A hybrid continuum-discrete modelling approach to predict and control angiogenesis: Analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

Volumn 368, Issue 1921, 2010, Pages 2937-2960

  Das, Anusuya ^a   Lauffenburger, Douglas ^a   Asada, Harry ^a   Kamm, Roger D ^a  

^a Massachusetts Institute of Technology   (United States)

Author keywords

Angiogenesis; Stochastic modelling; Three dimensional model

Indexed keywords

BIOMECHANICS; CELL DEATH; MORPHOLOGY; STOCHASTIC MODELS; STOCHASTIC SYSTEMS;

ANGIOGENESIS; ANGIOGENIC FACTOR; APOPTOSIS; BIOMECHANICAL FACTORS; BRANCHING PATTERNS; CELL CLUSTERING; CELL RESPONSE; CELL-CELL COMMUNICATIONS; CONTROLLED CONDITIONS; FIELD MODEL; GROWTH FACTOR; INDIVIDUAL CELLS; INFLUENCING FACTOR; INTEGRAL PART; MATRIX EFFECTS; MATRIX FIELDS; MODEL SIMULATION; PHYSIOLOGICAL PROCESS; STOCHASTIC MODELLING; THREE-DIMENSIONAL MODEL; TRANSITION PROBABILITIES;

THREE DIMENSIONAL;

SIGNAL PEPTIDE; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; BIOLOGICAL MODEL; BLOOD VESSEL; CELL COMMUNICATION; CYTOLOGY; ENDOTHELIUM CELL; HUMAN; METABOLISM; MICROFLUIDIC ANALYSIS; PHYSIOLOGY; REPRODUCIBILITY;

BLOOD VESSELS; CELL COMMUNICATION; ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PHYSIOLOGIC; REPRODUCIBILITY OF RESULTS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77954510806     PISSN: 1364503X     EISSN: None     Source Type: Journal    
DOI: 10.1098/rsta.2010.0085     Document Type: Article

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