Anemia is associated with metabolic distress and brain tissue hypoxia after subarachnoid hemorrhage

Neurocritical Care

Volumn 13, Issue 1, 2010, Pages 10-16

  Kurtz, Pedro ^a,b   Schmidt, J Michael ^a   Claassen, Jan ^a   Carrera, Emmanuel ^a   Fernandez, Luis ^a   Helbok, Raimund ^a   Presciutti, Mary ^a   Stuart, R Morgan ^a   Connolly, E Sander ^a   Badjatia, Neeraj ^a   Mayer, Stephan A ^a   Lee, Kiwon ^a  

^a Milstein Hospital   (United States)

^b Intensive Care Unit   (Brazil)

Author keywords

Anemia; Brain injury; Brain tissue oxygen; Cerebral microdialysis; Subarachnoid hemorrhage

Indexed keywords

GLUCOSE; HEMOGLOBIN; OXYGEN;

ADULT; AGED; ANEMIA; ARTICLE; BLOOD GAS ANALYSIS; BRAIN HYPOXIA; BRAIN METABOLISM; BRAIN TISSUE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTRACRANIAL PRESSURE; MALE; METABOLIC DISORDER; OXYGEN TISSUE LEVEL; OXYGENATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SUBARACHNOID HEMORRHAGE; VASOSPASM; BLOOD; BRAIN; COMPLICATION; HYPOXIA, BRAIN; METABOLIC DISEASES; METABOLISM; MICRODIALYSIS; MIDDLE AGED; OSMOLARITY; RISK ASSESSMENT; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANEMIA; BRAIN; FEMALE; HEMOGLOBINS; HUMANS; HYPOXIA, BRAIN; MALE; METABOLIC DISEASES; MICRODIALYSIS; MIDDLE AGED; OSMOLAR CONCENTRATION; OXYGEN; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SUBARACHNOID HEMORRHAGE;

EID: 77954385617     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-010-9357-y     Document Type: Article

References (37)

