Zearalenone is bioactivated in the river Buffalo (Bubalus bubalis): Hepatic biotransformation

Tropical Animal Health and Production

Volumn 42, Issue 6, 2010, Pages 1229-1234

  Hassan, Malekinejad ^a   Fatemeh, Rahmani ^b   Kobra, Bahrampour ^a  

^a URMIA UNIVERSITY   (Iran)

^b URMIA UNIVERSITY   (Iran)

Author keywords

Glucuronidation; Hepatic biotransformation; River buffalo; Subcellular fractions; Zearalenone

Indexed keywords

ESTROGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; URIDINE DIPHOSPHATE GLUCURONIC ACID; ZEARALENONE; ZERANOL;

ANIMAL; ARTICLE; BIOTRANSFORMATION; BUFFALO; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; LIVER; METABOLISM; MICROSOME; PHYSIOLOGY;

ANIMALS; BIOTRANSFORMATION; BUFFALOES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTROGENS, NON-STEROIDAL; KINETICS; LIVER; MICROSOMES; NADP; URIDINE DIPHOSPHATE GLUCURONIC ACID; ZEARALENONE; ZERANOL;

ANIMALIA; BOS; BOVIDAE; BUBALUS BUBALIS; OVIS ARIES;

EID: 77954459072     PISSN: 00494747     EISSN: 15737438     Source Type: Journal    
DOI: 10.1007/s11250-010-9554-x     Document Type: Article

References (27)

