Can we change the course of epilepsy in tuberous sclerosis complex?

Epilepsia

Volumn 51, Issue 7, 2010, Pages 1330-1331

  Curatolo, Paolo ^a   Moavero, Romina ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

VIGABATRIN;

COGNITION; DISEASE ASSOCIATION; DISEASE COURSE; EPILEPSY; FOLLOW UP; GENE MUTATION; HUMAN; LETTER; PRIORITY JOURNAL; RISK FACTOR; TUBEROUS SCLEROSIS;

EPILEPSY; HUMANS; TUBEROUS SCLEROSIS; VIGABATRIN;

EID: 77954502264     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02528.x     Document Type: Letter

References (11)

1. Bombardieri R, Pinci M, Moavero R, Cerminara C, Curatolo P. (2010) Early control of seizures improves long-term outcome in children with tuberous sclerosis complex. Eur J Paediatr Neurol 14:146-149.
2. Chu-Shore CJ, Major P, Camposano S, Muzykewicz D, Thiele EA. (2009) The natural history of epilepsy in tuberous sclerosis complex. Epilepsia 22 December 2009 [Epub ahead of print].
3. Curatolo P, Bombardieri R, Verdecchia M, Seri S. (2005) Intractable seizures in tuberous sclerosis complex: from molecular pathogenesis to the rationale for treatment. J Child Neurol 20:318-325. (Pubitemid 40766990)
4. Curatolo P, Bombardieri R, Jozwiak S. (2008) Tuberous sclerosis. Lancet 372:657-668.
5. Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, Silva AJ. (2008) Reversal of learning deficits in a Tsc2 +/) mouse model of tuberous sclerosis. Nat Med 14:843-848.
6. Holmes GL, Stafstrom CE. (2007) Tuberous sclerosis complex and epilepsy: recent developments and future challenges. Epilepsia 48:617-630.
7. Jansen FE, Vincken KL, Algra A, Anbeek P, Braams O, Nellist M, Zonnenberg BA, Jennekens-Schinkel A, van den Ouweland A, Halley D, van Huffelen AC, van Nieuwenhuizen O. (2008) Cognitive impairment in tuberous sclerosis complex is a multifactorial condition. Neurology 70:916-923.
8. Muncy J, Butler IJ, Koenig MK. (2009) Rapamycin reduces seizure frequency in tuberous sclerosis complex. J Child Neurol 24:477.
9. White R, Hua Y, Scheithauer B, Lynch DR, Henske EP, Crino PB. (2001) Selective alterations in glutamate and GABA receptor subunit mRNA expression in dysplastic neurons and giant cells of cortical tubers. Ann Neurol 49:67-78.
10. Winterkorn EB, Pulsifer MB, Thiele EA. (2007) Cognitive prognosis of patients with tuberous sclerosis complex. Neurology 68:62-64.
11. Zeng LH, Xu L, Gutmann DH, Wong M. (2008) Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol 63:444-453.