Does glomerular hyperfiltration in pregnancy damage the kidney in women with more parities?

International Urology and Nephrology

Volumn 41, Issue 4, 2009, Pages 927-932

  Gumus, Ilknur Inegol ^a   Uz, Ebru ^a   Bavbek, Nuket ^a   Kargili, Ayse ^a   Yanik, Burcu ^a   Turgut, Faruk Hilmi ^a   Akcay, Ali ^a   Turhan, Nilgun Ozturk ^a  

^a FATIH UNIVERSITY MEDICAL SCHOOL   (Turkey)

Author keywords

Glomerular hyperfiltration; Kidney; Parity; Pregnancy

Indexed keywords

CREATININE; UREA; URIC ACID;

ADULT; AGE; ARTICLE; BODY MASS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEMOGRAPHY; FEMALE; GLOMERULUS FILTRATION; HUMAN; KIDNEY INJURY; LABORATORY TEST; MAJOR CLINICAL STUDY; MULTIPARA; NULLIPARA; PARITY; PREGNANCY; RENAL PROTECTION; UREA BLOOD LEVEL;

ADULT; AGED; ANALYSIS OF VARIANCE; BODY MASS INDEX; COHORT STUDIES; CONFIDENCE INTERVALS; CREATININE; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; MIDDLE AGED; PARITY; PREGNANCY; PREGNANCY COMPLICATIONS; RISK FACTORS; SENSITIVITY AND SPECIFICITY; UREA; URIC ACID; URINALYSIS;

EID: 77954563567     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11255-009-9586-1     Document Type: Article

References (31)

