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Volumn 202, Issue 2, 2010, Pages 291-301

Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV

(12)  Crain, Marilyn J a   Chernoff, Miriam C b   Oleske, James M d   Brogly, Susan B b   Malee, Kathleen M e   Borum, Peggy R f   Meyer, William A g   Mitchell, Wendy G i   Moye, John H h   Ford Chatterton, Heather M j   Van Dyke, Russell B k   Seage, George R b,c  


Author keywords

[No Author keywords available]

Indexed keywords

DIDANOSINE; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 77954577898     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/653497     Document Type: Article
Times cited : (26)

References (48)
  • 1
    • 17944377621 scopus 로고    scopus 로고
    • Maternal and infant factors associated with failure to thrive in children with vertically transmitted human immunodeficiency virus-1 infection: The prospective, P2C2 human immunodeficiency virus multicenter study
    • Miller TL, Easley KA, Zhang W, et al. Maternal and infant factors associated with failure to thrive in children with vertically transmitted human immunodeficiency virus-1 infection: the prospective, P2C2 human immunodeficiency virus multicenter study. Pediatrics 2001; 108: 1287-1296.
    • (2001) Pediatrics , vol.108 , pp. 1287-1296
    • Miller, T.L.1    Easley, K.A.2    Zhang, W.3
  • 2
    • 10744226254 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion and respiratory chain enzyme deficiencies are present in peripheral blood mononuclear cells of HIV-infected patients with HAART-related lipodystrophy
    • Miro O, Lopez S, Pedrol E, et al. Mitochondrial DNA depletion and respiratory chain enzyme deficiencies are present in peripheral blood mononuclear cells of HIV-infected patients with HAART-related lipodystrophy. Antivir Ther 2003; 8:333-338.
    • (2003) Antivir Ther , vol.8 , pp. 333-338
    • Miro, O.1    Lopez, S.2    Pedrol, E.3
  • 3
    • 4944235388 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy (HAART)-associated lactic acidosis: In vitro effects of combination of nucleoside analogues and protease inhibitors on mitochondrial function and lactic acid production
    • Nerurkar PV, Pearson L, Frank JE, Yanagihara R, Nerurkar VR. Highly active antiretroviral therapy (HAART)-associated lactic acidosis: in vitro effects of combination of nucleoside analogues and protease inhibitors on mitochondrial function and lactic acid production. Cell Mol Biol (Noisy-le-grand) 2003; 49:1205-1211.
    • (2003) Cell Mol Biol (Noisy-le-grand) , vol.49 , pp. 1205-1211
    • Nerurkar, P.V.1    Pearson, L.2    Frank, J.E.3    Yanagihara, R.4    Nerurkar, V.R.5
  • 4
    • 33745913329 scopus 로고    scopus 로고
    • Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIVinfected individuals
    • Cherry CL, Nolan D, James IR, et al. Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIVinfected individuals. J Acquir Immune Defic Syndr 2006; 42:435-440.
    • (2006) J Acquir Immune Defic Syndr , vol.42 , pp. 435-440
    • Cherry, C.L.1    Nolan, D.2    James, I.R.3
  • 5
    • 20844453407 scopus 로고    scopus 로고
    • Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals
    • Miro O, Lopez S, Martinez E, et al. Mitochondrial effects of HIV infection on the peripheral blood mononuclear cells of HIV-infected patients who were never treated with antiretrovirals. Clin Infect Dis 2004; 39:710-716.
    • (2004) Clin Infect Dis , vol.39 , pp. 710-716
    • Miro, O.1    Lopez, S.2    Martinez, E.3
  • 6
    • 0344236412 scopus 로고    scopus 로고
    • Genetic Features of Mitochondrial Respiratory Chain Disorders
    • DOI 10.1097/01.ASN.0000095481.24091.C9
    • Rotig A, Munnich A. Genetic features of mitochondrial respiratory chain disorders. J Am Soc Nephrol 2003; 14:2995-3007. (Pubitemid 37509278)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.12 , pp. 2995-3007
    • Rotig, A.1    Munnich, A.2
  • 7
    • 0037387554 scopus 로고    scopus 로고
    • Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine
    • Claessens Y-E, Cariou A, Monchi M, et al. Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine. Crit Care Med 2003; 31:1042-1047.
    • (2003) Crit Care Med , vol.31 , pp. 1042-1047
    • Claessens, Y.-E.1    Cariou, A.2    Monchi, M.3
  • 8
    • 0034956801 scopus 로고    scopus 로고
    • Epidemiology and treatment of mitochondrial disorders
    • Chinnery PF, Turnbull DM. Epidemiology and treatment of mitochondrial disorders. Am J Med Genet 2001; 106:94-101.
