Respiratory involvement in inflammatory bowel diseases

Multidisciplinary Respiratory Medicine

Volumn 5, Issue 3, 2010, Pages 173-182

  D'Andrea, Nadia ^a   Vigliarolo, Rossana ^a   Sanguinetti, Claudio M ^a  

^a SAN FILIPPO NERI HOSPITAL   (Italy)

Author keywords

Crohn's disease; Inflammatory bowel disease; Respiratory involvement; Ulcerative colitis

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; METHACHOLINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 5; STEROID; TUMOR NECROSIS FACTOR ALPHA;

ASTHMA; BRONCHIOLITIS; BRONCHUS DISEASE; CLINICAL FEATURE; CROHN DISEASE; ENTERITIS; HUMAN; INCIDENCE; INTESTINE MUCOSA; LUNG FUNCTION TEST; LUNG PARENCHYMA; MORTALITY; PATHOGENESIS; RESPIRATORY TRACT DISEASE; REVIEW; ULCERATIVE COLITIS; CD4 CD8 RATIO; COUGHING; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DYSPNEA; FEVER; FORCED EXPIRATORY VOLUME; INFLAMMATORY BOWEL DISEASE; INNATE IMMUNITY; MALAISE; MOLECULAR PATHOLOGY; PROTEIN EXPRESSION; VITAL CAPACITY;

EID: 77954496817     PISSN: 1828695X     EISSN: 20496958     Source Type: Journal    
DOI: 10.1186/2049-6958-5-3-173     Document Type: Review

References (96)

