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Volumn 51, Issue 6, 2010, Pages 984-993

Adverse effects of valproate on bone: Defining a model to investigate the pathophysiology

Author keywords

Antiepileptic drugs; Bone; Dual energy x ray absorptiometry; Mice; Valproate

Indexed keywords

VALPROIC ACID;

EID: 77954651350     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2009.02516.x     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 70449660048 scopus 로고    scopus 로고
    • Valproate
    • Perucca E, Shorvon S, Fish DR, Dodson E (eds) Blackwell, Oxford
    • Arroyo S. (2004) Valproate. In Perucca E, Shorvon S, Fish DR, Dodson E (eds) The treatment of epilepsy. Blackwell, Oxford.
    • (2004) The Treatment of Epilepsy
    • Arroyo, S.1
  • 2
    • 1842786823 scopus 로고    scopus 로고
    • The effect of valproate on bone mineral density in adult epileptic patients
    • DOI 10.1016/j.phrs.2003.11.011, PII S1043661803003797
    • Boluk A, Guzelipek M, Savli H, Temel I, Ozisik HI, Kaygusuz A. (2004) The effect of valproate on bone mineral density in adult epileptic patients. Pharmacol Res 50:93-97. (Pubitemid 38479673)
    • (2004) Pharmacological Research , vol.50 , Issue.1 , pp. 93-97
    • Boluk, A.1    Guzelipek, M.2    Savli, H.3    Temel, I.4    Ozisik, H.I.5    Kaygusuz, A.6
  • 3
    • 0037008255 scopus 로고    scopus 로고
    • Interaction of the neurosteroid alphaxalone with conventional antiepileptic drugs in different types of experimental seizures
    • Borowicz KK, Zadrozniak M, Swiader M, Kowalska A, Kleinrok Z, Czuczwar SJ. (2002) Interaction of the neurosteroid alphaxalone with conventional antiepileptic drugs in different types of experimental seizures. Eur J Pharmacol 449(1-2):85-90.
    • (2002) Eur J Pharmacol , vol.449 , Issue.1-2 , pp. 85-90
    • Borowicz, K.K.1    Zadrozniak, M.2    Swiader, M.3    Kowalska, A.4    Kleinrok, Z.5    Czuczwar, S.J.6
  • 4
    • 27144453009 scopus 로고    scopus 로고
    • Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors
    • DOI 10.1002/jcb.20544
    • Cho HH, Park HT, Kim YJ, Bae YC, Suh KT, Jung JS. (2005) Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors. J Cell Biochem 96:533-542. (Pubitemid 41504651)
    • (2005) Journal of Cellular Biochemistry , vol.96 , Issue.3 , pp. 533-542
    • Cho, H.H.1    Park, H.T.2    Kim, Y.J.3    Bae, Y.C.4    Suh, K.T.5    Jung, J.S.6
  • 6
    • 2942562767 scopus 로고    scopus 로고
    • Antiepileptic drug use increases rates of bone loss in older women: A prospective study
    • Ensrud KE, Walczak TS, Blackwell T, Ensrud ER, Bowman PJ, Stone KL. (2004) Antiepileptic drug use increases rates of bone loss in older women: a prospective study. Neurology 62:2051-2057. (Pubitemid 38738220)
    • (2004) Neurology , vol.62 , Issue.11 , pp. 2051-2057
    • Ensrud, K.E.1    Walczak, T.S.2    Blackwell, T.3    Ensrud, E.R.4    Bowman, P.J.5    Stone, K.L.6
  • 8
    • 0034097478 scopus 로고    scopus 로고
    • Long-term anticonvulsant therapy leads to low bone mineral density-evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells
    • Feldkamp J, Becker A, Witte OW, Scharff D, Scherbaum WA. (2000) Long-term anticonvulsant therapy leads to low bone mineral density-evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells. Exp Clin Endocrinol Diabetes 108:37-43.
    • (2000) Exp Clin Endocrinol Diabetes , vol.108 , pp. 37-43
    • Feldkamp, J.1    Becker, A.2    Witte, O.W.3    Scharff, D.4    Scherbaum, W.A.5
  • 9
    • 33845950340 scopus 로고    scopus 로고
    • Antiepileptic drugs and their impact on balance
    • Fife T, Sirven J. (2005) Antiepileptic drugs and their impact on balance. Aging Health 1:147-155.
    • (2005) Aging Health , vol.1 , pp. 147-155
    • Fife, T.1    Sirven, J.2
  • 10
    • 29444460645 scopus 로고    scopus 로고
    • Progress in pharmaceutical development presentation with improved pharmacokinetics: A new formulation for valproate
    • Genton P. (2005) Progress in pharmaceutical development presentation with improved pharmacokinetics: a new formulation for valproate. Acta Neurol Scand Suppl 182:26-32.
    • (2005) Acta Neurol Scand Suppl , vol.182 , pp. 26-32
    • Genton, P.1
  • 11
