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Volumn 115, Issue 23, 2010, Pages 4644-4650

C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: Results from genome-wide association and gene expression analyses followed by case-control studies

(21)  Buil, Alfonso a   Trégouët, David Alexandre b   Souto, Juan Carlos a   Saut, Noémie b   Germain, Marine b   Rotival, Maxime b   Tiret, Laurence b   Cambien, Françcois b   Lathrop, Mark c   Zeller, Tanja d   Alessi, Marie Christine b   De Cordoba, Santiago Rodriguez e   Münzel, Thomas d   Wild, Philipp d   Fontcuberta, Jordi a   Gagnon, France f   Emmerich, Joseph b   Almasy, Laura g   Blankenberg, Stefan d   Soria, José Manuel a   more..

b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C4B BINDING PROTEIN; COMPLEMENT COMPONENT C4B BINDING PROTEIN ALPHA6BETA1; COMPLEMENT COMPONENT C4B BINDING PROTEIN ALPHA7BETA; COMPLEMENT COMPONENT C4B BINDING PROTEIN ALPHA7BETA1; MESSENGER RNA; PROTEIN S; UNCLASSIFIED DRUG; C4BPA PROTEIN, HUMAN; C4BPB PROTEIN, HUMAN; HISTOCOMPATIBILITY ANTIGEN;

EID: 77954752114     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-01-263038     Document Type: Article
Times cited : (59)

References (45)
  • 1
    • 33747435832 scopus 로고    scopus 로고
    • Interleukin-6 induction of protein s is regulated through signal transducer and activator of transcription 3
    • de Wolf CJ, Cupers RM, Bertina RM, Vos HL. Interleukin-6 induction of protein s is regulated through signal transducer and activator of transcription 3. Arterioscler Thromb Vasc Biol. 2006;26(9):2168-2174.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.9 , pp. 2168-2174
    • De Wolf, C.J.1    Cupers, R.M.2    Bertina, R.M.3    Vos, H.L.4
  • 2
    • 55249124089 scopus 로고    scopus 로고
    • Regulation of coagulation by protein S
    • Castoldi E, Hackeng TM. Regulation of coagulation by protein S. Curr Opin Hematol. 2008;15(5):529-536.
    • (2008) Curr Opin Hematol , vol.15 , Issue.5 , pp. 529-536
    • Castoldi, E.1    Hackeng, T.M.2
  • 3
    • 0023744090 scopus 로고
    • Inactivation of human factor VIII by activated protein C: Cofactor activity of protein S and protective effect of von Willebrand factor
    • Koedam JA, Meijers JC, Sixma JJ, Bouma BN. Inactivation of human factor VIII by activated protein C: cofactor activity of protein S and protective effect of von Willebrand factor. J Clin Invest. 1988;82(4):1236-1243.
    • (1988) J Clin Invest , vol.82 , Issue.4 , pp. 1236-1243
    • Koedam, J.A.1    Meijers, J.C.2    Sixma, J.J.3    Bouma, B.N.4
  • 4
    • 0028290275 scopus 로고
    • Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa
    • Shen L, Dahlback B. Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa. J Biol Chem. 1994;269(29):18735-18738. (Pubitemid 24226180)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.29 , pp. 18735-18738
    • Shen, L.1    Dahlback, B.2
  • 5
    • 9444273450 scopus 로고    scopus 로고
    • Inhibition of thrombin generation by protein S at low procoagulant stimuli: Implications for maintenance of the hemostatic balance
    • DOI 10.1182/blood-2004-03-1146
    • Seré KM, Rosing J, Hackeng TM. Inhibition of thrombin generation by protein S at low procoagulant stimuli: implications for maintenance of the hemostatic balance. Blood. 2004;104(12):3624-3630. (Pubitemid 39564437)
    • (2004) Blood , vol.104 , Issue.12 , pp. 3624-3630
    • Sere, K.M.1    Rosing, J.2    Hackeng, T.M.3
  • 7
    • 0026654203 scopus 로고
    • Reevaluation of total, free, and bound protein S and C4b-binding protein levels in plasma anticoagulated with citrate or hirudin
    • Griffin JH, Gruber A, Fernandez JA. Reevaluation of total, free, and bound protein S and C4b-binding protein levels in plasma anticoagulated with citrate or hirudin. Blood. 1992;79(12):3203-3211.
