Ketoconazole in the treatment of central serous chorioretinopathy: A pilot study

Acta Ophthalmologica

Volumn 88, Issue 5, 2010, Pages 576-581

  Golshahi, Azadeh ^a   Klingmüller, Dietrich ^a   Holz, Frank G ^a   Eter, Nicole ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

central serous chorioretinopathy; corticosteroids; CSC; CSCR; ketoconazole

Indexed keywords

KETOCONAZOLE;

ADULT; AGED; ARTICLE; CENTRAL SEROUS RETINOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG WITHDRAWAL; ERECTILE DYSFUNCTION; FEMALE; HUMAN; MALE; NAUSEA; OPTICAL COHERENCE TOMOGRAPHY; PILOT STUDY; PRIORITY JOURNAL; RETINA DETACHMENT; RETINA FLUORESCEIN ANGIOGRAPHY; RETINAL THICKNESS; RETROSPECTIVE STUDY; VISUAL ACUITY; VISUAL SYSTEM PARAMETERS;

ADULT; AGED; AGED, 80 AND OVER; ANTIFUNGAL AGENTS; CENTRAL SEROUS CHORIORETINOPATHY; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; KETOCONAZOLE; MALE; MIDDLE AGED; PILOT PROJECTS; RETINA; TOMOGRAPHY, OPTICAL COHERENCE; TREATMENT OUTCOME; VISUAL ACUITY;

EID: 77954630142     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2008.01467.x     Document Type: Article

References (47)