1. Amaral M. E. J., Grant J. R., Riggs, P. K., Stafuzza, N. B., Filho, E. A. R., Goldammer, T., Weikard, R., Brunner, R. M., Kochan, K. J., Greco, AJ., Jeong, J., Cai, Z., Lin, G., Prasad, A., Kumar, S., Saradhi, GP., Mathew, B., Kumar, M. A., Miziara, M. N., Mariani, P., Caetano, A. R., Galvão, S. R., Tantia, M. S., Vijh, R. K., Mishra, B., Kumar, STB., Pelai, V. A., Santana, A. M., Fornitano, L. C., Jones, B. C., Tonhati, H., Moore, S., Stothard, P., and Womack, J. E., 2008. A first generation whole genome RH map of the river buffalo with comparison to domestic cattle. BMC Genomics 9, 631-641.
2. Barile, V. L., 2005. Improving reproductive efficiency in female buffaloes. Livestock Production Science 92, 183-194.
3. Belanger, A., Couture, J., Caron, S., and Roy, R., 1990. Determination of non-conjugated and conjugated steroid levels in plasma and prostrate after separation on C-18 columns. Annals of the New York Academy of Sciences 595, 251-259.
4. Boerboom, D., and Sirois, J., 2001. Equine P450 cholesterol side-chain cleavage and 3 beta-hydroxysteroid dehydrogenase/delta (5)-delta (4) isomerase: molecular cloning and regulation of their messenger ribonucleic acids in equine follicles during the ovulatory process. Biology of Reproduction 64, 206-215.
5. Chavatte, P. M., Rossdale, P. D., and Tait, A. D., 1995. Modulation of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) activity in the equine placenta by pregnenolone and progesterone metabolites. Equine Veterinary Journal 27, 342-347.
6. Danicke, S., Matthaus, K., Lebzien, P., Valenta, H., Stemme, K., Ueberschar, K. H., Razzazi-Fazeli, E., Bohm J., and Flachowsky, G., 2005. Effects of Fusarium toxin-contaminated wheat grain on nutrient turnover, microbial protein synthesis and metabolism of deoxynivalenol and zearalenone in the rumen of dairy cows. Journal of Animal Physiology and Animal Nutrition (Berl) 89, 303-315.
7. Di Berardino, D., and Iannuzzi, L., 1981. Chromosome banding homologies in swamp and Murrah buffalo. The Journal of Heredity 72, 183- 188.
8. Driehuis, F., Spanjer, M. C., Scholten, J. M., te Giffel, M. C., and Driehuis F., 2008. Occurrence of mycotoxins in feedstuffs of dairy cows and estimation of total dietary intakes. Journal of Dairy Science 91, 4261-4271.
9. Garon, D., Richard, E., Sage, L., Bouchart, V., Pottier, D., and Lebailly, P., 2006. Mycoflora and multimycotoxin detection in corn silage: experimental study. Journal of Agriculture and Food Chemistry 54, 3479-3484.
10. Gutzwiller, A., Gafner, J. L., and Stoll, P., 2009. Effects of a diet containing fusarium toxins on the fertility of gilts and on bulbourethral gland weight in barrows. Archives of Animal Nutrition 63, 16-25.
11. Hartmann, N., Erbs, M., Forrer, H. R., Vogelgsang, S., Wettstein, F. E., Schwarzenbach, R. P., and Bucheli, T. D., 2008. Occurrence of zearalenone on Fusarium graminearum infected wheat and maize fields in crop organs, soil, and drainage water. Environmental Science & Technology 42, 5455-5460.
12. Hestbjerg, H., Nielsen, K. F., Thrane, U., and Elmholt, S., 2002. Production of trichothecenes and secondary metabolites by Fusarium culmorum and Fusarium equiseti on common laboratory media and a soil organic matter agar: an ecological interpretation. Journal of Agriculture and Food Chemistry 50, 7593-7599.
13. Jakimiuk, E., Jakimiuk, E., Gajecka, M., Jana, B., Brzuzan, P., Zielonka, L., Skorska-Wyszynska, E., and Gajecki, M., 2009. Factors determining sensitivity of prepubertal gilts to hormonal influence of zearalenone. Polish Journal of Veterinary Science 12, 149-58.
14. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., 1951. Protein measurement with the Folin phenol reagent. Journal of Biology and Chemistry 193, 265-275.
15. Malekinejad, H., Maas-Bakker, R. F., and Fink-Gremmels, J., 2005. Bioactivation of zearalenone by porcine hepatic biotransformation. Veterinary Research 36, 799-810.
16. Malekinejad, H., Maas-Bakker, R. F., and Fink-Gremmels, J., 2006a. Species differences in the hepatic biotransformation of Zearalenone. The Veterinary Journal 172, 96-102.
17. Malekinejad, H., Colenbrander, B., and Fink-Gremmels, J., 2006b. Hydroxysteroid dehydrogenases in bovine and porcine granulosa cells convert Zearalenone into its hydroxylated a-zearalenol and β-zearalenol. Veterinary Research Communication 30, 445-453.
18. Malekinejad, H., van Tol, H. T. A., Colenbrander, B., and Fink-Gremmels, J., 2006c. Expression of 3a- and 3b-hydroxy steroid dehydrogenase mRNA in COCs and granulosa cells determines Zearalenone biotransformation. Toxicology in Vitro 20, 458-463.
19. Olsen, M., and Kiessling, K. H., 1983. Species differences in zearalenone-reducing activity in subcellular fractions of liver from female domestic animals. Acta Pharmacology Toxicology (Copenhagen) 52, 287-291.
20. Penning, T. M., Pawlowski, J. E., Schlegel, B. P., Jez, J. M., Lin, H. K., Hoog, S. S., Bennett, M. J., and Lewis, M., 1996. Mammalian 3 alpha-hydroxysteroid dehydrogenases. Steroids 61, 508-523.
21. Perera, B. M. A. O., 1999. Reproduction in water buffalo: comparative aspects and implications for anagement. Journal of Reproduction and Fertility 54, 157-168.
22. Perera, B. M. A. O., 2008. Reproduction in Domestic Buffalo. Reproduction in Domestic Animals 43, 200-206.
23. Pirog, E. C., and Collins, D. C., 1999. Metabolism of dihydrotestosterone in human liver: importance of 3alpha- and 3beta-hydroxysteroid dehydrogenase. Journal of Clinical Endocrinology and Metabolism 84, 3217-3221.
24. Saremi, H., and Okhovvat, S. M., 2006. Mycotoxin producing Fusarium species associated with plant disease on potato, wheat, corn and animal diseases in northwest Iran. Communication in Agriculture and Applied Biological Science 71, 1175-1185.
25. Thomas, J. L., Mason, J. I., Brandt, S., Spencer, B. R., and Norris, W., 2002. Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity. Journal of Biological Chemistry 277, 42795-42801.
26. Tukey, R. H., and Strassburg, C. P., 2000. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual Review of Pharmacology and Toxicology 40, 581-616.
27. Vrabcheva, T., Gessler, R., Usleber, E., and Martlbauer, E., 1996. First survey on the natural occurrence of Fusarium mycotoxins in Bulgarian wheat. Mycopathologia 136, 47-52.