Ex vivo organ culture of adipose tissue for in situ mobilization of adipose-derived stem cells and defining the stem cell niche

Journal of Cellular Physiology

Volumn 224, Issue 3, 2010, Pages 807-816

  Yang, Young Il ^a,b   Kim, Hyeong In ^b   Choi, Min Young ^b   Son, Sung Hee ^a   Seo, Min Jeong ^b   Seo, Ji Yeon ^b   Jang, Won Hee ^a   Youn, Young Chul ^a   Choi, Kang Joo ^a   Cheong, Soon Ho ^a,b   Shelby, Jane ^b  

^a Inje University College of Medicine   (South Korea)

^b Inje University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD146 ANTIGEN; CD31 ANTIGEN; CD34 ANTIGEN; CELL SURFACE MARKER; FIBRIN; UROKINASE;

ADIPOCYTE; ADIPOSE DERIVED STEM CELL; ADIPOSE TISSUE; ADULT; ARTICLE; CAPILLARY ENDOTHELIUM; CAPILLARY WALL; CELL DIFFERENTIATION; CELL DIVISION; CELL GROWTH; CELL LINEAGE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENCAPSULATION; ENDOTHELIUM CELL; EX VIVO STUDY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INTERSTITIUM; MESENCHYMAL STEM CELL; ORGAN CULTURE; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; STEM CELL EXPANSION; STEM CELL MOBILIZATION; STROMA CELL; TISSUE CULTURE;

ADIPOSE TISSUE; ADULT; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; FIBRIN; HUMANS; MIDDLE AGED; ORGAN CULTURE TECHNIQUES; PHENOTYPE; STEM CELL NICHE; STEM CELLS; STROMAL CELLS; TISSUE SCAFFOLDS;

EID: 77954611591     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22188     Document Type: Article

References (41)