1. Turner JR. Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application. Am J Pathol 2006;169:1901-1909.
2. Bamias G, Nyce M, De La Rue S, Cominelli F; American College of Physicians; American Physiological Society. New concepts in the pathophysiology of inflammatory bowel disease. Ann Intern Med 2005;143:895-904.
3. Lodes M, Cong Y, Elson CO, Mohamath R, Landers CJ, Targan SR, Fort M, Hershberg RM. Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest 2004;113:1296-1306. (Pubitemid 39069929)
4. Barnich N, Carvalho FA, Glasser AL, Darcha C, Jantscheff P, Allez M, Peeters H, Bommelaer G, Desreumaux P, Colombel JF, Darfeuille-Michaud A. CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest 2007;117:1566-1574.
5. Abraham C, Cho JH. Inflammatory bowel disease. N Engl J Med 2009;19:2066-2078.
6. Fuss IJ, Neurath M, Boirivant M, Klein JS, de la Motte C, Strong SA, Fiocchi C, Strober W. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of INF-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996;157:1261-1270.
7. Fujino S, Andoh A, Bamba S, Ogawa A, Hata K, Araki Y, Bamba T, Fujiyama Y. Increased expression of interleukin 17 in inflammatory bowel disease. Gut 2003;52:65-70. (Pubitemid 36020767)
8. Hugot JP, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, Naom I, Dupas JL, Van Gossum A, Orholm M, Bonaiti-Pellie C, Weissenbach J, Mathew CG, Lennard-Jones JE, Cortot A, Colombel JF, Thomas G. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996;379:821-823. (Pubitemid 26067722)
9. Cavanaugh J; IBD International Genetics Consortium. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16. Am J Hum Genet 2001;68:1165-1171.
10. Abraham C, Cho JH. Functional consequences of NOD2 (CARD15) mutations. Inflamm Bowel Dis 2006;12:641-650. (Pubitemid 43977746)
11. Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nuñez G, Flavell RA. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005;307:731-734.
12. Lesage S, Zouali H, Cézard JP, Colombel JF, Belaiche J, Almer S, Tysk C, O'Morain C, Gassull M, Binder V, Finkel Y, Modigliani R, Gower-Rousseau C, Macry J, Merlin F, Chamaillard M, Jannot AS, Thomas G, Hugot JP; EPWG-IBD Group; EPIMAD Group; GETAID Group. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 2002;70:845-857.
13. Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol 2004;99:2393-2404.
14. Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Günther S, Prescott NJ, Onnie CM, Häsler R, Sipos B, Fölsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007;39:207-211. (Pubitemid 46184351)
15. Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008;456:259-263.
16. Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 2007;7:767-777. (Pubitemid 47480305)
17. Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 2008;455:396-400.
18. Kraft SC, Earle RH, Roesler M, Esterly JR. Unexplained bronchopulmonary disease with inflammatory bowel disease. Arch Intern Med 1976;136:454-459.
19. Storch I, Sachar D, Katz S. Pulmonary manifestations of inflammatory bowel disease. Inflamm Bowel Dis 2003;9:104-115. (Pubitemid 36367319)
20. Greenstein AJ, Janowitz HD, Sachar DB. The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine 1976;55:401-412.
21. Veloso FT, Carvalho J, Magro F. Immune-related manifestations of inflammatory bowel disease. A prospective study of 792 patients. J Clin Gastroenterol 1996;23:29-34.
22. Edwards FC, Truelove SC. The course and prognosis of ulcerative colitis. III. Complications. Gut 1964;5:1-22.
23. Rogers BH, Clark LM, Kirsner JB. The epidemiologic and demographic characteristics of inflammatory bowel disease: an analysis of a computerized file of 1400 patients. J Chronic Dis 1971; 24:743-773.
24. Raj AA, Birring SS, Green R, Grant A, de Caestecker J, Pavord ID. Prevalence of inflammatory bowel disease in patients with airways disease. Respir Med 2008;102:780-785.
25. Camus P, Colby TV. The lung in inflammatory bowel disease. Eur Respir J 2000;15:5-10.
26. Mohamed-Hussein AA, Mohamed NA, Ibrahim ME. Changes in pulmonary function in patients with ulcerative colitis. Respir Med 2007;101:977-982.
