant study report. Transplantation 2009, 87:1367-1371.
2. Patel R., Terasaki P.I. Significance of the positive crossmatch test in kidney transplantation. N Engl J Med 1969, 280:735-739.
3. Cho YW, Cecka JM. Crossmatch tests-an analysis of UNOS data from 1991-2000. Clin Transpl 2001:237-46.
4. Scornik J.C., Clapp W., Patton P.R., Van der Werf W.J., Hemming A.W., Reed A.I., Howard R.J. Outcome of kidney transplants in patients known to be flow cytometry crossmatch positive. Transplantation 2001, 71:1098-1102.
5. Karpinski M., Rush D., Jeffery J., Exner M., Regele H., Dancea S., et al. Flow cytometric crossmatching in primary renal transplant recipients with a negative anti-human globulin enhanced cytotoxicity crossmatch. J Am Soc Nephrol 2001, 12:2807-2814.
6. Ishida H., Tanabe K., Furusawa M., Ishizuka T., Hayash T., Tokumoto T., et al. Evaluation of flow cytometric panel reactive antibody in renal transplant recipients - examination of 238 cases of renal transplantation. Transpl Int 2005, 18:163-168.
7. Kerman R.H., Susskind B., Buyse I., Pryzbylowski P., Ruth J., Warnell S., et al. Flow cytometry-detected IgG is not a contraindication to renal transplantation: IgM may be beneficial to outcome. Transplantation 1999, 68:1855-1858.
8. Wen R., Wu V., Dmitrienko S., Yu A., Balshaw R., Keown P.A. Biomarkers in transplantation: Prospective, blinded measurement of predictive value for the flow cytometry crossmatch after negative antiglobulin crossmatch in kidney transplantation. Kidney Int 2006, 70:1474-1481.
9. Gloor J.M., DeGoey S., Ploeger N., Gebel H., Bray R., Moore S.B., et al. Persistence of low levels of alloantibody after desensitization in crossmatch-positive living-donor kidney transplantation. Transplantation 2004, 78:221-227.
10. Matinlauri I.H., Kyllonen L.E., Eklund B.H., Koskimies S.A., Salmela K.T. Weak humoral posttransplant alloresponse after a well-HLA-matched cadaveric kidney transplantation. Transplantation 2004, 78:198-204.
11. Panigrahi A., Deka R., Bhowmik D., Dash S.C., Tiwari S.C., Guleria S., et al. Functional assessment of immune markers of graft rejection: A comprehensive study in live-related donor renal transplantation. Clin Transpl 2006, 20:85-90.
12. Rebibou J.M., Bittencourt M.C., Saint-Hillier Y., Chabod J., Dupont I., Bittard H., et al. T-cell flow-cytometry crossmatch and long-term renal graft survival. Clin Transpl 2004, 18:558-563.
13. Takakura K., Kiuchi T., Kasahara M., Uryuhara K., Uemoto S., Inomata Y., et al. Clinical implications of flow cytometry crossmatch with T or B cells in living donor liver transplantation. Clin Transpl 2001, 15:309-316.
14. Limaye S., O'Kelly P., Harmon G., O'Neill D., Dorman A.M., Walshe J., et al. Improved graft survival in highly sensitized patients undergoing renal transplantation after the introduction of a clinically validated flow cytometry crossmatch. Transplantation 2009, 87:1052-1056.
15. Racusen L.C., Colvin R.B., Solez K., Mihatsch M.J., Halloran P.F., Campbell P.M., et al. Antibody-mediated rejection criteria-an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant 2003, 3:708-714.
16. Zweig M.H., Campbell G. Receiver-operating characteristic (ROC) plots: A fundamental evaluation tool in clinical medicine. Clin Chem 1993, 39:561-577.
17. Murthy K., Stevens L.A., Stark P.C., Levey A.S. Variation in the serum creatinine assay calibration: A practical application to glomerular filtration rate estimation. Kidney Int 2005, 68:1884-1887.
18. Opelz G., Claas F.H. Which human leukocyte antigen antibodies are really clinically relevant?. Hum Immunol 2009, 70:561-562.
19. Zou Y., Heinemann F.M., Grosse-Wilde H., Sireci G., Wang Z., Lavingia B., Stastny P. Detection of anti-mica antibodies in patients awaiting kidney transplantation, during the post-transplant course, and in eluates from rejected kidney allografts by Luminex flow cytometry. Hum Immunol 2006, 67:230-237.