    • (2001) Am J Med Genet , vol.106 , pp. 94-101
    • Chinnery, P.F.1    Turnbull, D.M.2
  • 9
    • 9244249624 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in AIDS and its treatment
    • Gerschenson M, Brinkman K. Mitochondrial dysfunction in AIDS and its treatment. Mitochondrion 2004; 4:763-777.
    • (2004) Mitochondrion , vol.4 , pp. 763-777
    • Gerschenson, M.1    Brinkman, K.2
  • 10
    • 33845214020 scopus 로고    scopus 로고
    • Toward a pharmacogenetic understanding of nucleotide and nucleoside analogue toxicity
    • Hulgan T, Haas DW. Toward a pharmacogenetic understanding of nucleotide and nucleoside analogue toxicity. J Infect Dis 2006; 194: 1471-1474.
    • (2006) J Infect Dis , vol.194 , pp. 1471-1474
    • Hulgan, T.1    Haas, D.W.2
  • 11
    • 29144452191 scopus 로고    scopus 로고
    • Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: An adult AIDS clinical trials group study
    • Hulgan T, Haas DW, Haines JL, et al. Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. AIDS 2005; 19:1341-1349.
    • (2005) AIDS , vol.19 , pp. 1341-1349
    • Hulgan, T.1    Haas, D.W.2    Haines, J.L.3
  • 12
    • 34248669576 scopus 로고    scopus 로고
    • Molecular genetic and clinical aspects of mitochondrial disorders in childhood
    • Moslemi AR, Darin N. Molecular genetic and clinical aspects of mitochondrial disorders in childhood. Mitochondrion 2007; 7:241-252.
    • (2007) Mitochondrion , vol.7 , pp. 241-252
    • Moslemi, A.R.1    Darin, N.2
  • 13
    • 0037459945 scopus 로고    scopus 로고
    • A model of the nuclear control of mitochondrial DNA replication
    • Capps GJ, Samuels DC, Chinnery PF. A model of the nuclear control of mitochondrial DNA replication. J Theor Biol 2003; 221:565-583.
    • (2003) J Theor Biol , vol.221 , pp. 565-583
    • Capps, G.J.1    Samuels, D.C.2    Chinnery, P.F.3
  • 14
    • 0346995096 scopus 로고    scopus 로고
    • Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase
    • Lee H, Hanes J, Johnson KA. Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase. Biochemistry 2003; 42:14711-14719.
    • (2003) Biochemistry , vol.42 , pp. 14711-14719
    • Lee, H.1    Hanes, J.2    Johnson, K.A.3
  • 15
    • 1342310769 scopus 로고    scopus 로고
    • Antiretroviral nucleoside and nucleotide analogues and mitochondria
    • Cossarizza A, Moyle G. Antiretroviral nucleoside and nucleotide analogues and mitochondria. AIDS 2004; 18:137-151.
    • (2004) AIDS , vol.18 , pp. 137-151
    • Cossarizza, A.1    Moyle, G.2
  • 16
    • 0037045058 scopus 로고    scopus 로고
    • Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors
    • Walker UA, Setzer B, Venhoff N. Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors. AIDS 2002; 16:2165-2173.
    • (2002) AIDS , vol.16 , pp. 2165-2173
    • Walker, U.A.1    Setzer, B.2    Venhoff, N.3
  • 17
    • 33846844983 scopus 로고    scopus 로고
    • Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy
    • Chene G, Amellal B, Pedrono G, et al. Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy. AIDS Res Hum Retroviruses 2007; 23:54-61.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 54-61
    • Chene, G.1    Amellal, B.2    Pedrono, G.3
  • 18
    • 44949129640 scopus 로고    scopus 로고
    • Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy
    • McComsey GA, Kang M, Ross AC, et al. Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy. HIV Clin Trials 2008; 9:126-136.
    • (2008) HIV Clin Trials , vol.9 , pp. 126-136
    • McComsey, G.A.1    Kang, M.2    Ross, A.C.3
  • 19
    • 3242708621 scopus 로고    scopus 로고
    • Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudine
    • Lonergan JT, McComsey GA, Fisher RL, et al. Lack of recurrence of hyperlactatemia in HIV-infected patients switched from stavudine to abacavir or zidovudine. J Acquir Immune Defic Syndr 2004; 36: 935-942.