27. Munck A, Murciano D, Pariente R, Cezard JP, Navarro J. Latent pulmonary function abnormalities in children with Crohn's disease. Eur Respir J 1995;8:377-380.
28. Tzanakis N, Bouros D, Samiou M, Panagou P, Mouzas J, Manousos O, Siafakas N. Lung function in patients with inflammatory bowel disease. Respir Med 1998;92:516-522. (Pubitemid 28162164)
29. Herrlinger KR, Noftz MK, Dalhoff K, Ludwig D, Stange EF, Fellermann K. Alterations in pulmonary function in inflammatory bowel disease are frequent and persist during remission. Am J Gastroenterol 2002;97:377-381.
30. Douglas JG, McDonald CF, Leslie MJ, Gillon J, Crompton GK, McHardy GJ. Respiratory impairment in inflammatory bowel disease: does it vary with disease activity? Respir Med 1989;83:389-394.
31. Bonniere P, Wallaert B, Cortot A, Marchandise X, Riou Y, Tonnel AB, Colombel JF, Voisin C, Paris JC. Latent pulmonary involvement in Crohn's disease: biological, functional, bronchoalveolar lavage and scintigraphic studies. Gut 1986;27:919-925. (Pubitemid 16044263)
32. Dierkes-Globisch A, Mohr H. Pulmonary function abnormalities in respiratory asymptomatic patients with inflammatory bowel disease. Eur J Intern Med 2002;13:385.
33. Wallaert B, Colombel JF, Tonnel AB, Bonniere P, Cortot A, Paris JC, Voisin C. Evidence of lymphocyte alveolitis in Crohn's disease. Chest 1985;87:363-367. (Pubitemid 15139967)
34. Sarioǧlu N, Türkel N, Sakar A, Celik P, Saruç M, Demir MA, Göktan C, Kirmaz C, Yüceyar H, Yorgancioǧlu A. Lung involvement in inflammatory bowel diseases. Ann Saudi Med 2006;26:407-408.
35. Camus P, Piard F, Ashcroft T, Gal AA, Colby TV. The lung in inflammatory bowel disease. Medicine 1993;72:151-183.
36. Black H, Mendoza M, Murin S. Thoracic manifestations of inflammatory bowel disease. Chest 2007;131:524-532.
37. Fishman AP, Fishman JA, Grippi MA, Elias JA, Senior RM, Pack AI. In: Fishman AP, ed. Fishman's pulmonary diseases and disorders. New York: McGraw Hill, 1998:838.
38. Spira A, Grossman R, Balter M. Large airway disease associated with inflammatory bowel disease. Chest 1998;113:1723-1726. (Pubitemid 28307187)
39. Kelly MG, Frizelle FA, Thornley PT, Beckert L, Epton M, Lynch AC. Inflammatory bowel disease and the lung: is there a link between surgery and bronchiectasis? Int J Colorectal Dis 2006;21:754-757.
40. Songür N, Songür Y, Tüzün M, Doǧan I, Tüzün D, Ensari A, Hekimoglu B. Pulmonary function tests and high-resolution CT in the detection of pulmonary involvement in inflammatory bowel disease. J Clin Gastoenterol 2003;37:292-298.
41. Tzanakis N, Samiou M, Bouros D, Mouzas J, Kouroumalis E, Siafakas NM. Small airways function in patients with inflammatory bowel disease. Am J Respir Crit Care Med 1998;157:382-386. (Pubitemid 28090524)
42. Kraft SC, Earle RH, Roesler M, Esterly JR. Unexplained bronchopulmonary disease with inflammatory bowel disease. Arch Intern Med 1976;136:454-459.
43. Vandenplas O, Casel S, Delos M, Trigaux JP, Melange M, Marchand E. Granulomatous bronchiolitis associated with Crohn's disease. Am J Respir Crit Care Med 1998;158:1676-1679.
44. Desai SJ, Gephardt GN, Stoller JK. Diffuse panbronchiolitis preceding ulcerative colitis. Chest 1989;95:1342-1344.
45. Hilling GA, Robertson DA, Chalmers AH, Rigby HS. Unusual pulmonary complication of ulcerative colitis with a rapid response to corticosteroids: case report. Gut 1994;35:847-848.
46. Ward H, Fisher KL, Waghray R, Wright JL, Card SE, Cockcroft DW. Constrictive bronchiolitis and ulcerative colitis. Can Respir J 1999;6:197-200.
47. Trow TK, Morris DG, Miller CR, Homer RJ. Granulomatous bronchiolitis of Crohn's disease successfully treated with inhaled budesonide. Thorax 2009;64:546-547.
48. Bentur L, Lachter J, Koren I, Ben-Izhak O, Lavy A, Bentur Y, Rosenthal E. Severe pulmonary disease in association with Crohn's disease in a 13-year-old girl. Pediatr Pulmonol 2000;29:151-154.
49. Bernstein CN, Blanchard JF, Rawsthorne P, Yu N. The prevalence of extraintestinal diseases in inflammatory bowel disease: a population-based study. Am J Gastroenterol 2001;96:1116-1122.
