In vivo biological activity of antioxidative aminothiazole derivatives

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 11, 1996, Pages 2070-2077

  Uchikawa, Osamu ^a   Fukatsu, Kohji ^a   Suno, Masahiro ^a   Aono, Tetsuya ^a   Doi, Takayuki ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

antioxidant; central nervous system; iron(II) chloride intrathecal injection; thiazoloazepine; thiazolopyridine

Indexed keywords

ANTIOXIDANT; AZEPINE DERIVATIVE; LACTAM; PYRIDINE DERIVATIVE; THIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG ACTIVITY; IN VIVO STUDY; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION;

EID: 0029956006     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.2070     Document Type: Article

References (25)

1. Braughler J. M., Hall E. D., Free Radicals Biol. Med., 6, 289-301 (1989).
2. Jacobsen E. J., Van Doornik F. J., Ayer D. E., Belonga K. L., Braughler J. M., Hall E. D., Houser D. J., J. Med. Chem., 35, 4464-4472 (1992).
3. Hall E. D., Braughler J. M., Yonkers P. A., Smith S. L., Linseman K. L., Means E. D., Scherch H. M., Von Voightlander P. F., Lahti R. A., Jacobsen E. J., J. Pharmacol. Exp. Ther., 258, 688-694 (1991).
4. Saunders R. D., Dugan L. L., Demediuk P., Means E. D., Horrocks L. A., Anderson D. K., J. Neurochem., 49, 24-31 (1987).
5. Harrison S. C., Lynch J. J., Rose K., Choi D. W., Brain Res., 639, 102-108 (1994).
6. Halliwell B., J. Neurochem., 59, 1609-1623 (1992).
7. Willmore L. J., Hurd R. W., Sypert G. W., Brain Res., 152, 406-410 (1978).
8. Willmore L. J., Hiramatsu M., Kochi H., Mori A., Brain Res., 277, 393-396 (1983).
9. Willmore L. J., Rubin J. J., Exp. Neurol., 83, 62-70 (1984).
10. Willmore L. J., Sypert G. W., Munson J. B., Hurd R. W., Science, 200, 1501-1503 (1978).
11. Subbarao K. V., Richardson J. S., J. Neurosci. Res., 26, 224-232 (1990).
12. Colombo J. A., Whitmoyer D. I., Sawyer C. H., Brain Res., 96, 88-92 (1975).
13. Doi T., Kuzuna S., Maki Y., Eur. J. Pharmacol., 137, 227-232 (1987).
14. Uchikawa O., Fukatsu K., Aono T., J. Heterocyclic Chem., 31, 877-887 (1994).
15. Uchikawa O., Aono T., J. Heterocycl. Chem., 31, 1545-1551 (1994).
16. Pellegata R., Pinza M., Pifferi G., Synthesis, 1978, 614-616.
17. Blade-Font, Tetrahedron Lett., 1980, 2443-2446.
18. Winter W., Graudums I., Frankus E., Liebigs Ann. Chem., 2021 -2028 (1983).
19. Nagasawa H. T., Elberling J. A., Fraser P. S., J. Med. Chem., 14, 501-508 (1971).
20. Wineman R. J., Hsu E.-P. T., Anagnostopoulos C. E., J. Am. Chem. Soc., 80, 6233-6237 (1958).
21. Thorsett E. D., Harris E. E., Aster S. D., Peterson E. R., Snyder J. P., Springer J. P., Hirshfield J., Tristram E. W., Pachett A. A., Ulm E. H., Vassil T. C., J. Med. Chem., 29, 251-260 (1986).
22. Boyer S. K., Pfund R. A., Portmann R. E., Sedelmeier G. H., Wetter H. F., Helv. Chim. Acta, 71, 337-343 (1988).
23. Pappalardo G., Tornetta B., Scapini G., Farmaco. Ed. Sci., 21, 740-748 (1966).
24. Stocks J., Gutteridge J. M. C., Sharp R. J., Dormandy T. L., Clin. Sci. Mol. Med., 47, 215-222 (1974).
25. Ohkawa H., Ohishi N., Yagi K., Anal. Biochem., 95, 351-358 (1979).