Magnesium hydroxide temporarily enhancing osteoblast activity and decreasing the osteoclast number in peri-implant bone remodelling

Acta Biomaterialia

Volumn 6, Issue 5, 2010, Pages 1861-1868

  Janning, C ^a   Willbold, E ^a   Vogt, C ^b   Nellesen, J ^c   Meyer Lindenberg, A ^d   Windhagen, H ^a   Thorey, F ^a   Witte, F ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Institut für Anorganische Chemie   (Germany)

^c TU DORTMUND UNIVERSITY   (Germany)

^d UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Animal model; Bone remodelling; Corrosion product; Magnesium; Microtomography

Indexed keywords

ALLOYING ELEMENTS; BONE; CORROSION; CYLINDERS (SHAPES); MAGNESIUM ALLOYS; METAL IONS;

ANIMAL MODEL; BONE GROWTH; BONE REMODELLING; CORROSION PRODUCTS; ELECTROCHEMICAL INTERACTIONS; IN-VIVO; INTERACTION EFFECT; METAL SURFACES; MICRO-TOMOGRAPHY; PERI-IMPLANT BONES;

MAGNESIUM COMPOUNDS;

ALLOY; MAGNESIUM; MAGNESIUM HYDROXIDE; BIOMATERIAL; MINERAL;

ANIMAL EXPERIMENT; ARTICLE; BONE GROWTH; BONE MASS; BONE REMODELING; CELL ACTIVITY; CELL COUNT; CELL SURFACE; CONTROLLED STUDY; CORROSION; DISSOLUTION; FEMALE; FEMUR CONDYLE; IMPLANT; IN VIVO STUDY; MALE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOID; OSTEOLYSIS; PRIORITY JOURNAL; RABBIT; ANIMAL; BONE; BONE DEVELOPMENT; CYTOLOGY; DRUG EFFECT; FLUORESCENCE; IMPLANTATION; MATERIALS TESTING; METABOLISM; PATHOLOGY; STAINING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE AND BONES; BONE REMODELING; CELL COUNT; FEMALE; FLUORESCENCE; IMPLANTS, EXPERIMENTAL; MAGNESIUM HYDROXIDE; MATERIALS TESTING; MINERALS; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; PROSTHESIS IMPLANTATION; RABBITS; STAINING AND LABELING;

EID: 77954661736     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.12.037     Document Type: Article

References (37)

