Biomarker-based risk stratification for previously untreated medullary thyroid cancer

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 6, 2010, Pages 2655-2663

  Machens, Andreas ^a   Dralle, Henning ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CARCINOEMBRYONIC ANTIGEN; PENTAGASTRIN; TUMOR MARKER;

ARTICLE; CALCITONIN BLOOD LEVEL; CANCER RISK; CANCER STAGING; CANCER SURGERY; CERVICAL LYMPH NODE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DISTANT METASTASIS; FEMALE; FISTULA; HISTOPATHOLOGY; HORNER SYNDROME; HUMAN; HYPOPARATHYROIDISM; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM LYMPH NODE; MORBIDITY; NECK DISSECTION; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RECURRENT LARYNGEAL NERVE PALSY; REOPERATION; RETROSPECTIVE STUDY; RISK ASSESSMENT; SURGICAL INFECTION; THYROID MEDULLARY CARCINOMA; THYROIDECTOMY; TUMOR VOLUME; BLOOD; COHORT ANALYSIS; LYMPH NODE; MEDULLARY CARCINOMA; PATHOLOGY; STATISTICAL ANALYSIS; THYROID TUMOR;

CALCITONIN; CARCINOEMBRYONIC ANTIGEN; CARCINOMA, MEDULLARY; COHORT STUDIES; DATA INTERPRETATION, STATISTICAL; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; NEOPLASM STAGING; POSTOPERATIVE COMPLICATIONS; REOPERATION; RETROSPECTIVE STUDIES; RISK ASSESSMENT; THYROID NEOPLASMS; THYROIDECTOMY; TUMOR MARKERS, BIOLOGICAL;

EID: 77954464365     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-2368     Document Type: Article

References (32)