50. Louis E, Louis R, Drion V, Bonnet V, Lamproye A, Radermecker M, Belaiche J. Increased frequency of bronchial hyperresponsiveness in patients with inflammatory bowel disease. Allergy 1995;50:729-733.
51. Troncone R, Merrett TG, Ferguson A. Prevalence of atopy is unrelated to presence of inflammatory bowel disease. Clin Allergy 1988;18:111-117.
52. Levo Y, Shalit M, Wollner S, Fich A. Serum IgE levels in patients with inflammatory bowel disease. Ann Allergy 1986;56:85-87. (Pubitemid 16155591)
53. Mansi A, Cucchiara S, Greco L, Sarnelli P, Pisanti C, Franco MT, Santamaria F. Bronchial hyperresponsiveness in children and adolescents with Crohn's disease. Am J Respir Crit Care Med 2000;161:1051-1054. (Pubitemid 30171771)
54. Clifford RD, Radford M, Howell JB, Holgate ST. Prevalence of respiratory symptoms among 7 and 11 year old school-children and association with asthma. Arch Dis Child 1989;64:1118-1125. (Pubitemid 19208714)
55. Ceyhan BB, Karakurt S, Cevik H, Sungur M. Bronchial hyperreactivity and allergic status in inflammatory bowel disease. Respiration 2003;70:60-66.
56. Bartholo RM, Zaltman C, Elia C, Cardoso AP, Flores V, Lago P, Cassabian L, Dorileo FC, Lapa-e-Silva JR. Bronchial hyperresponsiveness and analysis of induced sputum cells in Crohn's disease. Braz J Med Biol Res 2005;38:197-203.
57. Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 2003;3:521-533.
58. Main J, McKenzie H, Yeaman GR, Kerr MA, Robson D, Pennington CR, Parratt D. Antibody to Saccharomyces cerevisiae (bakers' yeast) in Crohn's disease. BMJ 1988;297:1105-1106.
59. Birring SS, Birghtling CE, Symon FA, Barlow SG, Wardlaw AJ, Pavord ID. Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis. Thorax 2003;58:1066-1070.
60. Kinnear W, Higenbottam T. Pulmonary manifestations of inflammatory bowel disease. Intern Med Spec 1983;4:104-111.
61. Adenis A, Colombel JF, Lecouffe P, Wallaert B, Hecquet B, Marchandise X, Cortot A. Increased pulmonary and intestinal permeability in Crohn's disease. Gut 1992;33:678-682.
62. Gursoy S, Guven K, Kula M, Canoz O, Yurci A, Unluhizarci K, Ozbakir O, Yucesoy M. Subclinical alveolar involvement in ulcerative colitis. Inflamm Bowel Dis 2005;11:372-375.
63. Ludwig D, Stange EF. Treatment of ulcerative colitis. Hepatogastroenterology 2000;47:83-89.
64. Ford RM. Transient pulmonary eosinophilia and asthma. A review of 20 cases occurring in 5,702 asthma sufferers. Am Rev Respir Dis 1966;93:797-803.
65. Tanigawa K, Sugiyama K, Matsuyama H, Nakao H, Kohno K, Komuro Y, Iwanaga Y, Eguchi K, Kitaichi M, Takagi H. Mesalazine-induced eosinophilic pneumonia. Respiration 1999;66:69-72.
66. Heffner JE, Sahn S. Salycilate-induced pulmonary edema. Clinical features and prognosis. Ann Intern Med 1981;95:405-409.
67. Serghini M, Karoui S, Meknini M, Matri S, Kallel L, Fekih M, Boubaker J, Filali A. Treatment of Crohn's disease by infliximab. About 20 cases. Tunis Med 2009;87:579-582.
68. Takasaka N, Toyota E, Shimada M, Ariga H, Teramoto S, Akagawa S. Two cases of tuberculosis after treatment of rheumatoid arthritis with infliximab. Nihon Kokyuki Gakkai Zasshi 2010;48:60-65.
69. Dixon WG, Hyrich KL, Watson KD, Lunt M, Galloway J, Ustianowski A; B S R B R Control Centre Consortium, Symmons DP; BSR Biologics Register. Drug-specific risk of tuberculosis in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register (BSRBR). Ann Rheum Dis 2010;69:522-528.
70. Kuźniar T, Sieiman C, Brugière O, Groussard O, Mal H, Mellot F, Pariente R, Malolepszy J, Fournier M. Severe tracheobronchial stenosis in a patient with Crohn's disease. Eur Respir J 2000;15:209-212.
71. Eaton TE, Lambie N, Wells AJ. Bronchiectasis following colectomy for Crohn's disease. Thorax 1998;53:529-531. (Pubitemid 28308074)
72. Higenbottam T, Cochrane GM, Clark TJ, Turner D, Millis R, Seymour W. Bronchial disease in ulcerative colitis. Thorax 1980;35:581-585.
73. Mahadeva R, Walsh G, Flower CD, Shneerson JM. Clinical and radiological characteristics of lung disease in inflammatory bowel disease. Eur Respir J 2000;15:41-48.
74. Bernstein CN, Wajda A, Blanchard JF. The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study. Gastroenterology 2005;129:827-836.