    • (2004) J Acquir Immune Defic Syndr , vol.36 , pp. 935-942
    • Lonergan, J.T.1    McComsey, G.A.2    Fisher, R.L.3
  • 20
    • 4544253103 scopus 로고    scopus 로고
    • Mitochondrial effects of antiretroviral therapies in asymptomatic patients
    • Lopez S, Miro O, Martinez E, et al. Mitochondrial effects of antiretroviral therapies in asymptomatic patients. Antivir Ther 2004; 9:47-55.
    • (2004) Antivir Ther , vol.9 , pp. 47-55
    • Lopez, S.1    Miro, O.2    Martinez, E.3
  • 21
    • 33748103186 scopus 로고    scopus 로고
    • Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients
    • Maagaard A, Holberg-Petersen M, Kollberg G, Oldfors A, Sandvik L, Bruun JN. Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients. Antivir Ther 2006; 11:601-608.
    • (2006) Antivir Ther , vol.11 , pp. 601-608
    • Maagaard, A.1    Holberg-Petersen, M.2    Kollberg, G.3    Oldfors, A.4    Sandvik, L.5    Bruun, J.N.6
  • 22
    • 9244219676 scopus 로고    scopus 로고
    • Role of mitochondria in HIV lipoatrophy: Insight into pathogenesis and potential therapies
    • McComsey GA, Walker UA. Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapies. Mitochondrion 2004; 4:111-118.
    • (2004) Mitochondrion , vol.4 , pp. 111-118
    • McComsey, G.A.1    Walker, U.A.2
  • 23
    • 1242341437 scopus 로고    scopus 로고
    • Greater and more rapid depletion of mitochondrial DNA in blood of patients treated with dual (zidovudine+didanosine or zidovudine+zalcitabine) vs. single (zidovudine) nucleoside reverse transcriptase inhibitors
    • Reiss P, Casula M, de Ronde A, Weverling GJ, Goudsmit J, Lange JM. Greater and more rapid depletion of mitochondrial DNA in blood of patients treated with dual (zidovudine+didanosine or zidovudine+zalcitabine) vs. single (zidovudine) nucleoside reverse transcriptase inhibitors. HIV Med 2004; 5:11-14
    • (2004) HIV Med , vol.5 , pp. 11-14
    • Reiss, P.1    Casula, M.2    De Ronde, A.3    Weverling, G.J.4    Goudsmit, J.5    Lange, J.M.6
  • 24
    • 36749058372 scopus 로고    scopus 로고
    • Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy
    • Saitoh A, Fenton T, Alvero C, Fletcher CV, Spector SA. Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy. Antimicrob Agents Chemother 2007; 51:4236-4242.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 4236-4242
    • Saitoh, A.1    Fenton, T.2    Alvero, C.3    Fletcher, C.V.4    Spector, S.A.5
  • 25
    • 48749084897 scopus 로고    scopus 로고
    • Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells
    • Saitoh A, Haas RH, Naviaux RK, Salva NG, Wong JK, Spector SA. Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells. Antimicrob Agents Chemother 2008; 52:2825-2830.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2825-2830
    • Saitoh, A.1    Haas, R.H.2    Naviaux, R.K.3    Salva, N.G.4    Wong, J.K.5    Spector, S.A.6
  • 26
    • 18244408516 scopus 로고    scopus 로고
    • Antiretroviral treatment in pediatric HIV infection in the United States: From clinical trials to clinical practice
    • Brogly S, Williams P, Seage GR III, Oleske JM, Van Dyke R, McIntosh K. Antiretroviral treatment in pediatric HIV infection in the United States: from clinical trials to clinical practice. JAMA 2005; 293:2213-2220.
    • (2005) JAMA , vol.293 , pp. 2213-2220
    • Brogly, S.1    Williams, P.2    Seage III, G.R.3    Oleske, J.M.4    Van Dyke, R.5    McIntosh, K.6
  • 27
    • 34247609876 scopus 로고    scopus 로고
    • In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children
    • Brogly SB, Ylitalo N, Mofenson LM, et al. In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children. AIDS 2007; 21:929-938.
    • (2007) AIDS , vol.21 , pp. 929-938
    • Brogly, S.B.1    Ylitalo, N.2    Mofenson, L.M.3
  • 28
    • 33646797733 scopus 로고    scopus 로고
    • In utero nucleoside reverse transcriptase inhibitor exposure and cancer in HIV-uninfected children: An update from the Pediatric AIDS Clinical Trials Group 219 and 219C cohorts
    • Brogly S, Williams P, Seage GR III, Van Dyke R. In utero nucleoside reverse transcriptase inhibitor exposure and cancer in HIV-uninfected children: an update from the Pediatric AIDS Clinical Trials Group 219 and 219C cohorts. J Acquir Immune Defic Syndr 2006; 41:535-536.