    • 0034794545 scopus 로고    scopus 로고
    • Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy
    • Guo CY, Ronen GM, Atkinson SA. (2001) Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy. Epilepsia 42:1141-1147.
    • (2001) Epilepsia , vol.42 , pp. 1141-1147
    • Guo, C.Y.1    Ronen, G.M.2    Atkinson, S.A.3
  • 12
    • 0042868293 scopus 로고    scopus 로고
    • Valproate: Past, present, and future
    • Johannessen CU, Johannessen SI. (2003) Valproate: past, present, and future. CNS Drug Rev 9(2):199-216.
    • (2003) CNS Drug Rev , vol.9 , Issue.2 , pp. 199-216
    • Johannessen, C.U.1    Johannessen, S.I.2
  • 13
    • 0033045923 scopus 로고    scopus 로고
    • Effect of antiepileptic drugs on bone mineral density in children between ages 6 and 12 years
    • Kafali G, Erselcan T, Tanzer F. (1999) Effect of antiepileptic drugs on bone mineral density in children between ages 6 and 12 years. Clin Pediatr (Phila) 38:93-98. (Pubitemid 29086791)
    • (1999) Clinical Pediatrics , vol.38 , Issue.2 , pp. 93-98
    • Kafali, G.1    Erselcan, T.2    Tanzer, F.3
  • 14
    • 0014292570 scopus 로고
    • Osteopathies in antiepileptic long-term therapy (preliminary report)
    • Kruse R. (1968) [Osteopathies in antiepileptic long-term therapy (preliminary report)]. Monatsschr Kinderheilkd 116:378-381.
    • (1968) Monatsschr Kinderheilkd , vol.116 , pp. 378-381
    • Kruse, R.1
  • 16
    • 0037742375 scopus 로고    scopus 로고
    • Valproate: A reappraisal of its pharmacodynamic properties and mechanisms of action
    • Loscher W. (1999) Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action. Prog Neurobiol 58:31-59.
    • (1999) Prog Neurobiol , vol.58 , pp. 31-59
    • Loscher, W.1
  • 20
  • 21
    • 27444443677 scopus 로고    scopus 로고
    • Genetic variation in bone growth patterns defines adult mouse bone fragility
    • Price C, Herman BC, Lufkin T, Goldman HM, Jepsen KJ. (2005) Genetic variation in bone growth patterns defines adult mouse bone fragility. J Bone Miner Res 20:1983-1991.
    • (2005) J Bone Miner Res , vol.20 , pp. 1983-1991
    • Price, C.1    Herman, B.C.2    Lufkin, T.3    Goldman, H.M.4    Jepsen, K.J.5
  • 22
    • 0343445201 scopus 로고    scopus 로고
    • The effects of valproate, carbamazepine, and oxcarbazepine on growth and sexual maturation in girls with epilepsy
    • DOI 10.1542/peds.103.3.588
    • Rattya J, Vainionpaa L, Knip M, Lanning P, Isojarvi JI. (1999) The effects of valproate, carbamazepine, and oxcarbazepine on growth and sexual maturation in girls with epilepsy. Pediatrics 103(3):588-593. (Pubitemid 29274505)
    • (1999) Pediatrics , vol.103 , Issue.3 , pp. 588-593
    • Rattya, J.1    Vainionpa, L.2    Knip, M.3    Lanning, P.4    Isojarvi, J.I.T.5
  • 23
    • 0035653766 scopus 로고    scopus 로고
    • Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine
    • Rieger-Wettengl G, Tutlewski B, Stabrey A, Rauch F, Herkenrath P, Schauseil-Zipf U, Schoenau E. (2001) Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine. Pediatrics 108:E107.
    • (2001) Pediatrics , vol.108
    • Rieger-Wettengl, G.1    Tutlewski, B.2    Stabrey, A.3    Rauch, F.4    Herkenrath, P.5    Schauseil-Zipf, U.6    Schoenau, E.7
  • 24
    • 0020453558 scopus 로고
    • Reduced bone growth in rats treated with anticonvulsant drugs: A type II pseudohypoparathyroidism?
    • Robinson PB, Harris M, Harvey W, Papadogeorgakis N. (1982) Reduced bone growth in rats treated with anticonvulsant drugs: a type II pseudohypoparathyroidism? Metab Bone Dis Relat Res 4(4):269-275.
    • (1982) Metab Bone Dis Relat Res , vol.4 , Issue.4 , pp. 269-275
    • Robinson, P.B.1    Harris, M.2    Harvey, W.3    Papadogeorgakis, N.4
  • 25
    • 0035859862 scopus 로고    scopus 로고
    • Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy
    • Sato Y, Kondo I, Ishida S, Motooka H, Takayama K, Tomita Y, Maeda H, Satoh K. (2001) Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy. Neurology 57:445-449. (Pubitemid 32757591)
    • (2001) Neurology , vol.57 , Issue.3 , pp. 445-449
    • Sato, Y.1    Kondo, I.2    Ishida, S.3    Motooka, H.4    Takayama, K.5    Tomita, Y.6    Maeda, H.7    Satoh, K.8
  • 26
