Protection against X-ray radiation-induced cellular damage of human peripheral blood lymphocytes by an aminothiazole derivative of dendrodoine

Chemico-Biological Interactions

Volumn 186, Issue 3, 2010, Pages 267-274

  Kalpana, K B ^a   Devipriya, N ^a   Thayalan, K ^b   Menon, Venugopal P ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b Dr Kamakshi Memorial Hospital   (India)

Author keywords

Aminothiazole derivative; Dendrodoine analog (DA); Lymphocytes; X ray radiation

Indexed keywords

4 AMINO 5 BENZOYL 2 (4 METHOXYPHENYLAMINO)THIAZOLE; ANTIOXIDANT; CATALASE; DENDRODOINE DERIVATIVE; GLUTATHIONE PEROXIDASE; LIPID; SUPEROXIDE DISMUTASE; THIAZOLE DERIVATIVE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CELL ISOLATION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG EFFICACY; DRUG EXPOSURE; DRUG SYNTHESIS; GENETIC DAMAGE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIPID PEROXIDATION; MICRONUCLEUS TEST; PERIPHERAL LYMPHOCYTE; RADIATION PROTECTION; X RAY;

ADULT; ANTIOXIDANTS; CELLS, CULTURED; COMET ASSAY; DNA FRAGMENTATION; HUMANS; INDOLES; LIPID PEROXIDATION; LYMPHOCYTES; RADIATION-PROTECTIVE AGENTS; THIADIAZOLES; THIAZOLES; X-RAYS; YOUNG ADULT;

EID: 77954385943     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.05.003     Document Type: Article

References (40)