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 535-536
    • Brogly, S.1    Williams, P.2    Seage III, G.R.3    Van Dyke, R.4
  • 29
    • 33746100664 scopus 로고    scopus 로고
    • Incidence of opportunistic and other infections in HIV-infected children in the HAART era
    • Gona P, Van Dyke RB, Williams PL, et al. Incidence of opportunistic and other infections in HIV-infected children in the HAART era. JAMA 2006; 296:292-300.
    • (2006) JAMA , vol.296 , pp. 292-300
    • Gona, P.1    Van Dyke, R.B.2    Williams, P.L.3
  • 30
    • 0032991290 scopus 로고    scopus 로고
    • The Medical Dictionary for Regulatory Activities (MedDRA)
    • Brown EG, Wood L, Wood S. The Medical Dictionary for Regulatory Activities (MedDRA). Drug Saf 1999; 20:109-117.
    • (1999) Drug Saf , vol.20 , pp. 109-117
    • Brown, E.G.1    Wood, L.2    Wood, S.3
  • 31
    • 0036300273 scopus 로고    scopus 로고
    • Effects of coding dictionary on signal generation: A consideration of use of MedDRA compared with WHO-ART
    • Brown EG. Effects of coding dictionary on signal generation: a consideration of use of MedDRA compared with WHO-ART. Drug Saf 2002; 25:445-452.
    • (2002) Drug Saf , vol.25 , pp. 445-452
    • Brown, E.G.1
  • 33
    • 0037069274 scopus 로고    scopus 로고
    • Mitochondrial disorders: A proposal for consensus diagnostic criteria in infants and children
    • Wolf NI, Smeitink JA. Mitochondrial disorders: a proposal for consensus diagnostic criteria in infants and children. Neurology 2002; 59: 1402-1405.
    • (2002) Neurology , vol.59 , pp. 1402-1405
    • Wolf, N.I.1    Smeitink, J.A.2
  • 34
    • 0000771140 scopus 로고    scopus 로고
    • 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age
    • Caldwell B, Oxtoby M, Simonds RJ, Lindegren ML, Rogers M. 1994 Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. MMWR 1994; 43:1-10.
    • MMWR , vol.1994 , Issue.43 , pp. 1-10
    • Caldwell, B.1    Oxtoby, M.2    Simonds, R.J.3    Lindegren, M.L.4    Rogers, M.5
  • 35
    • 0042266280 scopus 로고    scopus 로고
    • Minimum birth prevalence of mitochondrial respiratory chain disorders in children
    • Skladal D, Halliday J, Thorburn DR. Minimum birth prevalence of mitochondrial respiratory chain disorders in children. Brain 2003; 126: 1905-1912.
    • (2003) Brain , vol.126 , pp. 1905-1912
    • Skladal, D.1    Halliday, J.2    Thorburn, D.R.3
  • 36
    • 39049156470 scopus 로고    scopus 로고
    • Prevalence of mitochondrial DNA disease in adults
    • Schaefer AM, McFarland R, Blakely EL, et al. Prevalence of mitochondrial DNA disease in adults. Ann Neurol 2008; 63:35-39.
    • (2008) Ann Neurol , vol.63 , pp. 35-39
    • Schaefer, A.M.1    McFarland, R.2    Blakely, E.L.3
  • 37
    • 14244259670 scopus 로고    scopus 로고
    • Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease
    • Scaglia F, Towbin JA, Craigen WJ, et al. Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease. Pediatrics 2004; 114:925-931.
    • (2004) Pediatrics , vol.114 , pp. 925-931
    • Scaglia, F.1    Towbin, J.A.2    Craigen, W.J.3
  • 38
    • 0141923809 scopus 로고    scopus 로고
    • The clinical spectrum of mitochondrial disease in 75 pediatric patients
    • Skladal D, Sudmeier C, Konstantopoulou V, et al. The clinical spectrum of mitochondrial disease in 75 pediatric patients. Clin Pediatr (Phila) 2003; 42:703-710.
    • (2003) Clin Pediatr (Phila) , vol.42 , pp. 703-710
    • Skladal, D.1    Sudmeier, C.2    Konstantopoulou, V.3
  • 40
    • 34250644231 scopus 로고    scopus 로고
    • Mechanisms of antiretroviral therapy-induced mitochondrial dysfunction
    • Cote HC. Mechanisms of antiretroviral therapy-induced mitochondrial dysfunction. Curr Opin HIV AIDS 2007; 2:253-260.