1. Kouvaraki MA, Shapiro SE, Fornage BD, Edeiken-Monro BS, Sherman SI, Vassilopoulou-Sellin R, Lee JE, Evans DB 2003 Role of preoperative ultrasonography in the surgical management of patients with thyroid cancer. Surgery 134:946-955 (Pubitemid 38010740)
2. Osamura RY, Yasuda O, Kawakami T, Itoh Y, Inada K, Kakudo K 1997 Immunoelectron microscopic demonstration of regulated pathway for calcitonin and constitutive pathway for carcinoembryonic antigen in the same cells of human medullary carcinomas of thyroid glands. Mod Pathol 10:7-11 (Pubitemid 27090769)
3. Wells Jr SA, Haagensen DE, Linehan WM, Farrell RE, Dilley WG 1978 The detection of elevated plasma levels of carcinoembryonic antigen in patients with suspected or established medullary thyroid carcinoma. Cancer 42(Suppl 3):S1498-S1503
4. Cohen R, Campos JM, Salaün C, Heshmati HM, Kraimps JL, Proye C, Sarfati E, Henry JF, Niccoli-Sire P, Modigliani E 2000 Preoperative calcitonin levels are predictive of tumor size and postoperative calcitonin normalization in medullary thyroid carcinoma. Groupe d'Etudes des Tumeurs à Calcitonine (GETC). J Clin Endocrinol Metab 85:919-922
5. Machens A, Schneyer U, Holzhausen HJ, Dralle H 2005 Prospects of remission in medullary thyroid carcinoma according to basal calcitonin level. J Clin Endocrinol Metab 90:2029-2034
6. Machens A, Ukkat J, Hauptmann S, Dralle H 2007 Abnormal carcinoembryonic antigen levels and medullary thyroid cancer progression. A multivariate analysis. Arch Surg 142:289 -293; discussion 294
7. Barbet J, Campion L, Kraeber-Bodéré F, Chatal JF; GTE Study Group 2005 Prognostic impact of serum calcitonin and carcinoembryonic antigen doubling-times in patients with medullary thyroid carcinoma. J Clin Endocrinol Metab 90:6077-6084
8. Chatal JF, Campion L, Kraeber-Bodéré F, Bardet S, Vuillez JP, Charbonnel B, Rohmer V, Chang CH, Sharkey RM, Goldenberg DM,Barbet J 2006 Surgical improvement in patients with medullary thyroid carcinoma who undergo pretargeted anti-carcinoembryonic-antigen radioimmunotherapy: a collaborative study with the French Endocrine Tumor Group. J Clin Oncol 24:1705-1711
9. Laure Giraudet A, Al Ghulzan A, Aupérin A, Leboulleux S, Chehboun A, Troalen F, Dromain C, Lumbroso J, Baudin E, Schlumberger M 2008 Progression of medullary thyroid carcinoma: assessment with calcitonin and carcinoembryonic antigen doubling times. Eur J Endocrinol 158:239-246
10. Karges W, Dralle H, Raue F, Mann K, Reiners C, Grussendorf M, Hüfner M, Niederle B, Brabant G, German Society for Endocrinology (DGE)-Thyroid Section 2004 Calcitonin measurement to detect medullary thyroid carcinoma in nodular goiter: German evidence-based consensus recommendations. Exp Clin Endocrinol Diabetes 112:52-58
11. Elisei R, Bottici V, Luchetti F, Di Coscio G, Romei C, Grasso L, Miccoli P, Iacconi P, Basolo F, Pinchera A, Pacini F 2004 Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders. J Clin Endocrinol Metab 89:163-168 (Pubitemid 38183876)
12. Costante G, Meringolo D, Durante C, Bianchi D, Nocera M, Tumino S, Crocetti U, Attard M, Maranghi M, Torlontano M, Filetti S 2007 Predictive value of serum calcitonin levels for preoperative diagnosis of medullary thyroid carcinoma in a cohort of 5817 consecutive patients with thyroid nodules. J Clin Endocrinol Metab 92:450-455
13. Scheuba C, Kaserer K, Moritz A, Drosten R, Vierhapper H, Bieglmayer C, Haas OA, Niederle B 2009 Sporadic hypercalcitoninemia. Clinical and therapeutic consequences. Endocr Relat Cancer 16:243-253
14. Rink T, Truong PN, Schroth HJ, Diener J, Zimny M, Grünwald F 2009 Calculation and validation of a plasma calcitonin limit for early detection of medullary thyroid carcinoma in nodular thyroid disease. Thyroid 19:327-332
15. Machens A, Hoffmann F, Sekulla C, Dralle H 2009 Importance of gender-specific calcitonin thresholds in screening for occult sporadic medullary thyroid cancer. Endocr Relat Cancer 16:1291-1298
16. Machens A, Lorenz K, Dralle H 2009 Individualization of lymph node dissection in RET (rearranged during transfection) carriers at risk for medullary thyroid cancer: value of pretherapeutic calcitonin levels. Ann Surg 250:305-310
17. Machens A, Hauptmann S, Dralle H 2008 Medullary thyroid cancer responsiveness to pentagastrin stimulation: an early surrogate parameter of tumor dissemination? J Clin Endocrinol Metab 93:2234-2238
18. Bieglmayer C, Vierhapper H, Dudczak R, Niederle B 2007 Measurement of calcitonin by immunoassay analyzers. Wien Klin Wochenschr 45:662-666
19. Bieglmayer C, Scheuba C, Niederle B, Flores J, Vierhapper H 2002 Screening for medullary thyroid carcinoma: experience with different immunoassays for human calcitonin. Wien Klin Wochenschr 114:267-273 (Pubitemid 34450419)
20. Dralle H, Damm I, Scheumann GF, Kotzerke J, Kupsch E, Geerlings H, Pichlmayr R 1994 Compartment-oriented microdissection of regional lymph nodes in medullary thyroid carcinoma. Surg Today 24:112-121 (Pubitemid 24081294)
21. Dralle H 2002 Lymph node dissection and medullary thyroid carcinoma. Br J Surg 89:1073-1075
22. Röher HD, Simon D, Goretzki PE 1997 Guidelines in oncologic surgery: malignant thyroid tumors. Langenbecks Arch Chir 114 (Suppl 2):S142
23. Hinze R, Holzhausen HJ, Gimm O, Dralle H, Rath FW 1998 Primary hereditary medullary thyroid carcinoma-C-cell morphology and correlation with preoperative calcitonin levels. Virchows Arch 433:203-208
24. Machens A, Hauptmann S, Dralle H 2008 Referral bias in thyroid cancer surgery: directionandmagnitude. Eur J Surg Oncol 34:556-562
25. Machens A, Holzhausen HJ, Dralle H 2004 Prediction of mediastinal lymph node metastasis in medullary thyroid carcinoma. Br J Surg 91:709-712
26. Fleming JB, Lee JE, Bouvet M, Schultz PN, Sherman SI, Sellin RV, Friend KE, Burgess MA, Cote GJ, Gagel RF, Evans DB 1999 Surgical strategy for the treatment of medullary thyroid carcinoma. Ann Surg 230:697-707
27. Moley JF, DeBenedetti MK 1999 Patterns of nodal metastases in palpable medullary thyroid carcinoma. Recommendations for extent of node dissection. Ann Surg 229:880-888
28. Ball DW 2009 American Thyroid Association guidelines for management of medullary thyroid cancer: an adult endocrinology perspective. Thyroid 6:547-550
29. Machens A, Hinze R, Lautenschläger C, Thomusch O, Dralle H 2001 Thyroid carcinoma invading the cervicovisceral axis: routes of invasion and clinical implications. Surgery 129:23-28
30. Porterfield JR, Factor DA, Grant CS 2009 Operative technique for modified radical neck dissection in papillary thyroid carcinoma. Arch Surg 144:567-574
31. Kebebew E, Greenspan FS, Clark OH, Woeber KA, Grunwell J 2005 Extent of disease and practice patterns for medullary thyroid cancer. J Am Coll Surg 200:890-896 (Pubitemid 40744797)
32. Kebebew E, Kikuchi S, Duh QY, Clark O 2000 Long-term results of reoperations and localization studies in patients with persistent or recurrent medullary thyroid cancer. Arch Surg 135:895-901 (Pubitemid 30625965)