메뉴 건너뛰기




Volumn 49, Issue 8, 2010, Pages 1466-1471

Vitamin D3 down-regulates intracellular Toll-like receptor 9 expression and Toll-like receptor 9-induced IL-6 production in human monocytes

Author keywords

IL 6; Systemic lupus erythematosus; TLR9; Toll like receptors; Vitamin D3

Indexed keywords

CD14 ANTIGEN; COLECALCIFEROL; INTERLEUKIN 6; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR 9 AGONIST; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 77954703735     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keq124     Document Type: Article
Times cited : (145)

References (25)
  • 1
    • 33847183077 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor signals in innate immune defence
    • Trinchieri G, Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev 2007;7:79-90.
    • (2007) Nat Rev , vol.7 , pp. 79-90
    • Trinchieri, G.1    Sher, A.2
  • 2
    • 34249677845 scopus 로고    scopus 로고
    • Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
    • Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 2007;13:52-9.
    • (2007) Nat Med , vol.13 , pp. 52-59
    • Kanzler, H.1    Barrat, F.J.2    Hessel, E.M.3    Coffman, R.L.4
  • 3
    • 33750953650 scopus 로고    scopus 로고
    • Expansion of Toll-like receptor 9-expressing B cells in active sys-temic lupus erythematosus: implications for the induction and maintenance of the autoimmune process
    • Papadimitraki ED, Choulaki C, Koutala E et al. Expansion of Toll-like receptor 9-expressing B cells in active sys-temic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum 2006;54:3601-11.
    • (2006) Arthritis Rheum , vol.54 , pp. 3601-3611
    • Papadimitraki, E.D.1    Choulaki, C.2    Koutala, E.3
  • 4
    • 33745864016 scopus 로고    scopus 로고
    • Role of TLR9 in anti-nucleosome and anti-DNA antibody production in LPR mutation-induced murine lupus
    • Lartigue A, Courville P, Auquit I et al. Role of TLR9 in anti-nucleosome and anti-DNA antibody production in LPR mutation-induced murine lupus. J Immunol 2006;177:49-54.
    • (2006) J Immunol , vol.177 , pp. 49-54
    • Lartigue, A.1    Courville, P.2    Auquit, I.3
  • 5
    • 4043115543 scopus 로고    scopus 로고
    • Topical paricalcitol (19-nor-1 alpha,25-dihydroxyvitamin D2) is a novel, safe and effective treatment for plaque psoriasis: a pilot study
    • Durakovic C, Ray S, Holick MF. Topical paricalcitol (19-nor-1 alpha,25-dihydroxyvitamin D2) is a novel, safe and effective treatment for plaque psoriasis: a pilot study. Br J Dermatol 2004;151:90-5.
    • (2004) Br J Dermatol , vol.151 , pp. 90-95
    • Durakovic, C.1    Ray, S.2    Holick, M.F.3
  • 6
    • 68549092572 scopus 로고    scopus 로고
    • Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer
    • Flanagan JN, Zheng S, Chiang KC et al. Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer. Anticancer Res 2009;29:47-53.
    • (2009) Anticancer Res , vol.29 , pp. 47-53
    • Flanagan, J.N.1    Zheng, S.2    Chiang, K.C.3
  • 7
    • 50249179101 scopus 로고    scopus 로고
    • Vitamin effects on the immune system: vitamins A and D take centre stage
    • Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev 2008;8:685-98.
    • (2008) Nat Rev , vol.8 , pp. 685-698
    • Mora, J.R.1    Iwata, M.2    von Andrian, U.H.3
  • 8
    • 77951253745 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3
    • Jeffery LE, Burke F, Mura M et al. 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. J Immunol 2009;183:58-67.
    • (2009) J Immunol , vol.183 , pp. 58-67
    • Jeffery, L.E.1    Burke, F.2    Mura, M.3
  • 9
    • 32944464959 scopus 로고    scopus 로고
    • Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns
    • Sadeghi K, Wessner B, Laggner U et al. Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns. Eur J Immunol 2006;36:61-70.
    • (2006) Eur J Immunol , vol.36 , pp. 61-70
    • Sadeghi, K.1    Wessner, B.2    Laggner, U.3
  • 10
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G, Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 2000;164:2405-11.
    • (2000) J Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 11
    • 0027332649 scopus 로고
    • 1,25-Dihydroxyvitamin D3 exerts opposing effects to IL-4 on MHC class-II antigen expression, accessory activity and phagocytosis of human monocytes
    • Xu H, Soruri A, Gieseler RK, Peters JH. 1,25-Dihydroxyvitamin D3 exerts opposing effects to IL-4 on MHC class-II antigen expression, accessory activity and phagocytosis of human monocytes. Scand J Immunol 1993;38:35-40.
    • (1993) Scand J Immunol , vol.38 , pp. 35-40