    • (1992) Blood , vol.79 , Issue.12 , pp. 3203-3211
    • Griffin, J.H.1    Gruber, A.2    Fernandez, J.A.3
  • 8
    • 0040426308 scopus 로고
    • High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein
    • DOI 10.1073/pnas.78.4.2512
    • Dahlbäck B, Stenflo J. High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein. Proc Natl Acad Sci U S A. 1981;78(4):2512-2516. (Pubitemid 11048838)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.4 II , pp. 2512-2516
    • Dahlback, B.1    Stenflo, J.2
  • 9
    • 0022929854 scopus 로고
    • Inhibition of protein C(a) cofactor function of human and bovine protein S by C4b-binding protein
    • Dahlbäck B. Inhibition of protein Ca cofactor function of human and bovine protein S by C4b-binding protein. J Biol Chem. 1986;261(26):12022-12027. (Pubitemid 17202758)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.26 , pp. 12022-12027
    • Dahlback, B.1
  • 10
    • 34447540033 scopus 로고    scopus 로고
    • The tale of protein S and C4b-binding protein, story of affection
    • DOI 10.1160/TH07-04-0269
    • Dahlbäck B. The tale of protein S and C4b-binding protein, a story of affection. Thromb Haemost. 2007;98(1):90-96. (Pubitemid 47074183)
    • (2007) Thrombosis and Haemostasis , vol.98 , Issue.1 , pp. 90-96
    • Dahlback, B.1
  • 11
    • 42449084553 scopus 로고    scopus 로고
    • Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation
    • Maurissen LF, Thomassen MC, Nicolaes GA, et al. Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation. Blood. 2008;111(6):3034-3041.
    • (2008) Blood , vol.111 , Issue.6 , pp. 3034-3041
    • Maurissen, L.F.1    Thomassen, M.C.2    Nicolaes, G.A.3
  • 12
    • 0034727657 scopus 로고    scopus 로고
    • C4b-binding protein protects coagulation factor Va from inactivation by activated protein C
    • van de Poel RH, Meijers JC, Rosing J, Tans G, Bouma BN. C4b-binding protein protects coagulation factor Va from inactivation by activated protein C. Biochemistry. 2000;39(47):14543-14548.
    • (2000) Biochemistry , vol.39 , Issue.47 , pp. 14543-14548
    • Van De Poel, R.H.1    Meijers, J.C.2    Rosing, J.3    Tans, G.4    Bouma, B.N.5
  • 14
    • 0023227876 scopus 로고
    • Hereditary protein S deficiency: Clinical manifestations
    • Engesser L, BroekmansAW, Briet E, Brommer EJ, Bertina RM. Hereditary protein S deficiency: clinical manifestations. Ann Intern Med. 1987;106(5):677-682. (Pubitemid 17067983)
    • (1987) Annals of Internal Medicine , vol.106 , Issue.5 , pp. 677-682
    • Engesser, L.1    Broekmans, A.W.2    Briet, E.3
  • 15
    • 0021720421 scopus 로고
    • Recurrent venous thromboembolism in patients with a partial deficiency of protein S
    • Comp PC, Esmon CT. Recurrent venous thromboembolism in patients with a partial deficiency of protein S. N Engl J Med. 1984;311(24):1525-1528.
    • (1984) N Engl J Med , vol.311 , Issue.24 , pp. 1525-1528
    • Comp, P.C.1    Esmon, C.T.2
  • 16
    • 1442283872 scopus 로고    scopus 로고
    • Genetic correlation between plasma levels of C4BP isoforms containing beta chains and susceptibility to thrombosis
    • Esparza-Gordillo J, Soria JM, Buil A, et al. Genetic correlation between plasma levels of C4BP isoforms containing beta chains and susceptibility to thrombosis. J Med Genet. 2004;41(1):e5.
    • (2004) J Med Genet , vol.41 , Issue.1
    • Esparza-Gordillo, J.1    Soria, J.M.2    Buil, A.3
  • 17
    • 60849127266 scopus 로고    scopus 로고
    • Clinical relevance of decreased free protein S levels: Results from a retrospective family cohort study involving 1143 relatives
    • Lijfering WM, Mulder R, ten Kate MK, Veeger NJ, Mulder AB, van der Meer J. Clinical relevance of decreased free protein S levels: results from a retrospective family cohort study involving 1143 relatives. Blood. 2009;113(6):1225-1230.
    • (2009) Blood , vol.113 , Issue.6 , pp. 1225-1230
    • Lijfering, W.M.1    Mulder, R.2    Ten Kate, M.K.3    Veeger, N.J.4    Mulder, A.B.5    Van Der Meer, J.6
  • 19
    • 1842557722 scopus 로고    scopus 로고
    • Complement inhibitor C4b-binding protein - Friend or foe in the innate immune system?
