The Fps1p aquaglyceroporin facilitates the use of small aliphatic amides as a nitrogen source by amidase-expressing yeasts

FEMS Yeast Research

Volumn 10, Issue 5, 2010, Pages 527-534

  Shepherd, Andrew ^a   Piper, Peter W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

amidase; aquaglyceroporin; food spoilage; Fps1p; Saccharomyces cerevisiae; Zygosaccharomyces rouxii

Indexed keywords

ACETAMIDE; ACETIC ACID; ACROLEIN; ALLYL ALCOHOL; AMIDASE; AMIDE; AQUAGLYCEROPORIN; NITROGEN; PROTEIN FPS1P; PROTEIN ZRAMD1; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; PROPANOL;

AMINO ACID SEQUENCE; ARTICLE; ASPERGILLUS NIDULANS; DIFFUSION; HETEROLOGOUS EXPRESSION; NONHUMAN; OPEN READING FRAME; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; ZYGOSACCHAROMYCES ROUXII; DRUG EFFECTS; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; TOXICITY; ZYGOSACCHAROMYCES;

ACETIC ACID; ACROLEIN; AMIDES; AMIDOHYDROLASES; ANTIFUNGAL AGENTS; AQUAGLYCEROPORINS; GENE DELETION; NITROGEN; PROPANOLS; SACCHAROMYCES CEREVISIAE; ZYGOSACCHAROMYCES;

EID: 77954496148     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2010.00636.x     Document Type: Article

References (27)

1. Agre P Kozono D (2003) Aquaporin water channels: molecular mechanisms for human diseases. FEBS Lett 555 : 72 78.
2. Casal M, Cardoso H Leao C (1996) Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae. Microbiology 142 : 1385 1390.
3. De Boer L (2009) Novel process for enzymatic acrylamide reduction in food products. US patent 2009/0098248.
4. Harris JC, Plummer S, Turner MP Lloyd D (2000) The microaerophilic flagellate Giardia intestinalis: Allium sativum (garlic) is an effective antigiardial. Microbiology 146 : 3119 3127.
5. Hohmann S, Krantz M Nordlander B (2007) Yeast osmoregulation. Method Enzymol 428 : 29 45.
6. Jansen M, Veurink JH, Euverink GJ Dijkhuizen L (2003) Growth of the salt-tolerant yeast Zygosaccharomyces rouxii in microtiter plates: effects of NaCl, pH and temperature on growth and fusel alcohol production from branched-chain amino acids. FEMS Yeast Res 3 : 313 318.
7. Karlgren S, Pettersson N, Nordlander B et al 2005) Conditional osmotic stress in yeast: a system to study transport through aquaglyceroporins and osmostress signaling. J Biol Chem 280 : 7186 7193.
8. King LS, Kozono D Agre P (2004) From structure to disease: the evolving tale of aquaporin biology. Nat Rev Mol Cell Bio 5 : 687 698.
9. Kirk N Piper PW (1994) Growth rate influences MF alpha 1 promoter activity in MAT alpha Saccharomyces cerevisiae. Appl Microbiol Biot 42 : 340 345.
10. Ling M, Merante F Robinson BH (1995) A rapid and reliable DNA preparation method for screening a large number of yeast clones by polymerase chain reaction. Nucleic Acids Res 23 : 4924 4925.
11. Marzluf GA (1997) Genetic regulation of nitrogen metabolism in the fungi. Microbiol Mol Biol R 61 : 17 32.
12. Mollapour M Piper PW (2007) Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid. Mol Cell Biol 27 : 6446 6556.
13. Paiva S, Devaux F, Barbosa S, Jacq C Casal M (2004) Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae. Yeast 21 : 201 210.
14. Panaretou B, Sinclair K, Prodromou C, Johal J, Pearl L Piper PW (1999) The Hsp90 of Candida albicans can confer Hsp90 functions in Saccharomyces cerevisiae: a potential model for the processes that generate immunogenic fragments of this molecular chaperone in C. albicans infections. Microbiology 145 : 3455 3463. (Pubitemid 30018789)
15. Pribylova L, de Montigny J Sychrova H (2007) Osmoresistant yeast Zygosaccharomyces rouxii: the two most studied wild-type strains (ATCC 2623 and ATCC 42981) differ in osmotolerance and glycerol metabolism. Yeast 24 : 171 180.
16. Read JD, Colussi PA, Ganatra MB Taron CH (2007) Acetamide selection of Kluyveromyces lactis cells transformed with an integrative vector leads to high-frequency formation of multicopy strains. Appl Environ Microb 73 : 5088 5096.
17. Sousa MJ, Rodrigues F, CorteReal M Leao C (1998) Mechanisms underlying the transport and intracellular metabolism of acetic acid in the presence of glucose in the yeast Zygosaccharomyces bailii. Microbiology 144 : 665 670.
18. Tang XM, Kayingo G Prior BA (2005) Functional analysis of the Zygosaccharomyces rouxii Fps1p homologue. Yeast 22 : 571 581.
19. Tareke E, Rydberg P, Karlsson P, Eriksson S Tornqvist M (2000) Acrylamide: a cooking carcinogen? Chem Res Toxicol 13 : 517 522.
20. Teixeira MC, Raposo LR, Mira NP, Lourenco AB Sa-Correia I (2009) Genome-wide identification of genes required for maximal tolerance to ethanol in yeast: important role of FPS1. Appl Environ Microb 75 : 5761 5762.
21. Thorsen M, Di Y, Tangemo C et al 2006) The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast. Mol Biol Cell 17 : 4400 4410.
22. Toh TH, Kayingo G, van der Merwe MJ, Kilian SG, Hallsworth JE, Hohmann S Prior BA (2001) Implications of FPS1 deletion and membrane ergosterol content for glycerol efflux from Saccharomyces cerevisiae. FEMS Yeast Res 1 : 205 211.
23. Trotter EW, Collinson EJ, Dawes IW Grant CM (2006) Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae. Appl Environ Microb 72 : 4885 4892.
24. Uchida K, Kanematsu M, Morimitsu Y, Osawa T, Noguchi N Niki E (1998) Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J Biol Chem 273 : 16058 16066.
25. Wach A, Brachat A, Poehlmann R Philippsen P (1994) New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10 : 1793 1808.
26. Wysocki R, Chery CC, Wawrzycka D, Van Hulle M, Cornelis R, Thevelein JM Tamas MJ (2001) The glycerol channel Fps1p mediates the uptake of arsenite and antimonite in Saccharomyces cerevisiae. Mol Microbiol 40 : 1391 1401.
27. Zeuthen T, Wu B, Pavlovic-Djuranovic S et al 2006) Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypanosoma brucei. Mol Microbiol 61 : 1598 1608.