New protocol to obtain spirolides from Alexandrium ostenfeldii cultures with high recovery and purity

Biomedical Chromatography

Volumn 24, Issue 8, 2010, Pages 878-886

  Otero, Paz ^a   Alfonso, Amparo ^a   Alfonso, Carmen ^a   Vieytes, Mercedes R ^a   Louzao, M Carmen ^a   Botana, Ana M ^a   Botana, Luis M ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

13,19 didesmethyl spirolide C; Analytical and preparative methodology; LC MS; Purification, 13 desmethyl spirolide C; Spirolides

Indexed keywords

EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHASE SEPARATION; SHELLFISH; TOXIC MATERIALS;

13,19-DIDESMETHYL SPIROLIDE C; 13-DESMETHYL SPIROLIDE C; ALEXANDRIUM OSTENFELDII; ANALYTICAL AND PREPARATIVE METHODOLOGY; LARGE AMOUNTS; LC-MS; PARALYTIC SHELLFISH POISONING; PURIFICATION, 13-DESMETHYL SPIROLIDE C; SHELLFISH POISONING TOXINS; SPIROLIDES;

PURIFICATION;

13 NORSPIROLIDE C; 13,19 DINORSPIROLIDE C; NEUROTOXIN; SPIROLIDE; UNCLASSIFIED DRUG; MARINE TOXIN; SPIRO COMPOUND;

ALEXANDRIUM OSTENFELDII; ARTICLE; CHEMICAL STRUCTURE; CULTURE TECHNIQUE; DENMARK; DINOFLAGELLATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MARINE ENVIRONMENT; MASS SPECTROMETER; MASS SPECTROMETRY; NEUROTOXICITY; NONHUMAN; PHYTOPLANKTON; PURIFICATION; SALINITY; SHELLFISH POISONING; SOLID PHASE EXTRACTION; TEMPERATURE; TOXIN ANALYSIS; CHEMISTRY; EVALUATION STUDY; ISOLATION AND PURIFICATION; PROCEDURES;

ALEXANDRIUM OSTENFELDII; DINOPHYCEAE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINOFLAGELLIDA; MARINE TOXINS; MASS SPECTROMETRY; PHYTOPLANKTON; SPIRO COMPOUNDS;

EID: 77954696728     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1380     Document Type: Article

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