N-cadherin is depleted from proximal tubules in experimental and human acute kidney injury

Histochemistry and Cell Biology

Volumn 133, Issue 6, 2010, Pages 641-649

  Nurnberger J ^a   Feldkamp, F ^a   Kavapurackal, R ^a   Opazo Saez, A ^a   Becker, J ^b   Horbelt M ^a   Kribben, A ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Acute kidney injury; Adhesion junction; Cadherin; Ischemia

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA CATENIN; COLLAGEN TYPE 4; NERVE CELL ADHESION MOLECULE; UVOMORULIN;

ADULT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYPOXIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; NEPHRON; NONHUMAN; OPOSSUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL ARTERY; STAINING;

ANIMALS; CADHERINS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY FAILURE, ACUTE; KIDNEY TUBULES, PROXIMAL; MALE; OPOSSUMS; RATS; RATS, SPRAGUE-DAWLEY;

DIDELPHIDAE; RATTUS;

EID: 77954541852     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-010-0702-1     Document Type: Article

References (34)

1. Bush KT, Tsukamoto T, Nigam SK (2000) Selective degradation of E-cadherin and dissolution of E-cadherin-catenin complexes in epithelial ischemia. Am J Physiol Renal Physiol 278:F847-F852
2. Covington MD, Bayless KJ, Burghardt RC, Davis GE, Parrish AR (2005) Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases. Am J Physiol Renal Physiol 289:F280-F288
3. Engel U, Breborowicz D, Bog-Hansen T, Francis D (1997) Lectin staining of renal tubules in normal kidney. Apmis 105:31-34
4. Eschwege P, Paradis V, Conti M, Loric S, Dumas F, Berteau P, Ahmed M, Droupy S, Charpentier B, Legrand A, Bedossa P, Benoit G (1998) Bcl-2 and Bax expression on rat ischemic kidney. Transpl Proc 30:2861-2862
5. Feldkamp T, Kribben A, Roeser NF, Senter RA, Kemner S, Venkatachalam MA, Nissim I, Weinberg JM (2004) Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules. Am J Physiol Renal Physiol 286:F749-F759
6. Feldkamp T, Kribben A, Weinberg JM (2005) F1FO-ATPase activity and ATP dependence of mitochondrial energization in proximal tubules after hypoxia/reoxygenation. J Am Soc Nephrol 16:1742- 1751
7. Gopalakrishnan S, Dunn KW, Marrs JA (2002) Rac1, but not RhoA, signaling protects epithelial adherens junction assembly during ATP depletion. Am J Physiol Cell Physiol 283:C261-C272
8. Hagar H, Ueda N, Shah SV (1996) Role of reactive oxygen metabolites in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Am J Physiol 271:F209-F215
9. Hinck L, Nathke IS, Papkoff J, Nelson WJ (1994) Dynamics of cadherin/ catenin complex formation: novel protein interactions and pathways of complex assembly. J Cell Biol 125:1327-1340
10. Jiang J, Dean D, Burghardt RC, Parrish AR (2004) Disruption of cadherin/ catenin expression, localization, and interactions during HgCl2-induced nephrotoxicity. Toxicol Sci 80:170-182
11. Jung KY, Dean D, Jiang J, Gaylor S, Griffith WH, Burghardt RC, Parrish AR (2004) Loss of N-cadherin and alpha-catenin in the proximal tubules of aging male Fischer 344 rats. Mech Ageing Dev 125:445-453
12. Koch AW, Farooq A, Shan W, Zeng L, Colman DR, Zhou MM (2004) Structure of the neural (N-) cadherin prodomain reveals a cadherin extracellular domain-like fold without adhesive characteristics. Structure 12:793-805
13. Kovacs EM, Goodwin M, Ali RG, Paterson AD, Yap AS (2002) Cadherin- directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts. Curr Biol 12:379-382
14. Kribben A, Herget-Rosenthal S, Lange B, Michel MC, Philipp T (1998) Stimulation of mitogen activated protein kinase and cellular proliferation in renal proximal tubular cells. Ren Fail 20:229-234