1. HL Corwin A Gettinger RG Pearl, et al. 2004 The CRIT Study: anemia and blood transfusion in the critically ill-current clinical practice in the United States Crit Care Med 32 39 52 10.1097/01.CCM.0000104112.34142.79 14707558
2. JL Vincent JF Baron K Reinhart, et al. 2002 Anemia and blood transfusion in critically ill patients JAMA 288 1499 1507 10.1001/jama.288.12.1499 12243637
3. AH Kramer DA Zygun TP Bleck AS Dumont NF Kassell B Nathan 2009 Relationship between hemoglobin concentrations and outcomes across subgroups of patients with aneurysmal subarachnoid hemorrhage Neurocrit Care 10 157 165 10.1007/s12028-008-9171-y 19116699
4. MV Springer JM Schmidt KE Wartenberg JA Frontera N Badjatia SA Mayer 2009 Predictors of global cognitive impairment 1 year after subarachnoid hemorrhage Neurosurgery 65 1043 1050 10.1227/01.NEU.0000359317.15269.20 19934963 (discussion 50-51)
5. AM Naidech B Jovanovic KE Wartenberg, et al. 2007 Higher hemoglobin is associated with improved outcome after subarachnoid hemorrhage Crit Care Med 35 2383 2389 10.1097/01.CCM.0000284516.17580.2C 17717494 (Pubitemid 47476238)
6. KE Wartenberg JM Schmidt J Claassen, et al. 2006 Impact of medical complications on outcome after subarachnoid hemorrhage Crit Care Med 34 617 623 10.1097/00003246-200612002-00426 16521258 (quiz 24)
7. PC Hebert G Wells MA Blajchman, et al. 1999 A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group N Engl J Med 340 409 417 10.1056/NEJM199902113400601 9971864 (Pubitemid 29084771)
8. GM Hare 2004 Anemia and the brain Curr Opin Anaesthesiol 17 363 369 10.1097/00001503-200410000-00003 17023891 (Pubitemid 39331941)
9. SR Leal-Noval MD Rincon-Ferrari A Marin-Niebla, et al. 2006 Transfusion of erythrocyte concentrates produces a variable increment on cerebral oxygenation in patients with severe traumatic brain injury: a preliminary study Intensive Care Med 32 1733 1740 10.1007/s00134-006-0376-2 17019549 (Pubitemid 44607360)
10. SR Leal-Noval M Munoz-Gomez V Arellano-Orden, et al. 2008 Impact of age of transfused blood on cerebral oxygenation in male patients with severe traumatic brain injury Crit Care Med 36 1290 1296 10.1097/CCM.0b013e3181692dfc 18379257 (Pubitemid 351482680)
11. MJ Smith MF Stiefel S Magge, et al. 2005 Packed red blood cell transfusion increases local cerebral oxygenation Crit Care Med 33 1104 1108 10.1097/01.CCM.0000162685.60609.49 15891343 (Pubitemid 40638186)
12. WA van den Brink H van Santbrink EW Steyerberg, et al. 2000 Brain oxygen tension in severe head injury Neurosurgery 46 868 876 10.1097/00006123- 200004000-00018 10764260 (discussion 76-78)
13. J Meixensberger C Renner R Simanowski A Schmidtke J Dings K Roosen 2004 Influence of cerebral oxygenation following severe head injury on neuropsychological testing Neurol Res 26 414 417 10.1179/016164104225014094 15198869 (Pubitemid 38758465)
14. AB Valadka SP Gopinath CF Contant M Uzura CS Robertson 1998 Relationship of brain tissue PO2 to outcome after severe head injury Crit Care Med 26 1576 1581 10.1097/00003246-199809000-00029 9751596 (Pubitemid 28450368)
15. H van Santbrink WA vd Brink EW Steyerberg JA Carmona Suazo CJ Avezaat AI Maas 2003 Brain tissue oxygen response in severe traumatic brain injury Acta Neurochir (Wien) 145 429 438 (discussion 38)
16. J Meixensberger M Jaeger A Vath J Dings E Kunze K Roosen 2003 Brain tissue oxygen guided treatment supplementing ICP/CPP therapy after traumatic brain injury J Neurol Neurosurg Psychiatry 74 760 764 10.1136/jnnp.74.6.760 12754347 (Pubitemid 36628290)
17. JC Hemphill III D Morabito M Farrant GT Manley 2005 Brain tissue oxygen monitoring in intracerebral hemorrhage Neurocrit Care 3 260 270 10.1385/NCC:3:3:260 16377842 (Pubitemid 43004824)
18. AJ Johnston LA Steiner JP Coles, et al. 2005 Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury Crit Care Med 33 189 195 10.1097/01.CCM.0000149837.09225.BD 15644668 (discussion 255-257) (Pubitemid 40116556)
19. M Carvi y Nievas S Toktamis HG Hollerhage E Haas 2005 Hyperacute measurement of brain-tissue oxygen, carbon dioxide, pH, and intracranial pressure before, during, and after cerebral angiography in patients with aneurysmatic subarachnoid hemorrhage in poor condition Surg Neurol 64 362 367 10.1016/j.surneu.2005.02.008 16182009 (discussion 7) (Pubitemid 41337905)
20. MK Schulz LP Wang M Tange P Bjerre 2000 Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage J Neurosurg 93 808 814 10.3171/jns.2000.93.5.0808 11059662
21. P Vespa M Bergsneider N Hattori, et al. 2005 Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study J Cereb Blood Flow Metab 25 763 774 10.1038/sj.jcbfm.9600073 15716852 (Pubitemid 40705611)
22. C Samuelsson L Hillered M Zetterling, et al. 2007 Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients J Cereb Blood Flow Metab 27 1309 1317 10.1038/sj.jcbfm.9600433 17228333 (Pubitemid 46985347)
23. M Oddo A Milby I Chen, et al. 2009 Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage Stroke 40 1275 1281 10.1161/STROKEAHA.108.527911 19265059
24. L Hillered PM Vespa DA Hovda 2005 Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis J Neurotrauma 22 3 41 10.1089/neu.2005.22.3 15665601
25. BM Bellander E Cantais P Enblad, et al. 2004 Consensus meeting on microdialysis in neurointensive care Intensive Care Med 30 2166 2169 10.1007/s00134-004-2461-8 15549254 (Pubitemid 40174251)
26. SL Bratton RM Chestnut J Ghajar 2007 et al. Guidelines for the management of severe traumatic brain injury. XV. Steroids J Neurotrauma 24 Suppl 1 S91 S95 17511554
27. JB Bederson ES Connolly Jr HH Batjer, et al. 2009 Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association Stroke 40 994 1025 10.1161/STROKEAHA.108.191395 19164800
28. J Broderick S Connolly E Feldmann, et al. 2007 Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group Circulation 116 e391 e413 10.1161/CIRCULATIONAHA.107.183689 17938297
29. N Badjatia E Strongilis E Gordon, et al. 2008 Metabolic impact of shivering during therapeutic temperature modulation: the Bedside Shivering Assessment Scale Stroke 39 3242 3247 10.1161/STROKEAHA.108.523654 18927450
30. W Pan 2001 Model selection in estimating equations Biometrics 57 529 534 10.1111/j.0006-341X.2001.00529.x 11414579
31. W Pan 2001 Akaike's information criterion in generalized estimating equations Biometrics 57 120 125 10.1111/j.0006-341X.2001.00120.x 11252586
32. C Robertson 1993 Desaturation episodes after severe head injury: influence on outcome Acta Neurochir Suppl (Wien) 59 98 101
33. J Cruz 1998 The first decade of continuous monitoring of jugular bulb oxyhemoglobin saturation: management strategies and clinical outcome Crit Care Med 26 344 351 10.1097/00003246-199802000-00039 9468174 (Pubitemid 28082698)
34. CS Robertson SP Gopinath JC Goodman CF Contant AB Valadka RK Narayan 1995 SjvO2 monitoring in head-injured patients J Neurotrauma 12 891 896 10.1089/neu.1995.12.891 8594216
35. GM Hare CD Mazer JS Hutchison, et al. 2007 Severe hemodilutional anemia increases cerebral tissue injury following acute neurotrauma J Appl Physiol 103 1021 1029 10.1152/japplphysiol.01315.2006 17556499 (Pubitemid 47358889)
36. G Rosenthal D Morabito M Cohen, et al. 2008 Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation J Neurosurg 108 575 587 10.3171/JNS/2008/108/3/0575 18312106 (Pubitemid 351357991)
37. S Stern J Rice N Philbin, et al. 2009 Resuscitation with the hemoglobin-based oxygen carrier, HBOC-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury Shock 31 64 79 10.1097/SHK.0b013e3181778dc3 18497706