Effects of oligomeric grape seed proanthocyanidins on isoproterenol-induced cardiac remodeling in rats

Yaoxue Xuebao

Volumn 45, Issue 5, 2010, Pages 565-570

  Zuo, You Mei ^a   Gao, Shan ^a   Cao, Jian Fei ^a   Liu, Xiao Yu ^a   Yu, Hong Jian ^b   Zhang, Ye ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Tianjin Jianfeng Natural Product R and D Co Ltd   (China)

Author keywords

Cardiac remodeling; Isoproterenol; Oligomeric grape seed proanthocyanidins; Oxidative stress

Indexed keywords

GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROXYPROLINE; ISOPRENALINE; MALONALDEHYDE; PROANTHOCYANIDIN DERIVATIVE; SUPEROXIDE; THIOBARBITURIC ACID; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; GRAPE; HEART FUNCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART RATE; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HISTOLOGY; NONHUMAN; OXIDATIVE STRESS; RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; ANTIOXIDANTS; GRAPE SEED EXTRACT; HEART RATE; HYDROXYPROLINE; ISOPROTERENOL; MALE; MALONDIALDEHYDE; MYOCARDIUM; ORGAN SIZE; PLANTS, MEDICINAL; PROANTHOCYANIDINS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE; VENTRICULAR REMODELING; VITIS;

EID: 77954583287     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Willenheimer R. Left ventricular remodelling and dysfunction. Can the process be prevented? [J]. Int J Cardiol, 2000, 72: 143-150.
2. Gradman AH, Alfayoumi F. From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease [J]. Prog Cardiovasc Dis, 2006, 48: 326-341.
3. Hon M, Nishida K. Oxidative stress and left ventricular remodeling after myocardial infarction [J]. Cardiovasc Res, 2009, 81: 457-464.
4. Takimoto E, Kass DA. Role of oxidative stress in cardiac hypertrophy and remodeling [J]. Hypertension, 2007, 49: 241-248.
5. Bagchi D, Bagchi M, Stohs SJ, et al. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention [J]. Toxicology, 2000, 148: 187-197. (Pubitemid 30621359)
6. Bagchi D, Garg A, Krohn RL, et al. Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro [J]. Res Commun Mol Pathol Pharmacol, 1997, 95: 179-189. (Pubitemid 27147562)
7. Karthikeyan K, Bai BR, Devaraj SN. Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats [J]. Int J Cardiol, 2007, 115: 326-333.
8. Mikusová A, Králová E, Tylková L, et al. Myocardial remodelling induced by repeated low doses of isoproterenol [J]. Can J Physiol Pharmacol, 2009, 87: 641-651.
9. Zhao HP, Hong Y, Xie JD, et al. Effect of berberine on left ventricular remodeling in renovascular hypertensive rats [J]. Acta Pharm Sin, 2007, 42: 336-341.
10. Fan GC, Yuan Q, Song G, et al. Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1 [J]. Circ Res, 2006, 99: 1233-1242.
11. Osadchii OE, Norton GR, McKechnie R, et al. Cardiac dilatation and pump dysfunction without intrinsic myocardial systolic failure following chronic β-adrenoreceptor activation [J]. Am J Physiol Heart Circ Physiol, 2007, 292: H1898-H1905.
12. Goyal SN, Arora S, Sharma AK, et al. Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastructural alterations in isoproterenol-induced cardiotoxicity in rats [J]. Phytomedicine, 2010, 17: 227-232.
13. Zhao W, Zhao D, Yan R, et al. Cardiac oxidative stress and remodeling following infarction: role of NADPH oxidase [J]. Cardiovasc Pathol, 2009, 18: 156-166.
14. Zhang GX, Ohmori K, Nagai Y, et al. Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice [J]. J Mol Cell Cardiol, 2007, 42: 804-811. (Pubitemid 46527601)
15. Upaganlawar A, Gandhi C, Balaraman R. Effect of green tea and vitamin E combination in isoproterenol induced myocardial infarction in rats [J]. Plant Foods Hum Nutr, 2009, 64: 75-80.
16. Rajadurai M, Stanely Mainzen Prince P. Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidences [J]. Toxicology, 2006, 228: 259-268.
17. Tang LQ, Wei W, Chen LM. Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats [J]. J Ethnopharmacol, 2006, 108: 109-115.