    • DOI 10.1016/j.molimm.2003.12.002, PII S0161589003004085
    • Blom AM, Villoutreix BO, Dahlback B. Complement inhibitor C4b-binding protein-friend or foe in the innate immune system? Mol Immunol. 2004;40(18):1333-1346. (Pubitemid 38456985)
    • (2004) Molecular Immunology , vol.40 , Issue.18 , pp. 1333-1346
    • Blom, A.M.1    Villoutreix, B.O.2    Dahlback, B.3
  • 21
    • 0029091398 scopus 로고
    • Isoforms of human C4b-binding protein: I, molecular basis for the C4BP isoform pattern and its variations in human plasma
    • Sánchez-Corral P, Criado Garcia O, Rodriguez de Cordoba S. Isoforms of human C4b-binding protein: I, molecular basis for the C4BP isoform pattern and its variations in human plasma. J Immunol. 1995;155(8):4030-4036.
    • (1995) J Immunol , vol.155 , Issue.8 , pp. 4030-4036
    • Sánchez-Corral, P.1    Criado Garcia, O.2    Rodriguez De Cordoba, S.3
  • 22
    • 0033653710 scopus 로고    scopus 로고
    • Genetic susceptibility to thrombosis and its relationship to physiological risk factors: The GAIT study: genetic analysis of idiopathic thrombophilia
    • Souto JC, Almasy L, Borrell M, et al. Genetic susceptibility to thrombosis and its relationship to physiological risk factors: the GAIT study: genetic analysis of idiopathic thrombophilia. Am J Hum Genet. 2000;67(6):1452-1459.
    • (2000) Am J Hum Genet , vol.67 , Issue.6 , pp. 1452-1459
    • Souto, J.C.1    Almasy, L.2    Borrell, M.3
  • 23
    • 77956637896 scopus 로고    scopus 로고
    • Genetics and beyond - The transcriptome of human monocytes and disease susceptibility
    • Zeller T, Wild P, Szymczak S, et al. Genetics and beyond-the transcriptome of human monocytes and disease susceptibility. PLoS ONE. 2010;5(5):e10693.
    • (2010) PLoS ONE , vol.5 , Issue.5
    • Zeller, T.1    Wild, P.2    Szymczak, S.3
  • 24
    • 67149087360 scopus 로고    scopus 로고
    • Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: Results from a GWAS approach
    • Trégouët DA, Heath S, Saut N, et al. Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach. Blood. 2009;113(21):5298-5303.
    • (2009) Blood , vol.113 , Issue.21 , pp. 5298-5303
    • Trégouët, D.A.1    Heath, S.2    Saut, N.3
  • 26
    • 70349330246 scopus 로고    scopus 로고
    • Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genomewide association study
    • Mälarstig A, Buil A, Souto JC, et al. Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genomewide association study. Blood. 2009;114(7):1417-1422.
    • (2009) Blood , vol.114 , Issue.7 , pp. 1417-1422
    • Mälarstig, A.1    Buil, A.2    Souto, J.C.3
  • 27
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • DOI 10.1086/301844
    • Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet. 1998;62(5):1198-1211. (Pubitemid 28199022)
    • (1998) American Journal of Human Genetics , vol.62 , Issue.5 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 28
    • 34249662218 scopus 로고    scopus 로고
    • A new JAVA interface implementation of THESIAS: Testing haplotype effects in association studies
    • DOI 10.1093/bioinformatics/btm058
    • Tregouet DA, Garelle V. A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies. Bioinformatics. 2007;23(8):1038-1039. (Pubitemid 47050595)
    • (2007) Bioinformatics , vol.23 , Issue.8 , pp. 1038-1039
    • Tregouet, D.A.1    Garelle, V.2
  • 29
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • DOI 10.1093/bioinformatics/bth457
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21(2):263-265. (Pubitemid 40202029)
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 30
    • 0031466983 scopus 로고    scopus 로고
    • From genotypes to genes: Doubling the sample size
    • Sasieni PD. From genotypes to genes: doubling the sample size. Biometrics. 1997;53(4):1253-1261.
    • (1997) Biometrics , vol.53 , Issue.4 , pp. 1253-1261
    • Sasieni, P.D.1
  • 31
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22(4):719-748.
    • (1959) J Natl Cancer Inst , vol.22 , Issue.4 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 32
    • 11244346557 scopus 로고    scopus 로고
    • Variance stabilization applied to microarray data calibration and to the quantification of differential expression
    • Huber W, von Heydebreck A, Sültmann H, Poustka A, Vingron M. Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics. 2002;18(suppl 1):S96-S104
    • (2002) Bioinformatics , vol.18 , Issue.SUPPL. 1
    • Huber, W.1    Von Heydebreck, A.2    Sültmann, H.3    Poustka, A.4    Vingron, M.5
  • 33
    • 77956507050 scopus 로고    scopus 로고
    • Accessed November 12, 2009
    • International HapMap Project. HapMap. http://hapmap.ncbi.nlm.nih.gov. Accessed November 12, 2009.