1. Levine DZ (2006) Hyperfiltration, nitric oxide, and diabetic nephropathy. Curr Hypertens Rep 8:153-157. doi: 10. 1007/s11906-006-0012-0
2. Sebekova K, Klassen A, Bahner U, Heidland A (2004) Overweight and obesity-risk factors in the development and progression of renal disease. Vnitr Lek 50:544-549 (Pubitemid 38902449)
3. Shumway JT, Gambert SR (2002) Diabetic nephropathypathophysiology and management. Int Urol Nephrol 34:257-264. doi:10. 1023/A: 1023244829975
4. Schreuder MF, Delemarre-van de Waal H, Wijk AV (2006) Consequences of intrauterine growth restriction for the kidney. Kidney Blood Press Res 29:108-125. doi: 10.1159/000094538 (Pubitemid 44215216)
5. Schreuder MF, Nauta J (2007) Prenatal programming of nephron number and blood pressure. Kidney Int 72:265-268. doi:10. 1038/sj.ki. 5002307
6. Christensen T, Klebe JG, Bertelsen V et al (1989) Changes in renal volume during normal pregnancy. Acta Obstet Gynecol Scand 68:541. doi:10. 3109/00016348909015753
7. Davison JM, Hytten FE (1974) Glomerular filtration during and after pregnancy. J Obstet Gynaecol Br Commonw 81:588-595
8. Lindheimer MD, Katz AI (1981) The renal response to pregnancy. In: Brenner BM, Rector FC Jr (eds) The kidney. Saunders, Philadelphia, 1762-1815
9. Jeyabalan A, Lain KY (2007) Anatomic and functional changes of the upper urinary tract during pregnancy. Urol Clin North Am 34:1-6. doi:10. 1016/j.ucl. 2006.10.008
10. Conrad KP, Lindheimer MD (1999) Renal and cardiovascular alterations. In: Lindheimer MD, Roberts JM, Cunninngham FG (eds) Chesley's hypertensive disorders in pregnancy, 2nd edn. Appleton and Lange, Stamford, pp 263-326
11. Kalousek G, Hlavecek C, Nedoss B et al (1969) Circadian rhythms of creatinine and electrolyte excretion in healthy pregnant women. Am J Obstet Gynecol 103:856
12. Kincaid-Smith P (1975) The kidney: a clinico-pathological study. Blackwell, Oxford,222-239
13. Levey AS, Greene T, Beck GJ, Caggiula AW, Kusek JW, Hunsicker LG, Klahr S (1999) Dietary protein restriction and the progression of chronic renal disease: what have all of the results of the MDRD study shown? modification of diet in renal disease study group. J Am Soc Nephrol 10: 2426-2439
14. Baylis C, Rennke HG (1985) Renal hemodynamics and glomerular morphology in repetitively pregnant aging rats. Kidney Int 28:140-145. doi:10. 1038/ki. 1985.133
15. Hostetter TH, Rennke HG, Brenner BM (1982) The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies. Am J Med 72:375-380. doi:10. 1016/00029343(82) 90490-9
16. Tugtepe H, Sener G, Biyikli NK, Yuksel M, Cetinel S, Gedik N, Yegen BC (2007) The protective effect of oxytocin on renal ischemia/reperfusion injury in rats. Peptides 140:101-108. doi:10. 1016/j.regpep.2006.11.026
17. Biyikli NK, Tu?tepe H, Sener G, Velioǧlu-Oǧünç A, Cetinel S, Midillio?lu S, Gedik N, Ye?en BC (2006) Oxytocin alleviates oxidative renal injury in pyelonephritic rats via a neutrophil-dependent mechanism. Peptides 27: 2249-2257. doi:10. 1016/j.peptides. 2006.03.029
18. Nakazawa K, Makino T, Iizuka R, Kohsaka S, Tsukada Y (1984) Immunohistochemical study on oxytocin-like substance in the human placenta. Endocrinol Jpn 31:763-768
19. Liu JH, Rebar RW (2004) Endocrinology of pregnancy. Creasey RK, Resnik R, Iams JD (eds) Maternal-fetal medicine principles and practice, 5th edn. Saunders, Philadelphia, pp 121-134
20. Fuchs AR, Fuchs F, Husslein P, Soloff MS (1984) Oxytocin receptors in the human uterus during pregnancy and parturition. Am J Obstet Gynecol 150:734-741
21. Bird JE, Milhoan K, Wilson CB, Young SG, Mundy CA, Parthasarathy S, Blantz RC (1988) Ischemic acute renal failure and antioxidant therapy in the rat. The relation between glomerular and tubular dysfunction. J Clin Invest 81: 1630-1638. doi:10. 1172/JCI113498
22. Joosten SA, Sijpkens YW, van Kooten C, Paul LC (2005) Chronic renal allograft rejection: pathophysiologic considerations. Kidney Int 68:1-13. doi:10. 1111/j. 1523-1755. 2005.00376.x
23. Smith MC, Murdoch AP, Danielson LA, Conrad KP, Davison JM (2006) Relaxin has a role in establishing a renal response in pregnancy. Fertil Steril 86:253-255. doi: 10. 1016/j.fertnstert. 2005.11.070
24. Conrad KP, Novak J (2004) Emerging role of relaxin in renal and cardiovascular function. Am J Physiol Regul Integr Comp Physiol 287:250-261. doi:10. 1152/ajpregu. 00672.2003
25. Danielson LA, Sherwood OD, Conrad KP (1999) Relaxin is a potent renal vasodilator in conscious rats. J Clin Invest 103:525-533. doi:10. 1172/JCI5630
26. Palejwala S, Stein DE, Weiss G, Monia BP, Tortoriello D, Goldsmith LT (2001) Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway. Endocrinology 142:3405-3413. doi:10. 1210/en.142.8. 3405
27. Unemori EN, Amento EP (1990) Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts. J Biol Chem 265:10681-10685
28. Garber SL, Mirochnik Y, Brecklin CS, Unemori EN, Singh AK, Slobodskoy L, Grove BH, Arruda JA, Dunea G (2001) Relaxin decreases renal interstitial fibrosis and slows progression of renal disease. Kidney Int 59:876-882. doi: 10. 1046/j. 1523- 1755. 2001.059003876.x
29. Garber SL, Mirochnik Y, Brecklin C, Slobodskoy L, Arruda JA, Dunea G (2003) Effect of relaxin in two models of renal mass reduction. Am J Nephrol 23:8-12. doi: 10. 1159/000066302
30. Huang X, Cheng Z, Sunga J, Unemori E, Zsebo K (2001) Systemic administration of recombinant human relaxin (RHRLX) ameliorates the acute cyclosporine nephrotoxicity in rats. J Heart Lung Transplant 20:253. doi:10. 1016/S1053-2498(00)00577-5
31. McDonald GA, Sarkar P, Rennke H, Unemori E, Kalluri R, Suhatme VP (2003) Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo. Am J Physiol Renal Physiol 285:59-67