1. F. Witte, V. Kaese, H. Haferkamp, E. Switzer, A. Meyer-Lindenberg, and C.J. Wirth In vivo corrosion of four magnesium alloys and the associated bone response Biomaterials 26 2005 3557 3563
2. F. Witte Cartilage repair on magnesium scaffolds used as a subchondral bone replacement Materialwissensch Werkstofftech 37 2006 504 508
3. F. Witte, H. Ulrich, M. Rudert, and E. Willbold Biodegradable magnesium scaffolds: Part 1: appropriate inflammatory response J Biomed Mater Res A 81 2007 748 756
4. A. Lambotte Technique et indications de la prothse perdue dans la traitement des fractures Presse Med Belge 17 1909 321 323
5. J. Verbrugge L'utilisation du magnésium dans le traitement chirurgical des fractures Bull Mém Soc Nat Cir 59 1937 813 823
6. F. Witte, H. Ulrich, C. Palm, and E. Willbold Biodegradable magnesium scaffolds. Part II: Peri-implant bone remodeling J Biomed Mater Res A 81 2007 757 765
7. L.P. Xu, G.N. Yu, E. Zhang, F. Pan, and K. Yang In vivo corrosion behavior of Mg-Mn-Zn alloy for bone implant application J Biomed Mater Res A 83 2007 703 711
8. J.A. Spadaro Electrically enhanced osteogenesis at various metal cathodes J Biomed Mater Res 16 1982 861 873
9. P.R. Supronowicz, P.M. Ajayan, K.R. Ullmann, B.P. Arulanandam, D.W. Metzger, and R. Bizios Novel current-conducting composite substrates for exposing osteoblasts to alternating current stimulation J Biomed Mater Res 59 2002 499 506
10. I.S. Kim Biphasic electric current stimulates proliferation and induces VEGF production in osteoblasts Biochim Biophys Acta 1763 2006 907 916
11. C.A. Bassett, R.J. Pawluk, and R.O. Becker Effects of electric currents on bone in vivo Nature 204 1964 652 654
12. M. Noda, and A. Sato Appearance of osteoclasts and osteoblasts in electrically stimulated bones cultured on chorioallantoic membranes Clin Orthop Relat Res 193 1985 288 298
13. F. Witte, N. Hort, C. Vogt, S. Cohen, K.U. Kainer, and R. Willumeit Degradable biomaterials based on magnesium corrosion Curr Opin Solid State Mater Sci 12 2008 63 72
14. A. Wennerberg, T. Albrektsson, C. Johansson, and B. Andersson Experimental study of turned and grit-blasted screw-shaped implants with special emphasis on effects of blasting material and surface topography Biomaterials 17 1996 15 22
15. K. Kieswetter, Z. Schwartz, D.D. Dean, and B.D. Boyan The role of implant surface characteristics in the healing of bone Crit Rev Oral Biol Med 7 1996 329 345
16. Z. Schwartz, and B.D. Boyan Underlying mechanisms at the bone-biomaterial interface J Cell Biochem 56 1994 340 347
17. A.V. Rousselle, D. Heymann, V. Demais, C. Charrier, N. Passuti, and M.F. Basle Influence of metal ion solutions on rabbit osteoclast activities in vitro Histol Histopathol 17 2002 1025 1032
18. F. Luthen, U. Bulnheim, P.D. Mueller, J. Rychly, H. Jesswein, and J.G.B. Nebe Influence of manganese ions on cellular behavior of human osteoblasts in vitro Biomol Eng 24 2007 531 536
19. D.A. Bushinsky Metabolic alkalosis decreases bone calcium efflux by suppressing osteoclasts and stimulating osteoblasts Am J Physiol 271 1 Pt 2 1996 F216 F222
20. C.C. Liu, J.K. Yeh, and J.F. Aloia Magnesium directly stimulates osteoblast proliferation J Bone Miner Res 3 1988 S104
21. F. Feyerabend, F. Witte, M. Kammal, and R. Willumeit Unphysiologically high magnesium concentrations support chondrocyte proliferation and redifferentiation Tissue Eng 12 2006 3545 3556
22. G.L. Makar, and J. Kruger Corrosion of magnesium Int Mater Rev 38 1993 138 153
23. G.L. Song, and A. Atrens Corrosion mechanisms of magnesium alloys Adv Eng Mater 1 1999 11 33
24. B.A. Shaw ASM corrosion handbook Anti-Corros Methods Mater 50 4 2003 13A
25. R.B. Cady, J.A. Siegel, G. Mathien, J.A. Spadaro, and S.E. Chase Physeal response to absorbable polydioxanone bone pins in growing rabbits J Biomed Mater Res 48 1999 211 215
26. V.F. Stenport, C. Johansson, S.J. Heo, P. Aspenberg, and T. Albrektsson Titanium implants and BMP-7 in bone: an experimental model in the rabbit J Mater Sci Mater Med 14 2003 247 254
27. O.M. Böstman, O.M. Laitinen, O. Tynninen, S.T. Salminen, and H.K. Pihlajamäki Tissue restoration after resorption of polyglycolide and poly-laevo-lactic acid screws J Bone Joint Surg Br 87 2005 1575 1580
28. M. Hoshino, T. Egi, H. Terai, T. Namikawa, and K. Takaoka Regenerative repair of long intercalated rib defects using porous cylinders of beta-tricalcium phosphate: an experimental study in a canine model Plast Reconstr Surg 119 2007 1431 1439
29. P. Hahn-Weinheimer, A. Hirner, and K. Weber-Diefenbach Röntgenfluoreszenzanalytische Methoden 2nd ed. 2000 Springer Berlin
30. A.M. Parfitt Bone histomorphometry: standardization of nomenclature, symbols and units (summary of proposed system) Bone 9 1988 67 69
31. S. Vedi, and J. Compston Bone histomorphometry M.H. Helfrich, S.H. Ralston, Bone research protocols 2003 Humana Press Totowa, NJ 283 298
32. A.G. Robling, A.B. Castillo, and C.H. Turner Biomechanical and molecular regulation of bone remodeling Annu Rev Biomed Eng 8 2006 455 498
33. A.M. Parfitt The mechanism of coupling: a role for the vasculature Bone 26 2000 319 323
34. R.K. Rude, H.E. Gruber, H.J. Norton, L.Y. Wei, A. Frausto, and J. Kilburn Reduction of dietary magnesium by only 50% in the rat disrupts bone and mineral metabolism Osteoporos Int 17 2006 1022 1032
35. R.K. Rude, M.E. Kirchen, H.E. Gruber, M.H. Meyer, J.S. Luck, and D.L. Crawford Magnesium deficiency-induced osteoporosis in the rat: uncoupling of bone formation and bone resorption Magn Res 12 1999 257 267
36. R.K. Rude, H.E. Gruber, L.Y. Wei, A. Frausto, and B.G. Mills Magnesium deficiency: effect on bone and mineral metabolism in the mouse Calcif Tissue Int 72 2003 32 41 (Pubitemid 36918935)
37. R.K. Rude, H.E. Gruber, H.J. Norton, L.Y. Wei, A. Frausto, and B.G. Mills Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor-alpha J Nutr 134 2004 79 85