75. Mahajan L, Kay M, Wyllie R, Steffen R, Goldfarb J. Ulcerative colitis presenting with bronchiolitis obliterans organizing pneumonia in a pediatric patient. Am J Gastroenterol 1997;92:2123-2124.
76. Swinburn CR, Jackson GJ, Cobden I, Ashcroft T, Morritt GN, Corris PA. Bronchiolitis obliterans organising pneumonia in a patients with ulcerative colitis. Thorax 1988;43:735-736.
77. Gil-Simón P, Barrio Andrés J, Atienza Sánchez R, Julián Gómez L, López Represa C, Caro-Patón A. Bronchiolitis obliterans organizing pneumonia and Crohn's disease. Rev Esp Enferm Dig 2008;100:175-177.
78. Carratù P, Dragonieri S, Nocerino MC, Trabucco SM, Lacedonia D, Parisi G, Resta O. A case of cryptogenic organizing pneumonia occurring in Crohn's disease. Can Respir J 2005;12:437-439.
79. Faller M, Gasser B, Massard G, Pauli G, Quoix E. Pulmonary migratory infiltrates and pachypleuritis in a patient with Crohn's disease. Respiration 2000;67:459-463. (Pubitemid 30666014)
80. Parry SD, Barbatzas C, Peel ET, Barton JR. Sulfasalazine and lung toxicity. Eur Respir J 2002;19:756-764.
81. Averbuch M, Halpern Z, Hallak A, Topilsky M, Levo Y. Sulfasalazine pneumonitis. Am J Gastroenterol 1985;80:343-345.
82. Margagnoni G, Papi V, Aratari A, Triolo L, Papi C. Methotrexate-induced pneumonitis in a patients with Crohn's disease. Journal of Crohn's and Colitis 2010;4:211-214.
83. Brechmann T, Heyer C, Schmiegel W. Methotrexate-induced pneumonitis in a woman with Crohn's disease. Dtsch Med Wochenschr 2007;132:1759-1762.
84. Keane J, Gershon S, Wise RP, Mirabile-Levens E, Kasznica J, Schwieterman WD, Siegel JN, Braun MM. Tuberculosis associated with infliximab, a tumor necrosis factor alphaneutralizing agent. N Engl J Med 2001;345:1098-1104.
85. Jess T, Gamborg M, Munkholm P, Sørensen TI. Overall and cause-specific mortality in ulcerative colitis: meta-analysis of population-based inception cohort studies. Am J Gastroenterol 2007;102:609-617.
86. Cucino C, Sonnenberg A. Cause of death in patients with inflammatory bowel disease. Inflamm Bowel Dis 2001;7:250-255. (Pubitemid 32776519)
87. Höie O, Schouten LJ, Wolters FL, Solberg IC, Riis L, Mouzas IA, Politi P, Odes S, Langholz E, Vatn M, Stockbrügger RW, Moum B; European Collaborative Study Group of Inflammatory Bowel Disease (EC-IBD). Ulcerative colitis: no rise in mortality in a European-wide population based cohort 10 years after diagnosis. Gut 2007;56:497-503.
88. Jacobsen B, Puho E, Fallingborg J, et al. Mortality in ulcerative colitis in the North Jutland County. A population based 26 years follow-up study. (Abstr). Gut 2005;54:A6.
89. Duricova D, Pedersen N, Elkjaer M, Gamborg M, Munkholm P, Jess T. Overall and cause-specific mortality in Crohn's disease: a meta-analysis of population-based studies. Inflamm Bowel Dis 2010;16:347-353.
90. Birrenbach T, Böcker U. Inflammatory bowel disease and smoking: a review of epidemiology, pathophysiology, and therapeutic implications. Inflamm Bowel Dis 2004;10:848-859.
91. Canavan C, Abrams K, Mayberry JF. Meta-analysis: mortality in Crohn's disease. Aliment Pharmacol Ther 2007;25:861-870.
92. Karadag F, Ozhan MH, Akçiçek E, Günel O, Alper H, Veral A. Is it possible to detect ulcerative colitis-related respiratory syndrome early? Respirology 2001;6:341-346.
93. Gevenois PA, De Vuyst P, Sy M, Scillia P, Chaminade L, de Maertelaer V, Zanen J, Yernault JC. Pulmonary emphysema: quantitative CT during expiration. Radiology 1996;199:825-829.
94. Newman KB, Lynch DA, Newman LS, Ellegood D, Newell JD Jr. Quantitative computed tomography detects air trapping due to asthma. Chest 1994;106:105-109. (Pubitemid 24214737)
95. Hansell DM, Wells AU, Padley SP, Müller NL. Hypersensitivity pneumonitis: correlation of individual CT patterns with functional abnormalities. Radiology 1996;199:123-128.
96. Kuzela L, Vavrecka A, Prikazska M, Drugda B, Hronec J, Senkova A, Drugdova M, Oltman M, Novotna T, Brezina M, Kratky A, Kristufek P. Pulmonary complications in patients with inflammatory bowel disease. Hepatogastroenterology 1999;46:1714-1719. (Pubitemid 29366330)