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Chemical Communications

Volumn 46, Issue 29, 2010, Pages 5340-5342

Discovery of potent inhibitor for farnesyl pyrophosphate synthase in the mevalonate pathway

(7) Gao, Jinbo a Chu, Xiusheng a Qiu, Yongge a Wu, Long a Qiao, Yuqin a Wu, Jiasheng a Li, Ding b

a CITY UNIVERSITY OF HONG KONG (Hong Kong)

b SUN YAT SEN UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; FARNESYL PYROPHOSPHATE SYNTHASE; MEVALONIC ACID; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG; ZOLEDRONIC ACID; ENZYME INHIBITOR; TRANSFERASE;

ARTICLE; COLORIMETRY; DEPROTECTION REACTION; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INACTIVATION; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HYDROLYSIS; IC 50; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; IC50; METABOLISM;

ALKYL AND ARYL TRANSFERASES; BIOCATALYSIS; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MEVALONIC ACID; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77954755647 PISSN: 13597345 EISSN: None Source Type: Journal
DOI: 10.1039/c0cc00992j Document Type: Article

Times cited : (18)

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