Partial intra-aortic occlusion improves perfusion deficits and infarct size following focal cerebral ischemia

Journal of Neuroimaging

Volumn 20, Issue 3, 2010, Pages 272-276

  Noor, Raza ^a   Wang, Chen Xu ^a   Todd, Kathryn ^b   Elliott, Cameron ^b   Wahr, Joyce ^c   Shuaib, Ashfaq ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c CoAxia Inc ^*  (United States)

Author keywords

aortic occlusion; infarction; Ischemia; stroke; tPA

Indexed keywords

GELATINASE B; TISSUE PLASMINOGEN ACTIVATOR;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA OCCLUSION; ARTICLE; BRAIN HEMORRHAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; ENZYME ACTIVATION; FOCAL CEREBRAL ISCHEMIA; HYPOTHESIS; MALE; NONHUMAN; PARTIAL INTRA AORTIC OCCLUSION; PROTEIN EXPRESSION; RAT; STROKE; ANALYSIS OF VARIANCE; ANIMAL; AORTA; BALLOON OCCLUSION; BRAIN; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANALYSIS OF VARIANCE; ANIMALS; AORTA; BALLOON OCCLUSION; BRAIN; BRAIN ISCHEMIA; MALE; MATRIX METALLOPROTEINASE 9; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77954638815     PISSN: 10512284     EISSN: 15526569     Source Type: Journal    
DOI: 10.1111/j.1552-6569.2009.00436.x     Document Type: Article

References (15)

1. Demaerschalk BM. Diagnosis and management of stroke (brain attack). Semin Neurol 2003 23 (3 241 252.
2. del Zoppo GJ, Poeck K, Pessin MS, et al. Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann Neurol 1992 32 (1 78 86.
3. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995 333 : 1581 1587.
4. Thomassen L, Bakke MJ. Endovascular reperfusion therapy in acute ischaemic stroke. Acta Neurol Scand Suppl 2007 187 : 22 29.
5. Albers GW, Easton JD, Sacco RL, et al. Antithrombotic and thrombolytic therapy for ischemic stroke. Chest 1998 114 (5 Suppl 683S 698S.
6. Thomassen L, Waje-Andreassen U, Naess H, et al. Doppler ultrasound and clinical findings in patients with acute ischemic stroke treated with intravenous thrombolysis. Eur J Neurol 2005 12 : 462 465.
7. Zangerle A, Kiechl S, Spiegel M, et al. Recanalization after thrombolysis in stroke patients: predictors and prognostic implications. Neurology 2007 68 : 39 44.
8. Grotta JC, Pettigrew LC, Allen S, et al. Baseline hemodynamic state and response to hemodilution in patients with acute cerebral ischemia. Stroke 1985 16 (5 790 795.
9. Rosen CL, Sekhar LN, Duong DH. Use of intra-aortic balloon pump counterpulsation for refractory symptomatic vasospasm. Acta Neurochir (Wien) 2000 142 (1 25 32.
10. Lylyk P, Vila JF, Miranda C, et al. Partial aortic obstruction improves cerebral perfusion and clinical symptoms in patients with symptomatic vasospasm. Neurol Res 2005 27 (Suppl 1 S129 S135.
11. Noor R, Wang C, Shuaib A. Effects of hyperthermia on infarct volume in embolic model of cerebral ischemia. Neurosci Lett 2003 349 (2 130 132.
12. Wang CX, Yang T, Shuaib A. An improved version of embolic model of brain ischemic injury in rat. J Neurosci Methods 2001 109 : 147 151.
13. Kelly MA, Shuaib A, Todd KG. Matrix metalloproteinase activation and blood-brain barrier breakdown following thrombolysis. Exp Neurol 2006 200 (1 38 49.
14. Uddin G, Wang CX, Shuaib A. Acetylsalicylic acid reduces perfusion deficit in ischemic injured brain in rats. Neuroreport 2003 14 : 1753 1755.
15. Wang S, Lee SR, Guo SZ, et al. Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes. Stroke 2006 37 (7 1910 1912.