Improved graft survival in highly sensitized patients undergoing renal transplantation after the introduction of a clinically validated flow cytometry crossmatch

Transplantation

Volumn 87, Issue 7, 2009, Pages 1052-1056

  Limaye, Sandhya ^a   O'Kelly, Patrick ^a   Harmon, Grainne ^a   Oĝneill, Derek ^a   Dorman, Anthony M ^a   Walshe, Joseph ^a   Donohoe, John ^a   Little, Dilly ^a   Conlon, Peter J ^a   Keogan, Mary T ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

Crossmatching; Flow cytometry; Renal transplant; Validation

Indexed keywords

ANTIBODY SCREENING; ARTICLE; CLINICAL ARTICLE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLOW CYTOMETRY CROSSMATCH; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY; HUMAN; KIDNEY TRANSPLANTATION; MALE; PREDICTION; PRIORITY JOURNAL; SENSITIZATION; TREATMENT OUTCOME; VALIDATION PROCESS; B LYMPHOCYTE; HISTOCOMPATIBILITY TEST; IMMUNIZATION; IMMUNOLOGY; METHODOLOGY; MORTALITY; PREDICTION AND FORECASTING; SURVIVAL; SURVIVOR; T LYMPHOCYTE;

ALLOANTIBODY;

B-LYMPHOCYTES; FLOW CYTOMETRY; GRAFT SURVIVAL; HISTOCOMPATIBILITY TESTING; HUMANS; IMMUNIZATION; ISOANTIBODIES; KIDNEY TRANSPLANTATION; PREDICTIVE VALUE OF TESTS; SURVIVAL ANALYSIS; SURVIVORS; T-LYMPHOCYTES;

EID: 65549121131     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31819d17b0     Document Type: Article

References (19)

1. Patel R, Terasaki PI. Significance of the positive crossmatch test in kidney transplantation. N Engl J Med 1969; 280: 735.
2. Crespo M, Pascual M, Tolkoff-Rublin N, et al. Acute humoral rejection in renal allograft recipients. I. Incidence, serology and clinical characteristics. Transplantation 2001; 71: 652.
3. Abraham KA, Brown C, Conlon PJ, et al. Plasmapheresis as rescue therapy in accelerated acute humoral rejection. J Clin Apher 2003; 18: 103.
4. Garovoy MR, Rheinschmidt MA, Bigos M, et al. Flow cytometry analysis: A high technology crossmatch technique facilitating transplantation. Transplant Proc 1983; 15: 1939.
5. Chapman JR, Deierhoi MH, Carter NP, et al. Analysis of flow cytometry and cytotoxicity crossmatches in renal transplantation. Transplant Proc 1985; 17: 2480.
6. Leenaerts PL, De Ruysscher D, Vandeputte M, et al. Measurement of alloantibody by flow cytometry. J Immunol Methods 1990; 130: 73.
7. Gebel HM, Bray RA, Nickerson P. Pre-transplant assessment of donorreactive, HLA-specific antibodies in renal transplantation: Contraindication vs. risk. Am J Transplant 2003; 3: 1488.
8. Christiaans MHL, Overhof R, ten Haft A, et al. No advantage of flow cytometry crossmatch over complement-dependent cytotoxicity in immunologically well-documented renal allograft recipients. Transplantation 1996; 62: 1341.
9. Vasilescu ER, Ho EK, Colovai AI, et al. Alloantibodies and the outcome of cadaver kidney allografts. Hum Immunol 2006; 67: 597.
10. Gebel HM, Bray RA. Sensitisation and sensitivity: Defining the unsensitized patient. Transplantation 2000; 69: 1370.
11. Bryan CF, Baier KA, Nelson PW, et al. Long-term graft survival is improved in cadaveric renal retransplantation by flow cytometric crossmatching. Transplantation 1998; 66: 1827.
12. Nelson PW, Eschliman P, Shield CF, et al. Improved graft survival in cadaveric renal retransplantation by flow crossmatching. Arch Surg 1996; 131: 599.
13. Michelon T, Schroeder R, Fagundes I, et al. Clinical relevance of low levels of preformed alloantibodies detected by flow cytometry in the first year post-kidney transplantation. Transplant Proc 2005; 37: 2750.
14. Karpinski M, Rush D, Jeffery J, et al. Flow cytometric crossmatching in primary renal transplant recipients with a negative anti-human globulin enhanced cytotoxicity crossmatch. J AmSoc Nephrol 2001; 12: 2807.
15. Kotb M, Russell WC, Hathaway DK, et al. The use of positive B cell flow cytometry crossmatch in predicting rejection among renal transplant recipients. Clin Transplant 1999; 13(1 Pt 2): 83.
16. Scornik JC, Clapp W, Patoon PR, et al. Outcome of kidney transplants in patients known to be flow cytometry crossmatch positive. Transplantation 2001; 71: 1098.
17. Racusen LC, Colvin RB, Solez K, et al. Antibody-mediated rejection criteria-an addition to the Banff '97 classification of renal allograft rejection. Am J Transplantation 2003; 3: 708.
18. Bray RA, Lebeck LK, Gebel HM. The flow cytometric cross-match: Dual color analysis of T and B cell reactivities. Transplantation 1989; 48: 834.
19. Hopkins KA. The basic lymphocyte microcytotoxicity tests: Standard and AHG enhancement. In: Hahn AB, Land GA, eds. Laboratory Manual. American Society for Histocompatibility and Immunogenetics 2000, pp IC 1.1.