1. Jagetia G.C., Rajanikant G.K., Rao S.K., Shrinath Baliga M. Alteration in the glutathione, glutathione peroxidase, superoxide dismutase and lipid peroxidation by ascorbic acid in the skin of mice exposed to fractionated γ-radiation. Clin. Chim. Acta 2003, 332:111-121.
2. Jagetia G.C., Reddy T.K. Modulation of radiation induced alterations in the antioxidant status of mice by naringin. Life Sci. 2005, 77:780-794.
3. Nair C.K.K., Parida D.K., Noumra T. Radioprotectors in radiotherapy. J. Radiat. Res. 2001, 42:21-37.
4. Von Sonntag The Chemical Basis of Radiation Biology 1987, Taylor and Francis, London.
5. Spotheim-Maurizot M., Gariner F., Sabattier R., Charlier M. Metal ions protects DNA against strand breakage induced by fast neutrons. Int. J. Radiat. Biol. 1992, 62:659-666.
6. Piperakis S.M., Visvardis E.E., Tassiou A.M. Comet assay for nuclear DNA damage. Methods Enzymol. 1999, 300:184-194.
7. Maluf S.W. Monitoring DNA damage following radiation exposure using cytokinesis-block micronucleus method and alkaline single-cell gel electrophoresis. Clin. Chim. Acta 2004, 347:15-24.
8. Mittal A., Pathania V., Agrawala P.K., Prasad J., Singh S., Goel H.C. Influence of Podophyllum hexandrum on endogenous antioxidant defense system in mice: possible role in radioprotection. J. Ethnopharmocol. 2001, 76:253-262.
9. Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 1992, 59:1609-1623.
10. Agrawal A., Kale R.K. Radiation induced peroxidative damage: mechanism and significance. Indian J. Exp. Biol. 2001, 39:209-291.
11. Pandey B.N., Mishra K.P. Fluorescence and ESR studies on membrane oxidative damage by γ-radiation. Appl. Magn. Reson. 2000, 18:483-492.
12. Heitz S., Durgeat M., Guyot M., Brassy C., Bachet B. Nouveau derive indolique du thiadiazole-1, 2,4,isole d'un tunicier (Dendrodoa grossularia). Tetrahedron Lett. 1980, 21:1457-1458.
13. Hogan I.T., Sainsbury M. Synthesis of 1,2,4-thiazole derivative, dendroine. Tetrahedron 1984, 40:681-682.
14. Ohkubo M., Kono A., Nakanishi I., Takasughi H. Studies on cerebral protective agents: synthesis of 2-aminothiazoles and 2-thiazole-carboxamides with antianoxic activity. Chem. Pharm. 1995, 43:1497-1504.
15. Uchikawa O., Fukatsu K., Suno M., Aono T., Doi T. In vivo biological activity of antioxidative aminothiazole derivatives. Chem. Pharm. Bull. 1996, 44:2070-2077.
16. Rajasekaran K.N., Nair K.P., Jenardanan G.C. Studies on the synthesis of 5-acyl-2,4-diaminothiazoles from amidinothioureas. Synthesis 1987, 5:353-355.
17. Boyum A. Isolation of mononuclear cells and granulocytes from human blood. J. Clin. Lab. Invest. 1968, (Suppl. 21):77-89.
18. Rajendra Prasad N., Menon V.P., Vasudev V., Pugalendi K.V. Radioprotective effect of seasamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants level in cultured human lymphocytes. Toxicology 2005, 209:25-335.
19. Fenech M.A, Morely A.A. Measurement of micronuclei in lymphocytes. Mutat. Res. 1985, 147:29-36.
20. Countryman P.I., Heddle J.A. The production of MN from chromosome aberrations in irradiated culture of human lymphocytes. Mutat. Res. 1976, 41:321-332.
21. Singh N.P. Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis. Mutat. Res. 2000, 455:111-127.
22. Niehans W.G., Samuelson B. Formation of malondialdehyde from phospholipids arachidonate during microsomal lipid peroxidation. Eur. J. Biochem. 1968, 6:126-130.
23. Kakkar P., Das B., Viswanathan P.N. A modified spectrophotometric assay of superoxide dismutase (SOD). Indian J. Biochem. Biophys. 1984, 21:130-132.
24. Sinha K.A. Colorimetric assay of catalase. Anal. Biochem. 1972, 47:89-394.
25. Rotruck J.T., Pope A., Ganther H.E., Swanson A.B. Selenium: biochemical roles as component of glutathione peroxidase. Science 1973, 179:588-590.
26. Ellman G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 1959, 82:70-77.
27. Hebert M., Takano T., Holthoefer H., Brady H.R. Sequential morphologic events during apoptosis of human neutrophils. J. Immunol. 1996, 157:3105-3115.
28. Molecular Cloning: A Laboratory Manual 1989, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. 2nd ed. J.E. Sambrook, F. Fritsch, T. Maniatis, C. Nolan (Eds.).
29. Lacombe S., Le Sech C. Advances in radiation biology: radiosensitization in DNA and living cells. Surf. Sci. 2009, 603:1953-1960.
30. Mayer C., Popanda O., Zeleny O. DNA repair capacity after γ-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes. DNA Repair 2002, 1:237-250.
31. 60 gamma-ray dose-response. Mutat. Res. 1996, 359:151-157.
32. Park J.E., Lee K.J., Kim C. Thermo-tolerance inhibits various stress-induced apoptosis in NIH3T3 cells. Arch. Pharm. Res. 1998, 21:46-53.
33. De S., Adhikari S., Tilak-Jain J., Menon V.P., Devasagayam T.P. Antioxidant activity of an aminothiazole compound: possible mechanisms. Chem. Biol. Interact. 2008, 173:215-223.
34. Gerster H. β-Carotene, Vitamin E and Vitamin C in different stages of experimental carcinogenesis. Eur. J. Clin. Nutr. 1995, 49:155-168.
35. Dinkova-Kostova A.T. Protection against cancer by plant phenyl propenoids: induction of mammalian anti-carcinogenic enzymes. Mini-Rev. Med. Chem. 2002, 2:595-610.
36. Dubner D., Gione P., Jaitovich I., Pere Z.M. Free radicals production and estimation of oxidative stress related to γ-irradiation. Biol. Trace Elem. Res. 1995, 47:265.
37. Kalpana K.B., Devipriya N., Srinivasan M., Menon V.P. Investigation of the radioprotective efficacy of hesperidin against gamma-radiation induced cellular damage in cultured human peripheral blood lymphocytes. Mutat. Res. 2009, 676:54-61.
38. Aruna K., Rukkumani R., Suresh Varma P., Menon V.P. Influence of a thiazole derivative on ethanol and thermally oxidized sunflower oil-induced oxidative stress. Pol. J. Pharmacol. 2004, 56:233-240.
39. Mensor L.L., Menezes S.F., Leitao G.G., Reis S.A., Santos C.T., Coube S.C. Antioxidant activity in Brazilian plants. Phytother. Res. 2001, 15:127-130.
40. Kalpana K.B., Srinivasan M., Menon V.P. Antioxidant potential of aminothiazole derivative and its protective effect on H(2)O(2)-induced oxidative damage on pBR322 DNA and RBC cellular membrane. Mol. Cell. Biochem. 2008, 314:95-103.