1. Abuel-Asrar AM (1997 Central serous chorioretinopathy complicating systemic corticosteroid therapy. Eur J Ophthalmol 7 : 297 300.
2. Baumal CR, Martidis A Truong SN (2004 Central serous chorioretinopathy associated with periocular corticosteroid injection treatment for HLA-B27-associated iritis. Arch Ophthalmol 122 : 926 928.
3. Bennett G (1955 Central serous retinopathy. Br J Ophthalmol 39 : 605 618.
4. Bouzas EA, Scott MH, Mastorakos G, Chrousos GP Kaiser-Kupfer MI (1993 Central serous chorioretinopathy in endogenous hypercortisolism. Arch Ophthalmol 111 : 1229 1233.
5. Bouzas EA, Philippe M Pournaras CJ (1999 Central serous chorioretinopathy complicating solar retinopathy treated with glucocorticoids. Graefes Arch Clin Exp Ophthalmol 237 : 166 168.
6. Bouzas EA, Karadimas P Pournaras CJ (2002 Central serous chorioretinopathy and glucocorticoids. Surv Ophthalmol 47 : 431 448.
7. Bujarborua D (2001 Longterm follow-up of idiopathic central serous chorioretinopathy without laser. Acta Ophthalmol Scand 79 : 417 421.
8. Carvalho-Recchia CA, Yannuzzi LA, Negrao S et al. (2002 Corticosteroids and central serous chorioretinopathy. Ophthalmology 109 : 1834 1837.
9. Chou SC Lin JD (2000 Longterm effects of ketoconazole in the treatment of residual or recurrent Cushing's disease. Endocr J 47 : 401 406.
10. Conrad R, Bodeewes I, Schilling G et al. (2000 Central serous chorioretinopathy and psychological stress. Ophthalmologe 97 : 527 531.
11. Deussen A, Sonntag M Vogel R (1993 L-arginin-derived nitric oxide: a major determinant of uveal blood flow. Exp Eye Res 57 : 129 134.
12. Dohrmann J, Lommatzsch A, Spital G Pauleikhoff D (2001 Die Pathogenese der zentralserösen Chorioretinopathie. Ophthalmologe 98 : 1069 1073.
13. Fernandez CF, Mendoza AJ Arevalo JF (2004 Central serous chorioretinopathy associated with topical dermal corticosteroids. Retina 24 : 471 474.
14. Garg SP, Dada T, Talwar D et al. (1997 Endogenous cortisol profile in patients with central serous chorioretinopathy. Br J Ophthalmol 81 : 962 964.
15. Gass JD (1967 Pathogenesis of disciform detachment of the neuroepithelium. Am J Ophthalmol 63 : 587 615.
16. Gelber GS Schatz H (1987 Loss of vision due to central serous chorioretinopathy following psychological stress. Am J Psychiatry 144 : 46 50.
17. Gill GN (1990 The adrenal gland. In : West JB (ed Best and Taylor's Physiological Basis of Medical Practice, Vol. 12.
18. Haimovici R, Gragudas ES, Duker JS, Sjaarda RN Eliott D (1997 Central serous chorioretinopathy associated with inhaled or intranasal corticosteroids. Ophthalmology 104 : 1653 1660.
19. Haimovici R, Rumelt S Melby J (2003 Endocrine abnormalities in patients with central serous chorioretinopathy. Ophthalmology 110 : 698 703.
20. Haimovici R, Koh S, Gagnon DR et al. (2004 Risk factors for central serous chorioretinopathy: a case-control study. Ophthalmology 111 : 244 249.
21. Harada T Harada K (1985 Six cases of central serous chorioretinopathy induced by systemic corticosteroid therapy. Doc Ophthalmol 60 : 37 44.
22. Jampol LM, Weinreb R Yannuzzi L (2002 Involvement of corticosteroids and catecholamines in the pathogenesis of central serous chorioretinopathy: a rationale for new treatment strategies. Ophthalmology 109 : 1765 1766.
23. Kapetanios AD, Donati G, Bouzas E et al. (1998 Serous central chorioretinopathy and endogenous hypercortisolism. Klin Monatsbl Augenheilkd 212 : 343 344.
24. Karadimas P, Kapetanios A Bouzas EA (2004 Central serous chorioretinopathy after local application of glucocorticoids for skin disorders. Arch Ophthalmol 122 : 784 786. (Pubitemid 38596264)
25. Lin JM Tsai YY (2001 Retinal pigment epithelial detachment in the fellow eye of a patient with unilateral central serous chorioretinopathy treated with steroid. Retina 21 : 377 379.
26. Mann RM, Riva CE, Stone RA et al. (1995 Nitric oxide and choroidal blood flow regulation. Invest Ophthalmol Vis Sci 36 : 925 930.
27. Meyerle CB, Freund KB, Bhatnagar P et al. (2007 Ketoconazole in the treatment of chronic idiopathic central serous chorioretinopathy. Retina 27 : 943 946.
28. Michael JC, Pak J, Pulido J de Venecia G (2003 Central serous chorioretinopathy associated with administration of sympathomimetic agents. Am J Ophthalmol 136 : 182 185.
29. Minckler D (1999 Acknowledging the importance of study design in the organization and quality of manuscripts. Ophthalmology 106 : 11 12.
30. Oikarinen AI, Uitto J Oikarinen J (1986 Glucocorticoid action on connective tissue: From molecular mechanisms to clinical practice. Med Biol 64 : 221 230.
31. Ozsoylu S, Strauss H Diamond LK (1962 Effects of corticosteroid on coagulation of the blood. Nature 195 : 1214 1215.
32. Polak BC, Baarsma GS Snyers B (1995 Diffuse retinal pigment epitheliopathy complicating systemic corticosteroid treatment. Br J Ophthalmol 79 : 922 925.
33. Prünte C Flammer J (1996 Choroidal capillary and venous congestion in central serous chorioretinopathy. Am J Ophthalmol 121 : 26 34. (Pubitemid 26026078)
34. Smith TJ (1984 Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts. Similar effects of glucocorticoid and thyroid hormones. J Clin Invest 74 : 2157 2163.
35. Spaide RF, Campeas L, Haas A, Yannuzzi LA et al. (1996a Central serous chorioretinopathy in younger and older adults. Ophthalmology 103 : 2070 2079.
36. Spaide RF, Hall L, Haas A et al. (1996b Indocyanine green videoangiography of older patients with central serous chorioretinopathy. Retina 16 : 203 213.
37. Spitznas M (1986 Pathogenesis of central serous retinopathy: a new working hypothesis. Graefes Arch Clin Exp Ophthalmol 224 : 321 332.
38. Spraul CW, Lang GE Lang GK (1997 Central serous chorioretinopathy in systemic therapy with corticosteroids. Ophthalmologe 94 : 392 396.
39. Taban M, Boyer DS, Thomas EL Taban M (2004 Chronic central serous chorioretinopathy: photodynamic therapy. Am J Ophthalmol 137 : 1073 1080.
40. Thoelen AM, Bernasconi PP, Schmid C Messmer EP (2000 Central serous chorioretinopathy associated with a carcinoma of the adrenal cortex. Retina 20 : 98 99.
41. Tittl MK, Spaide RF, Wong D et al. (1999 Systemic findings associated with central serous chorioretinopathy. Am J Ophthalmol 28 : 63 68.
42. Wakakura M, Song E Ishikawa S (1997 Corticosteroid-induced central serous chorioretinopathy. Jpn J Ophthalmol 41 : 180 185.
43. Wang M, Munch IC, Hasler PW, Prünte C Larsen M (2008 Central serous chorioretinopathy. Acta Ophthalmol 86 : 126 145.
44. Winquist EW, Laskey J, Crump M, Khamsi F Shepherd FA (1995 Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. J Clin Oncol 13 : 157 164.
45. Worrall NK, Misko TP, Sullivan PM, Hui JJ, Rodi CP Ferguson TB (1996 Corticosteroids inhibit expression of inducible nitric oxide synthase during acute cardiac allograft rejection. Transplantation 61 : 324 328.
46. Wynn PA (2001 Idiopathic central serous chorioretinopathy: a physical complication of stress? Occup Med 51 : 139 140.
47. Yannuzzi LA (1987 Type-A behaviour and central serous chorioretinopathy. Retina 7 : 111 131.