1. Abedin M, Tintut Y, Demer LL. 2004. Mesenchymal stem cells and the artery wall. Circ Res 95: 671-676.
2. Amos PJ, Shang H, Bailey AM, Taylor A, Katz AJ, Peirce SM. 2008. IFATS Collection: The role of human adipose-derived stromal cells in inflammatory microvascular remodeling and evidence of a perivascular phenotype. Stem Cells 26:2682-2690.
3. Anderer U, Libera J. 2002. In vitro engineering of human autogenous cartilage. J Bone Miner Res 17:1420-1429.
4. Bensaid W, Triffitt JT, Blanchat C, Oudina K, Sedel L, Petite H. 2003. A biodegradable fibrin scaffold for mesenchymal stem cell transplantation. Biomaterials 24:2497-2502. (Pubitemid 36407666)
5. Bryant DM, Mostov KE. 2008. From cells to organs: Building polarized tissue. Nat Rev Mol Cell Biol 9:887-901.
6. Covasa DT, Panepuccia RA, Fontesa AM, Silva WA, Jr., Orellana MD, Freitas MC, Neder L, Santos AR, Peres LC, Jamur MC, Zago MA. 2008. Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts. Exp Hematol 36:642-654.
7. Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS, Andriolo G, Sun B, Zheng B, Zhang L, Norotte C, Teng PN, Traas J, Schugar R, Deasy BM, Badylak S, Bühring HJ, Giacobino JP, Lazzari L, Huard J, Péault B. 2008. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 3:301-313.
8. da Silva Meirelles L, Caplan AI, Nardi NB. 2008. In search of the in vivo identity of mesenchymal stem cells. Stem Cells 26:2287-2299.
9. Dellavalle A, Sampaolesi M, Tonlorenzi R, Tagliafico E, Sacchetti B, Perani L, Innocenzi A, Galvez BG, MessinaG, Morosetti R, Li S, BelicchiM, Peretti G, Chamberlain JS, Wright WE, Torrente Y, Ferrari S, Bianco P, Cossu G. 2007. Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. Nat Cell Biol 9:255-267.
10. DomiciniM, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop DJ, Horwitz E. 2006. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8:315-317.
11. Farrington-Rock C, Crofts NJ, Doherty MJ, Ashton BA, Griffin-Jones C, Canfield AE. 2004. Chondrogenic and adipogenic potential of microvascular pericytes. Circulation 110:2226-2232. (Pubitemid 39372506)
12. Fried SK, Moustaid-Moussa N. 2001. Culture of adipose tissue and isolated adipocytes. Methods Mol Biol 155:197-212.
13. Gesta S, Lolmede K, Daviaud D, Berlan M, Bouloumié A, Lafontan M, Valet P, Saulnier-Blache JS. 2003. Culture of human adipose tissue explants leads to profound alteration of adipocyte gene expression. Horm Metab Res 35:158-163. (Pubitemid 36577857)
14. Gimble JM, Katz AJ, Bunnell BA. 2007. Adipose-derived stem cells for regenerative medicine. Circ Res 100:1249-1260. (Pubitemid 46742916)
15. Gomillion CT, Burg KJ. 2006. Stem cells and adipose tissue engineering. Biomaterials 27:6052-6063. (Pubitemid 44414978)
16. Gronthos S, Franklin DM, Leddy HA, Robey PG, Storms RW, Gimble JM. 2001. Surface protein characterization of human adipose tissue-derived stromal cells. J Cell Physiol 189:54-63. (Pubitemid 32830423)
17. Katz AJ, Tholpady A, Tholpady SS, Shang H, Ogle RC. 2005. Cell surface and transcriptional characterization of human adipose-derived adherent stromal (hADAS) cells. Stem Cells 23:412-423. (Pubitemid 40404460)
18. Laurens N, Koolwijk P, de Matt PM. 2006. Fibrin structure and wound healing. J Thromb Haemost 4:932-939.
19. Li L, Xie T. 2005. Stem cell niche: Structure and functions. Annu Rev Cell Dev Biol 21:605-631. (Pubitemid 41740648)
20. Li Q, Yu Y, Bischoff J, Mulliken JB,Olsen BR. 2003. Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin. J Pathol 201:296-302. (Pubitemid 37258941)
21. Lin G, Garcia M, Ning H, Banie L, Guo YL, Lue TF, Lin CS. 2008. Defining stem and progenitor cells within adipose tissue. Stem Cells Dev 17:1053-1063.
22. Liu H, Collins SF, Suggs LJ. 2006. Three-dimensional culture for expansion and differentiation of mouse embryonic stem cells. Biomaterials 27:6004-6014. (Pubitemid 44414972)
23. Middleton J, Americh L, Gayon R, Julien D, Mansat M, Mansat P, Anract P, Cantagrel A, Cattan P, Reimund JM, Aguilar L, Amalric F, Girard JP. 2005. A comparative study of endothelial cell markers expressed in chronically inflamed human tissues: MECA-79, Duffy antigen receptor for chemokines, von Willebrand factor, CD31, CD34, CD105 and CD146. J Pathol 206:260-268.
24. Mitchell JB, McIntosh K, Zvonic S, Garrett S, Floyd ZE, Kloster A, Di Halvorsen Y, Storms RW, Goh B, Kilroy G, Wu X, Gimble JM. 2006. Immunophenotype of human adipose-derived cells: Temporal changes in stromal-associated and stem cell-associated markers. Stem Cells 24:376-385.
25. Miyazaki T, Kitagawa Y, Toriyama K, Kobori M, Torii S. 2005. Isolation of two human fibroblastic cell populations with multiple but distinct potential of mesenchymal differentiation by ceiling culture of mature fat cells from subcutaneous adipose tissue. Differentiation 73:69-78. (Pubitemid 41583379)
26. Oedayrajsingh-Varma M, van Ham S, Knippenberg M, Oedayrajsingh-Varma MJ, van Ham SM, Knippenberg M, Helder MN, Klein-Nulend J, Schouten TE, Ritt MJ, van Milligen FJ. 2006. Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure. Cytotherapy 8:166-177. (Pubitemid 43675203)
27. Ootani A, Li X, Sangiorgi E, Sangiorgi E, Ho QT, Ueno H, Toda S, Sugihara H, Fujimoto K, Weissman IL, Capecchi MR, Kuo CJ. 2009. Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. Nat Med 15:701-706.
28. Papini S, Rosellini A, Nardi M, Giannarini C, Revoltella RP. 2005. Selective growth and expansion of human corneal epithelial basal stem cells in a three-dimensional-organ culture. Differentiaiton 73:61-68. (Pubitemid 41583378)
29. Park SK, Jang WH, Yang YI. 2009. Expression of pro-angiogenic cytokines and their inhibition by dexamethasone in an ex vivo model of nasal polyp. Biochem Biophys Res Commun 379:255-260.
30. Patrick CW. 2000. Adipose tissue engineering: The future of breast and soft tissue reconstruction following tumor resection. Semin Surg Oncol 19:302-311.
31. Pluskota E, Soloviev DA, Plow EF. 2003. Convergence of the adhesive and fibrinolytic systems: Recognition of urokinase by integrin aMb2 as well as by the urokinase receptor regulates cell adhesion and migration. Blood 101:1582-1590.
32. Richardson RL, Hausman GJ, Campion DR. 1982. Response of pericytes to thermal lesion in the inguinal fat pad of 10-day-old rats. Acta Anat (Basel) 114:41-57.
33. Saccheti B, Funari A, Michienzi S, Di Cesare S, Piersanti S, Saggio I, Tagliafico E, Ferrari S, Robey PG, Riminucci M, Bianco P. 2007. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 131:324-336.
34. Schaffler A, Buchler C. 2007. Concise review: Adipose tissue-derived stromal cells - Basic and clinical implications for novel cell-based therapies. Stem Cells 25:818-827.
35. Schwab KE, Gargett CE. 2007. Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium. Hum Reprod 22:2903-2911.
36. Slavin BG, Elias JJ. 1970. Morphologic changes in white and brown adipose tissue by insulin, thyroxin and cortisol in organ culture. Anat Rec 167:213-218.
37. Sugihara H, Funatsumaru S, Yonemitsu N, Miyabara S, Toda S, Hikichi Y. 1989. A simple culture method of fat cells from mature fat tissue fragments. J Lipid Res 30:1987-1995.
38. Traktuev DO, Merfeld-Clauss S, Li J, Kolonin M, Arap W, Pasqualini R, Johnstone BH, March KL. 2008. A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res 102:77-85.
39. Volkmer E, Drosse I, Otto S, Stangelmayer A, Stengele M, Kallukalam BC, Mutschler W, Schieker M. 2008. Hypoxia in static and dynamic 3D culture systems for tissue engineering of bone. Tissue Eng Part A 14:1331-1340.
40. Yamada KM, Cukierman E. 2007. Modeling tissue morphogenesis and cancer in 3D. Cell. 130:601-610.
41. Zannettino ACW, Paton S, Arthur A, Khor F, Itescu S, Gimble JM, Gronthos S. 2008. Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. J Cell Physiol 214:413-421.