    • (2007) Curr Opin HIV AIDS , vol.2 , pp. 253-260
    • Cote, H.C.1
  • 41
    • 0036235237 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: What is the evidence?
    • Dagan T, Sable C, Bray J, Gerschenson M. Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence? Mitochondrion 2002; 1:397-412.
    • (2002) Mitochondrion , vol.1 , pp. 397-412
    • Dagan, T.1    Sable, C.2    Bray, J.3    Gerschenson, M.4
  • 42
    • 0242363266 scopus 로고    scopus 로고
    • Mitochondrial toxicity of NRTI antiviral rugs: An integrated cellular perspective
    • Lewis W, Day BJ, Copeland WC. Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective. Nat Rev Drug Discov 2003; 2:812-822.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 812-822
    • Lewis, W.1    Day, B.J.2    Copeland, W.C.3
  • 43
    • 0041412840 scopus 로고    scopus 로고
    • Factors associ ated with mitochondrial dysfunction in circulating peripheral blood lymphocytes from HIV-infected people
    • Polo R, Martinez S, Madrigal P, Gonzalez-Munoz M. Factors associ ated with mitochondrial dysfunction in circulating peripheral blood lymphocytes from HIV-infected people. J Acquir Immune Defic Syndr 2003; 34:32-36.
    • (2003) J Acquir Immune Defic Syndr , vol.34 , pp. 32-36
    • Polo, R.1    Martinez, S.2    Madrigal, P.3    Gonzalez-Munoz, M.4
  • 44
    • 33747605338 scopus 로고    scopus 로고
    • Current concepts in the diagnosis and management of metabolic complications of HIV infection and its therapy
    • Wohl DA, McComsey G, Tebas P, et al. Current concepts in the diagnosis and management of metabolic complications of HIV infection and its therapy. Clin Infect Dis 2006; 43:645-653.
    • (2006) Clin Infect Dis , vol.43 , pp. 645-653
    • Wohl, D.A.1    McComsey, G.2    Tebas, P.3
  • 45
    • 33745067485 scopus 로고    scopus 로고
    • Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: Evidence supporting the DNA pol gamma hypothesis
    • LewisW, Kohler JJ, Hosseini SH, et al. Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis. AIDS 2006; 20:675-684.
    • (2006) AIDS , vol.20 , pp. 675-684
    • Lewis, W.1    Kohler, J.J.2    Hosseini, S.H.3
  • 46
    • 24044496607 scopus 로고    scopus 로고
    • Mitochondrial DNA levels of peripheral blood mononuclear cells and subcutaneous adipose tissue from thigh, fat and abdomen of HIV-1 seropositive and negative individuals
    • Gerschenson M, Shiramizu B, LiButti DE, Shikuma CM. Mitochondrial DNA levels of peripheral blood mononuclear cells and subcutaneous adipose tissue from thigh, fat and abdomen of HIV-1 seropositive and negative individuals. Antivir Ther 2005; 10(suppl 2):M83-M89.
    • (2005) Antivir Ther , vol.10 , Issue.SUPPL. 2
    • Gerschenson, M.1    Shiramizu, B.2    LiButti, D.E.3    Shikuma, C.M.4
  • 47
    • 33748028820 scopus 로고    scopus 로고
    • Changes in body composition and mitochondrial nucleic acid content in patients switched from failed nucleoside analogue therapy to ritonavir-boosted indinavir and efavirenz
    • Boyd MA, Carr A, Ruxrungtham K, et al. Changes in body composition and mitochondrial nucleic acid content in patients switched from failed nucleoside analogue therapy to ritonavir-boosted indinavir and efavirenz. J Infect Dis 2006; 194:642-650.
    • (2006) J Infect Dis , vol.194 , pp. 642-650
    • Boyd, M.A.1    Carr, A.2    Ruxrungtham, K.3
  • 48
    • 0036174438 scopus 로고    scopus 로고
    • Assessment of mitochondrial toxicity in human cells treated with tenofovir: Comparison with other nucleoside reverse transcriptase inhibitors
    • DOI 10.1128/AAC.46.3.716-723.2002
    • Birkus G, Hitchcock MJ, Cihlar T. Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors. Antimicrob Agents Chemother 2002; 46:716-723. (Pubitemid 34157656)
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , Issue.3 , pp. 716-723
    • Birkus, G.1    Hitchcock, M.J.M.2    Cihlar, T.3


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