15. Liano F, Pascual J (1996) Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group. Kidney Int 50:811-818
16. Mandel LJ, Doctor RB, Bacallao R (1994) ATP depletion: a novel method to study junctional properties in epithelial tissues. II. Internalization of Na+, K(+)-ATPase and E-cadherin. J Cell Sci 107(Pt 12):3315-3324
17. Molitoris BA (2004) Actin cytoskeleton in ischemic acute renal failure. Kidney Int 66:871-883
18. Molitoris BA, Marrs J (1999) The role of cell adhesion molecules in ischemic acute renal failure. Am J Med 106:583-592
19. Molitoris BA, Wilson PD, Schrier RW, Simon FR (1985) Ischemia induces partial loss of surface membrane polarity and accumulation of putative calcium ionophores. J Clin Invest 76:2097-2105
20. Moran SM, Myers BD (1985) Pathophysiology of protracted acute renal failure in man. J Clin Invest 76:1440-1448
21. Mori K, Lee HT, Rapoport D, Drexler IR, Foster K, Yang J, Schmidt-Ott KM, Chen X, Li JY, Weiss S, Mishra J, Cheema FH, Markowitz G, Suganami T, Sawai K, Mukoyama M, Kunis C, D'Agati V, Devarajan P, Barasch J (2005) Endocytic delivery of lipocalinsiderophore- iron complex rescues the kidney from ischemiareperfusion injury. J Clin Invest 115:610-621
22. Murata F, Tsuyama S, Suzuki S, Hamada H, Ozawa M, Muramatsu T (1983) Distribution of glycoconjugates in the kidney studied by use of labeled lectins. J Histochem Cytochem 31:139-144
23. Nouwen EJ, Dauwe S, van der Biest I, De Broe ME (1993) Stage- and segment-speciWc expression of cell-adhesion molecules N-CAM, A-CAM, and L-CAM in the kidney. Kidney Int 44:147-158 Nurnberger J, Bacallao RL, Phillips CL (2002) Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells. Mol Biol Cell 13:3096-3106
24. Nurnberger J, Bacallao RL, Phillips CL (2002) Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells. Mol Biol Cell 13:3096-3106
25. Nurnberger J, Kribben A, Opazo Saez A, Heusch G, Philipp T, Phillips CL (2004) The Invs gene encodes a microtubule-associated protein. J Am Soc Nephrol 15:1700-1710
26. Nurnberger J, Kavapurackal R, Zhang SJ, Saez AO, Heusch G, Philipp T, Pietruck F, Kribben A (2006) Differential tissue distribution of the Invs gene product inversin. Cell Tissue Res 323:147-155
27. Price VR, Reed CA, Lieberthal W, Schwartz JH (2002) ATP depletion of tubular cells causes dissociation of the zonula adherens and nuclear translocation of beta-catenin and LEF-1. J Am Soc Nephrol 13:1152-1161
28. Prozialeck WC, Lamar PC, Appelt DM (2004) Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron. BMC Physiol 4:10
29. Prozialeck WC, Edwards JR, Lamar PC, Smith CS (2006) Epithelial barrier characteristics and expression of cell adhesion molecules in proximal tubule-derived cell lines commonly used for in vitro toxicity studies. Toxicol In Vitro 20:942-953
30. Roitbak T, Ward CJ, Harris PC, Bacallao R, Ness SA, Wandinger-Ness A (2004) A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells. Mol Biol Cell 15:1334-1346
31. Saadi-Kheddouci S, Berrebi D, Romagnolo B, Cluzeaud F, Peuchmaur M, Kahn A, Vandewalle A, Perret C (2001) Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene. Oncogene 20:5972-5981
32. Takeichi M (1991) Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451-1455
33. Yap AS, Kovacs EM (2003) Direct cadherin-activated cell signaling: a view from the plasma membrane. J Cell Biol 160:11-16
34. Ympa YP, Sakr Y, Reinhart K, Vincent JL (2005) Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med 118:827-832