Effects of direct brain stimulation depend on seizure dynamics

Epilepsia

Volumn 51, Issue SUPPL. 3, 2010, Pages 93-97

  Jiruska, Premysl ^a   Powell, Andrew D ^a   Deans, Jacqueline K ^a   Jefferys, John G R ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

CA1; DC fields; Electrical stimulation; Epilepsy; Hippocampus; Interictal; Seizure

Indexed keywords

4 AMINOBUTYRIC ACID;

ALTERNATING CURRENT; BRAIN DEPTH STIMULATION; CLINICAL TRIAL; CONFERENCE PAPER; DIRECT CURRENT; DISEASE COURSE; ELECTROSTIMULATION; EPILEPSY; EPILEPTIC FOCUS; HUMAN; PRIORITY JOURNAL; SEIZURE; TREATMENT RESPONSE;

CA1 REGION, HIPPOCAMPAL; DEEP BRAIN STIMULATION; HIPPOCAMPUS; HUMANS; SEIZURES;

EID: 77954516774     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02619.x     Document Type: Conference Paper

References (20)

1. Bikson M, Lian J, Hahn PJ, Stacey WC, Sciortino C, Durand DM. (2001) Suppression of epileptiform activity by high frequency sinusoidal fields in rat hippocampal slices. J Physiol 531:181-191.
2. Bikson M, Hahn PJ, Fox JE, Jefferys JGR. (2003) Depolarization block of neurons during maintenance of electrographic seizures. J Neurophysiol 90:2402-2408.
3. Bikson M, Inoue M, Akiyama H, Deans JK, Fox JE, Miyakawa H, Jefferys JGR. (2004) Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. J Physiol 557:175-190.
4. Durand DM, Bikson M. (2001) Suppression and control of epileptiform activity by electrical stimulation: a review. Proc IEEE 89:1065-1082.
5. Gardner-Medwin AR, Nicholson C. (1983) Changes of extracellular potassium activity induced by electric current through brain tissue in the rat. J Physiol 335:375-392.
6. Gluckman BJ, Neel EJ, Netoff TI, Ditto WL, Spano ML, Schiff SJ. (1996) Electric field suppression of epileptiform activity in hippocampal slices. J Neurophysiol 76:4202-4205. (Pubitemid 27009721)
7. Heinemann U, Dietzel I. (1984) Extracellular potassium concentration in chronic alumina cream foci of cats. J Neurophysiol 52:421-434. (Pubitemid 14034160)
8. Jefferys JGR. (1979) Initiation and spread of action potentials in granule cells maintained in vitro in slices of guinea-pig hippocampus. J Physiol 289:375-388.
9. Jobst B. (2010) Brain stimulation for surgical epilepsy. Epilepsy Res 89:154-161.
10. Kohling R, Vreugdenhil M, Bracci E, Jefferys JGR. (2000) Ictal epileptiform activity is facilitated by hippocampal GABAA receptor-mediated oscillations. J Neurosci 20:6820-6829.
11. Lesser RP, Kim SH, Beyderman L, Miglioretti DL, Webber WR, Bare M, Cysyk B, Krauss G, Gordon B. (1999) Brief bursts of pulse stimulation terminate afterdischarges caused by cortical stimulation. Neurology 53:2073-2081.
12. Morrell M. (2006) Brain stimulation for epilepsy: Can scheduled or responsive neurostimulation stop seizures? Curr Opin Neurol 19:164-168.
13. Nakagawa M, Durand D. (1991) Suppression of spontaneous epileptiform activity with applied currents. Brain Res 567:241-247.
14. Oommen J, Morrell M, Fisher RS. (2005) Experimental Electrical Stimulation Therapy for Epilepsy. Curr Treat Options Neurol 7:261-271. (Pubitemid 41015270)
15. Schiller Y, Bankirer Y. (2007) Cellular mechanisms underlying antiepileptic effects of low- and high-frequency electrical stimulation in acute epilepsy in neocortical brain slices in vitro. J Neurophysiol 97:1887-1902. (Pubitemid 46411179)
16. Su Y, Radman T, Vaynshteyn J, Parra LC, Bikson M. (2008) Effects of high-frequency stimulation on epileptiform activity in vitro: ON/OFF control paradigm. Epilepsia 49:1586-1593.
17. Sun FT, Morrell MJ, Wharen RE Jr. (2008) Responsive cortical stimulation for the treatment of epilepsy. Neurotherapeutics 5:68-74.
18. Theodore WH, Fisher RS. (2004) Brain stimulation for epilepsy. Lancet Neurol 3:111-118.
19. Tranchina D, Nicholson C. (1986) A model for the polarization of neurons by extrinsically applied electric fields. Biophys J 50:1139-1156. (Pubitemid 17206000)
20. Traub RD, Colling SB, Jefferys JGR. (1995) Cellular mechanisms of 4-aminopyridine-induced synchronized after-discharges in the rat hippocampal slice. J Physiol 489(Pt 1):127-140.