    • Xu, H.1    Soruri, A.2    Gieseler, R.K.3    Peters, J.H.4
  • 12
    • 69949184887 scopus 로고    scopus 로고
    • Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin
    • Yuk JM, Shin DM, Lee HM et al. Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin. Cell Host Microbe 2009;6:31-43.
    • (2009) Cell Host Microbe , vol.6 , pp. 31-43
    • Yuk, J.M.1    Shin, D.M.2    Lee, H.M.3
  • 13
    • 0346458588 scopus 로고    scopus 로고
    • Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study
    • Merlino LA, Curtis J, Mikuls TR, Cerhan JR, Criswell LA, Saag KG. Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study. Arthritis Rheum 2004;50:72-7.
    • (2004) Arthritis Rheum , vol.50 , pp. 72-77
    • Merlino, L.A.1    Curtis, J.2    Mikuls, T.R.3    Cerhan, J.R.4    Criswell, L.A.5    Saag, K.G.6
  • 15
    • 0026772395 scopus 로고
    • 1,25-Dihydroxyvitamin D3 attenuates the expression of experimental murine lupus of MRL/l mice
    • Lemire JM, Ince A, Takashima M. 1,25-Dihydroxyvitamin D3 attenuates the expression of experimental murine lupus of MRL/l mice. Autoimmunity 1992;12:43-8.
    • (1992) Autoimmunity , vol.12 , pp. 43-48
    • Lemire, J.M.1    Ince, A.2    Takashima, M.3
  • 17
    • 0035802695 scopus 로고    scopus 로고
    • Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study
    • Hypponen E, Laara E, Reunanen A, Jarvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 2001;358:1500-3.
    • (2001) Lancet , vol.358 , pp. 1500-1503
    • Hypponen, E.1    Laara, E.2    Reunanen, A.3    Jarvelin, M.R.4    Virtanen, S.M.5
  • 19
    • 47249148081 scopus 로고    scopus 로고
    • Low levels of 25-hydroxyvitamin D (25OHD) in patients with inflammatory bowel disease and its correlation with bone mineral density
    • Souza HN, Lora FL, Kulak CA, Manas NC, Amarante HM, Borba VZ. Low levels of 25-hydroxyvitamin D (25OHD) in patients with inflammatory bowel disease and its correlation with bone mineral density. Arq Bras Endocrinol Metabol 2008;52:84-91.
    • (2008) Arq Bras Endocrinol Metabol , vol.52 , pp. 84-91
    • Souza, H.N.1    Lora, F.L.2    Kulak, C.A.3    Manas, N.C.4    Amarante, H.M.5    Borba, V.Z.6
  • 20
    • 44149111801 scopus 로고    scopus 로고
    • 3 in human monocytes systematic review and meta-analysis
    • 3 in human monocytes systematic review and meta-analysis. Arch Dis Child 2008;93:512-7.
    • (2008) Arch Dis Child , vol.93 , pp. 512-517
    • Zipitis, C.S.1    Akobeng, A.K.2
  • 21
    • 0031908097 scopus 로고    scopus 로고
    • 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis
    • Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr 1998;128:68-72.
    • (1998) J Nutr , vol.128 , pp. 68-72
    • Cantorna, M.T.1    Hayes, C.E.2    DeLuca, H.F.3
  • 22
    • 60649092297 scopus 로고    scopus 로고
    • Regulation by 1, 25-dihydroxy-vitamin D3 on altered TLRs expression and response to ligands of monocyte from autoimmune diabetes
    • Du T, Zhou ZG, You S et al. Regulation by 1, 25-dihydroxy-vitamin D3 on altered TLRs expression and response to ligands of monocyte from autoimmune diabetes. Clin Chim Acta 2009;402:33-8.
    • (2009) Clin Chim Acta , vol.402 , pp. 33-38
    • Du, T.1    Zhou, Z.G.2    You, S.3
  • 23
    • 34247158555 scopus 로고    scopus 로고
    • Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory
    • Giulietti A, van Etten E, Overbergh L, Stoffels K, Bouillon R, Mathieu C. Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract 2007;77:47-57.
    • (2007) Diabetes Res Clin Pract , vol.77 , pp. 47-57
    • Giulietti, A.1    van Etten, E.2    Overbergh, L.3    Stoffels, K.4    Bouillon, R.5    Mathieu, C.6
  • 24
    • 69149106547 scopus 로고    scopus 로고
    • Monocytes and T lymphocytes contribute to a predominance of interleukin 6 and interleukin 10 in systemic lupus erythematosus
    • Mellor-Pita S, Citores MJ, Castejon R et al. Monocytes and T lymphocytes contribute to a predominance of interleukin 6 and interleukin 10 in systemic lupus erythematosus. Cytometry B Clin Cytom 2009;76B:61-70.
    • (2009) Cytometry B Clin Cytom , vol.76 B , pp. 61-70
    • Mellor-Pita, S.1    Citores, M.J.2    Castejon, R.3
  • 25
    • 33750011260 scopus 로고    scopus 로고
    • Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus
    • Liang B, Gardner DB, Griswold DE, Bugelski PJ, Song XY. Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus. Immunology 2006;119:296-305.
    • (2006) Immunology , vol.119 , pp. 296-305
    • Liang, B.1    Gardner, D.B.2    Griswold, D.E.3    Bugelski, P.J.4    Song, X.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.