    • HapMap
  • 34
    • 0037342687 scopus 로고    scopus 로고
    • A quantitative trait locus influencing free plasma protein S levels on human chromosome 1q: Results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) project
    • Almasy L, Soria JM, Souto JC, et al. A quantitative trait locus influencing free plasma protein S levels on human chromosome 1q: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) project. Arterioscler Thromb Vasc Biol. 2003;23(3):508-511.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , Issue.3 , pp. 508-511
    • Almasy, L.1    Soria, J.M.2    Souto, J.C.3
  • 35
    • 0029126988 scopus 로고
    • Isoforms of human C4b-binding protein: II, differential modulation of the C4BPA and C4BPB genes by acute phase cytokines
    • Criado García O, Sanchez-Corral P, Rodriguez de Cordoba S. Isoforms of human C4b-binding protein: II, differential modulation of the C4BPA and C4BPB genes by acute phase cytokines. J Immunol. 1995;155(8):4037-4043.
    • (1995) J Immunol , vol.155 , Issue.8 , pp. 4037-4043
    • Criado García, O.1    Sanchez-Corral, P.2    Rodriguez De Cordoba, S.3
  • 36
    • 0028103281 scopus 로고
    • Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S
    • García de Frutos P, Alim RI, Hardig Y, Zoller B, Dahlback B. Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S. Blood. 1994;84(3):815-822.
    • (1994) Blood , vol.84 , Issue.3 , pp. 815-822
    • García De Frutos, P.1    Alim, R.I.2    Hardig, Y.3    Zoller, B.4    Dahlback, B.5
  • 37
    • 0141609935 scopus 로고    scopus 로고
    • Inflammation and thrombosis
    • Esmon CT. Inflammation and thrombosis. J Thromb Haemost. 2003;1(7):1343-1348.
    • (2003) J Thromb Haemost , vol.1 , Issue.7 , pp. 1343-1348
    • Esmon, C.T.1
  • 39
    • 49449116055 scopus 로고    scopus 로고
    • Inflammation, C-reactive protein, and atherothrombosis
    • Ridker PM, Silvertown JD. Inflammation, C-reactive protein, and atherothrombosis. J Periodontol. 2008;79(8):1544-1551.
    • (2008) J Periodontol , vol.79 , Issue.8 , pp. 1544-1551
    • Ridker, P.M.1    Silvertown, J.D.2
  • 40
    • 69249231007 scopus 로고    scopus 로고
    • Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study
    • Reiner AP, Lange LA, Smith NL, Zakai NA, Cushman M, Folsom AR. Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study. J Thromb Haemost. 2009;7(9):1499-1505.
    • (2009) J Thromb Haemost , vol.7 , Issue.9 , pp. 1499-1505
    • Reiner, A.P.1    Lange, L.A.2    Smith, N.L.3    Zakai, N.A.4    Cushman, M.5    Folsom, A.R.6
  • 42
    • 63149095644 scopus 로고    scopus 로고
    • Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix
    • Happonen KE, Sjoberg AP, Morgelin M, Heinegard D, Blom AM. Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix. J Immunol. 2009;182(3):1518-1525.
    • (2009) J Immunol , vol.182 , Issue.3 , pp. 1518-1525
    • Happonen, K.E.1    Sjoberg, A.P.2    Morgelin, M.3    Heinegard, D.4    Blom, A.M.5
  • 44
    • 51449108790 scopus 로고    scopus 로고
    • C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3
    • doi:10.1371/journal.pone.0002886
    • Trouw LA, Okroj M, Kupreishvili K, et al. C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3. PLoS ONE. 2008;3(8):e2886. doi:10.1371/journal.pone.0002886.
    • (2008) PLoS ONE , vol.3 , Issue.8
    • Trouw, L.A.1    Okroj, M.2    Kupreishvili, K.3
  • 45
    • 75349095022 scopus 로고    scopus 로고
    • Deciphering the molecular basis to venous thromboembolism: Where are we and where should we go?
    • Morange PE, Tregouet DA. Deciphering the molecular basis to venous thromboembolism: where are we and where should we go? Br J Haematol. 2010;148(4):495-506.
    • (2010) Br J Haematol , vol.148 , Issue.4 , pp. 495-506
    • Morange, P.E.1    Tregouet, D.A.2


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