    • 1842716689 scopus 로고    scopus 로고
    • Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton compared with histology and microcomputed tomography (microCT)
    • Schmidt C, Priemel M, Kohler T, Weusten A, Muller R, Amling M, Eckstein F. (2003) Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton compared with histology and microcomputed tomography (microCT). J Bone Miner Res 18:1486-1496.
    • (2003) J Bone Miner Res , vol.18 , pp. 1486-1496
    • Schmidt, C.1    Priemel, M.2    Kohler, T.3    Weusten, A.4    Muller, R.5    Amling, M.6    Eckstein, F.7
  • 27
    • 28144448363 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors promote osteoblast maturation
    • DOI 10.1359/JBMR.050813
    • Schroeder TM, Westendorf JJ. (2005) Histone deacetylase inhibitors promote osteoblast maturation. J Bone Miner Res 20:2254-2263. (Pubitemid 41698788)
    • (2005) Journal of Bone and Mineral Research , vol.20 , Issue.12 , pp. 2254-2263
    • Schroeder, T.M.1    Westendorf, J.J.2
  • 29
    • 8844264414 scopus 로고    scopus 로고
    • Metabolic concerns associated with antiepileptic medications
    • Sheth RD. (2004) Metabolic concerns associated with antiepileptic medications. Neurology 63:S24-S29.
    • (2004) Neurology , vol.63
    • Sheth, R.D.1
  • 30
    • 0029815364 scopus 로고    scopus 로고
    • Increased bone resorption precedes increased bone formation in the ovariectomized rat
    • DOI 10.1007/s002239900098
    • Sims NA, Morris HA, Moore RJ, Durbridge TC. (1996) Increased bone resorption precedes increased bone formation in the ovariectomized rat. Calcif Tissue Int 59:121-127. (Pubitemid 26266277)
    • (1996) Calcified Tissue International , vol.59 , Issue.2 , pp. 121-127
    • Sims, N.A.1    Morris, H.A.2    Moore, R.J.3    Durbridge, T.C.4
  • 31
    • 0036139964 scopus 로고    scopus 로고
    • Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males
    • DOI 10.1016/S8756-3282(01)00643-3, PII S8756328201006433
    • Sims NA, Dupont S, Krust A, Clement-Lacroix P, Minet D, Resche-Rigon M, Gaillard-Kelly M, Baron R. (2002) Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males. Bone 30:18-25. (Pubitemid 34044296)
    • (2002) Bone , vol.30 , Issue.1 , pp. 18-25
    • Sims, N.A.1    Dupont, S.2    Krust, A.3    Clement-Lacroix, P.4    Minet, D.5    Resche-Rigon, M.6    Gaillard-Kelly, M.7    Baron, R.8
  • 34
    • 17644390924 scopus 로고    scopus 로고
    • Genetic variation in structure-function relationships for the inbred mouse lumbar vertebral body
    • Tommasini SM, Morgan TG, van der Meulen M, Jepsen KJ. (2005) Genetic variation in structure-function relationships for the inbred mouse lumbar vertebral body. J Bone Miner Res 20:817-827.
    • (2005) J Bone Miner Res , vol.20 , pp. 817-827
    • Tommasini, S.M.1    Morgan, T.G.2    Van Der Meulen, M.3    Jepsen, K.J.4
  • 36
    • 7944235860 scopus 로고    scopus 로고
    • Fracture risk associated with use of antiepileptic drugs
    • DOI 10.1111/j.0013-9580.2004.18804.x
    • Vestergaard P, Rejnmark L, Mosekilde L. (2004) Fracture risk associated with use of antiepileptic drugs. Epilepsia 45:1330-1337. (Pubitemid 39470036)
    • (2004) Epilepsia , vol.45 , Issue.11 , pp. 1330-1337
    • Vestergaard, P.1    Rejnmark, L.2    Mosekilde, L.3
  • 37
    • 0021238171 scopus 로고
    • Decreased serum ionized calcium and normal vitamin D metabolite levels with anticonvulsant drug treatment
    • Weinstein RS, Bryce GF, Sappington LJ, King DW, Gallagher BB. (1984) Decreased serum ionized calcium and normal vitamin D metabolite levels with anticonvulsant drug treatment. J Clin Endocrinol Metab 58:1003-1009.
    • (1984) J Clin Endocrinol Metab , vol.58 , pp. 1003-1009
    • Weinstein, R.S.1    Bryce, G.F.2    Sappington, L.J.3    King, D.W.4    Gallagher, B.B.5
  • 38
    • 0031679162 scopus 로고    scopus 로고
    • Evaluation of a rat model of valproate-induced obesity
    • Wolden-Hanson T, Gidal BE, Atkinson RL. (1998) Evaluation of a rat model of valproate-induced obesity. Pharmacotherapy 18(5):1075-1081.
    • (1998) Pharmacotherapy , vol.18 , Issue.5 , pp. 1075-1081
    • Wolden-Hanson, T.1    Gidal, B.E.2    Atkinson, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.