Dual crosslinked pH- and temperature-sensitive hydrogel beads for intestine-targeted controlled release

Polymers for Advanced Technologies

Volumn 21, Issue 5, 2010, Pages 348-355

  Ma, Liwei ^a   Liu, Mingzhu ^a   Liu, Hongliang ^a   Chen, Jun ^a   Gao, Chunmei ^a   Cui, Dapeng ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Carboxymethyl chitosan; Graft; Intestine targeted controlled release; Ionic crosslinking; Temperature and pH sensitive

Indexed keywords

ACIDIC SOLUTIONS; BUFFER SOLUTIONS; CARBOXYMETHYL CHITOSAN; CONTROLLED RELEASE; CROSS-LINKED BEADS; CROSS-LINKED HYDROGELS; CROSSLINKED; CROSSLINKED NETWORK STRUCTURE; DRUG RELEASE MECHANISM; DRUG-RELEASE RATE; GASTROINTESTINAL TRACT; HYDROGEL BEADS; IN-VITRO; IONIC CROSSLINKING; MODEL DRUGS; PH SENSITIVE; PH VALUE; PHOSPHATE BUFFER SOLUTIONS; POLY(N , N-DIETHYLACRYLAMIDE); POTENTIAL EQUATION; RELEASE BEHAVIORS; SEM; SITE-SPECIFIC; SWELLING CHARACTERISTICS; TEMPERATURE-SENSITIVE; TEMPERATURE-SENSITIVE HYDROGELS; VITAMIN B;

CALCIUM; CHITIN; CHITOSAN; DIFFERENTIAL SCANNING CALORIMETRY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FOURIER TRANSFORMS; GRAFTING (CHEMICAL); HYDROCHLORIC ACID; HYDROGELS; SCANNING ELECTRON MICROSCOPY; WAVELET TRANSFORMS;

PH EFFECTS;

CHITOSAN; CROSS LINKING; GRAFTING; HYDROGEL; MORPHOLOGY; PH; SWELLING; TEMPERATURE;

EID: 77954441256     PISSN: 10427147     EISSN: 10991581     Source Type: Journal    
DOI: 10.1002/pat.1434     Document Type: Article

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