Purpura fulminans in a newborn infant with galactosemia

European Journal of Pediatrics

Volumn 169, Issue 7, 2010, Pages 903-906

  Zenciroglu, Aysegul ^a   Ipek, Mehmet Sah ^a   Aydin, Mustafa ^a   Kara, Abdurrahman ^b   Okumus, Nurullah ^a   Kilic, Mustafa ^c  

^a DR SAMI ULUS CHILDREN S HOSPITAL   (Turkey)

^b Dr Sami Ulus Children's Health and Diseases Training and Research Center   (Turkey)

^c HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Galactosemia; Methylenetetrahydrofolate reductase gene mutation; Neonate; Protein C activity; Purpura fulminans

Indexed keywords

ANTIBIOTIC AGENT; FRESH FROZEN PLASMA; GALACTOSE; PROTEIN C; SILVER NITRATE; VITAMIN K GROUP;

ARTICLE; ASCITES; BLOOD COMPONENT; BLOOD CULTURE; BLOOD TRANSFUSION; CASE REPORT; CAUTERIZATION; CEREBROSPINAL FLUID CULTURE; DISEASE ASSOCIATION; DISSEMINATED INTRAVASCULAR CLOTTING; DOPPLER ECHOGRAPHY; ECCHYMOSIS; ECHOCARDIOGRAPHY; ERYTHROCYTE TRANSFUSION; FEMALE; FULMINATING PURPURA; GALACTOSEMIA; GRANULATION TISSUE; HEMATOMA; HEMOSTASIS; HEPATOSPLENOMEGALY; HUMAN; IMMUNOASSAY; INFANT; LABORATORY TEST; LEUKOKORIA; LIVER DISEASE; METABOLIC DISORDER; MUCOSAL BLEEDING; MUSCLE HYPOTONIA; NEWBORN; NEWBORN DISEASE; NEWBORN JAUNDICE; PHOTOTHERAPY; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; PSYCHOMOTOR RETARDATION; SCAR FORMATION; SEPTICEMIA; SEROLOGY; SKIN DEFECT; THIGH; THROMBOCYTE FREE PLASMA; THROMBOCYTE TRANSFUSION; THROMBOSIS; TREATMENT OUTCOME; URINE CULTURE;

FEMALE; GALACTOSEMIAS; HUMANS; INFANT, NEWBORN; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MUTATION; PROTEIN C; PURPURA FULMINANS;

EID: 77954424206     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-009-1121-y     Document Type: Article

References (17)

1. DM Adcock J Brozna RA Marlar 1990 Proposed classification and pathologic mechanisms of purpura fulminans and skin necrosis Semin Thromb Hemost 16 333 340 10.1055/s-2007-1002686 1:STN:280:DyaK3M7is1Cqsg%3D%3D 2281322
2. DM Adcock MJ Hicks 1990 Dermatopathology of skin necrosis associated with purpura fulminans Semin Thromb Hemost 16 283 292 10.1055/s-2007-1002681 1:STN:280:DyaK3M7is1Crtw%3D%3D 2281318
3. L Amitrano MA Guardascione V Brancaccio A Balzano 2002 Coagulation disorders in liver disease Semin Liver Dis 22 83 96 10.1055/s-2002-23205 1:CAS:528:DC%2BD38XislCgtbY%3D 11928081
4. AM Bosch 2006 Classical galactosemia revisited J Inherit Metab Dis 29 516 525 10.1007/s10545-006-0382-0 1:CAS:528:DC%2BD28Xnsl2ju7k%3D 16838075 (Pubitemid 44193265)
5. GL Darmstadt 1998 Acute infectious purpura fulminans: pathogenesis and medical management Pediatr Dermatol 15 169 183 10.1046/j.1525-1470.1998. 1998015169.x 1:STN:280:DyaK1czhvVSitQ%3D%3D 9655311 (Pubitemid 28277976)
6. NA Goldenberg MJ Manco-Johnson 2008 Protein C deficiency Haemophilia 14 1214 1221 1:CAS:528:DC%2BD1MXkt1alsQ%3D%3D 19141162
7. A Gurgey S Aytac G Kanra, et al. 2005 Outcome in children with purpura fulminans: report on 16 patients Am J Hematol 80 20 25 10.1002/ajh.20435 16138355 (Pubitemid 41254263)
8. M Levi CH Toh J Thachil HG Watson 2009 Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Hematology Br J Hematol 145 24 33 10.1111/j.1365-2141.2009.07600.x 1:STN:280:DC%2BD1M3hsVWltQ%3D%3D
9. T Lisman FW Leebeek 2007 Hemostatic alterations in liver disease: a review on pathophysiology, clinical consequences, and treatment Dig Surg 24 250 258 10.1159/000103655 17657149 (Pubitemid 47174040)
10. C Minutillo PJ Pemberton ML Willoughby, et al. 1990 Neonatal purpura fulminans and transient protein C deficiency Arch Dis Child 65 561 562 10.1136/adc.65.5.561-b 1:STN:280:DyaK3c3ptVarsw%3D%3D 2357107
11. J Nolan R Sinclair 2001 Review of management of purpura fulminans and two case reports Br J Anaesth 86 581 586 10.1093/bja/86.4.581 1:STN:280: DC%2BD3MrislKrug%3D%3D 11573639 (Pubitemid 32266326)
12. PG Northup V Sundaram MB Fallon Coagulation in Liver Disease Group, et al. 2008 Hypercoagulation and thrombophilia in liver disease J Thromb Haemost 6 2 9 1:STN:280:DC%2BD1c7gtF2nug%3D%3D 17892532
13. JG Ray D Shmorgun WS Chan 2002 Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies Pathophysiol Haemost Thromb 32 51 58 10.1159/000065076 1:CAS:528:DC%2BD38XlsFOmsb4%3D 12214149 (Pubitemid 37490507)
14. P Reverdiau-Moalic B Delahousse G Body, et al. 1996 Evolution of blood coagulation activators and inhibitors in the healthy human fetus Blood 88 900 906 1:CAS:528:DyaK28Xks1CjtLo%3D 8704247
15. A Veldman MF Nold I Michel-Behnke 2008 Thrombosis in the critically ill neonate: incidence, diagnosis, and management Vasc Health Risk Manag 4 1337 1348 19337547
16. JH Walter JE Collins JV Leonard 1999 Recommendations for the management of galactosemia UK Galactosemia Steering Group. Arch Dis Child 80 93 96 10.1136/adc.80.1.93 1:STN:280:DyaK1M3lslKhsw%3D%3D
17. MJ Welton 1972 Local 'Schwartzman equivalent' reaction in active chronic hepatitis Gut 13 43 46 10.1136/gut.13.1.43