Brain volume alteration and the correlations with the clinical characteristics in drug-naïve first-episode MDD patients: A voxel-based morphometry study

Neuroscience Letters

Volumn 480, Issue 1, 2010, Pages 30-34

  Cheng, Yu Qi ^a,b,c   Xu, Jian ^c   Chai, Pei ^d   Li, Hai Jun ^e   Luo, Chun Rong ^e   Yang, Tao ^c   Li, Lin ^d   Shan, Bao Ci ^d   Xu, Xiu Feng ^c   Xu, Lin ^a,b  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c KUNMING MEDICAL UNIVERSITY   (China)

^d INSTITUTE OF HIGH ENERGY PHYSICS   (China)

^e First Hospital of Kunming City   (China)

Author keywords

Adult onset; Drug na ve; First episode; Major depressive disorder; Neuroimaging

Indexed keywords

ADULT; ARTICLE; BRAIN ISCHEMIA; BRAIN SIZE; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; EMPTY SELLA SYNDROME; FEMALE; GRAY MATTER; HIPPOCAMPUS; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MOTOR CORTEX; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; SELLA TURCICA; VOXEL BASED MORPHOMETRY; WHITE MATTER; ADOLESCENT; BRAIN; MIDDLE AGED; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; BRAIN; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; ORGAN SIZE; YOUNG ADULT;

EID: 77954384685     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.05.075     Document Type: Article

References (25)

1. Ballmaier M., Toga A.W., Blanton R.E., Sowell E.R., Lavretsky H., Peterson J., Pham D., Kumar A. Anterior cingulate, gyrus rectus, and orbitofrontal abnormalities in elderly depressed patients: an MRI-based parcellation of the prefrontal cortex. Am. J. Psychiatry 2004, 161:99-108.
2. Colla M., Kronenberg G., Deuschle M., Meichel K., Hagen T., Bohrer M., Heuser I. Hippocampal volume reduction and HPA-system activity in major depression. J. Psychiatr. Res. 2007, 41:553-560.
3. Czeh B., Michaelis T., Watanabe T., Frahm J., de Biurrun G., van Kampen M., Bartolomucci A., Fuchs E. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:12796-12801.
4. Exner C., Lange C., Irle E. Impaired implicit learning and reduced pre-supplementary motor cortex size in early-onset major depression with melancholic features. J. Affect. Disord. 2009, 119:156-162.
5. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0) 1995.
6. Frodl T.S., Koutsouleris N., Bottlender R., Born C., Jager M., Scupin I., Reiser M., Moller H.J., Meisenzahl E.M. Depression-related variation in brain morphology over 3 years: effects of stress?. Arch. Gen. Psychiatry 2008, 65:1156-1165.
7. Frodl T., Meisenzahl E.M., Zetzsche T., Born C., Groll C., Jager M., Leinsinger G., Bottlender R., Hahn K., Moller H.J. Hippocampal changes in patients with a first episode of major depression. Am. J. Psychiatry 2002, 159:1112-1118.
8. Frodl T., Meisenzahl E., Zetzsche T., Bottlender R., Born C., Groll C., Jager M., Leinsinger G., Hahn K., Moller H.J. Enlargement of the amygdala in patients with a first episode of major depression. Biol. Psychiatry 2002, 51:708-714.
9. Koolschijn P.C., van Haren N.E., Lensvelt-Mulders G.J., Hulshoff Pol H.E., Kahn R.S. Brain volume abnormalities in major depressive disorder: a meta-analysis of magnetic resonance imaging studies. Hum. Brain Mapp. 2009, 30:3719-3735.
10. Krishnan K.R., McDonald W.M., Escalona P.R., Doraiswamy P.M., Na C., Husain M.M., Figiel G.S., Boyko O.B., Ellinwood E.H., Nemeroff C.B. Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Arch. Gen. Psychiatry 1992, 49:553-557.
11. Lavretsky H., Roybal D.J., Ballmaier M., Toga A.W., Kumar A. Antidepressant exposure may protect against decrement in frontal gray matter volumes in geriatric depression. J. Clin. Psychiatry 2005, 66:964-967.
12. MacQueen G.M., Campbell S., McEwen B.S., Macdonald K., Amano S., Joffe R.T., Nahmias C., Young L.T. Course of illness, hippocampal function, and hippocampal volume in major depression. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:1387-1392.
13. Maller J.J., Daskalakis Z.J., Fitzgerald P.B. Hippocampal volumetrics in depression: the importance of the posterior tail. Hippocampus 2007, 17:1023-1027.
14. Pizzagalli D.A., Holmes A.J., Dillon D.G., Goetz E.L., Birk J.L., Bogdan R., Dougherty D.D., Iosifescu D.V., Rauch S.L., Fava M. Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder. Am. J. Psychiatry 2009, 166:702-710.
15. Rotzer S., Kucian K., Martin E., von Aster M., Klaver P., Loenneker T. Optimized voxel-based morphometry in children with developmental dyscalculia. Neuroimage 2008, 39:417-422.
16. Sheline Y.I., Sanghavi M., Mintun M.A., Gado M.H. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J. Neurosci. 1999, 19:5034-5043.
17. Sheline Y.I., Wang P.W., Gado M.H., Csernansky J.G., Vannier M.W. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:3908-3913.
18. Steffens D.C., Payne M.E., Greenberg D.L., Byrum C.E., Welsh-Bohmer K.A., Wagner H.R., MacFall J.R. Hippocampal volume and incident dementia in geriatric depression. Am. J. Geriatr. Psychiatry 2002, 10:62-71.
19. Takahashi T., Yucel M., Lorenzetti V., Tanino R., Whittle S., Suzuki M., Walterfang M., Pantelis C., Allen N.B. Volumetric MRI study of the insular cortex in individuals with current and past major depression. J. Affect. Disord. 2009.
20. Taki Y., Kinomura S., Awata S., Inoue K., Sato K., Ito H., Goto R., Uchida S., Tsuji I., Arai H., Kawashima R., Fukuda H. Male elderly subthreshold depression patients have smaller volume of medial part of prefrontal cortex and precentral gyrus compared with age-matched normal subjects: a voxel-based morphometry. J. Affect. Disord. 2005, 88:313-320.
21. Taylor W.D., Steffens D.C., McQuoid D.R., Payne M.E., Lee S.H., Lai T.J., Krishnan K.R. Smaller orbital frontal cortex volumes associated with functional disability in depressed elders. Biol. Psychiatry 2003, 53:144-149.
22. van Eijndhoven P., van Wingen G., van Oijen K., Rijpkema M., Goraj B., Jan Verkes R., Oude Voshaar R., Fernandez G., Buitelaar J., Tendolkar I. Amygdala volume marks the acute state in the early course of depression. Biol. Psychiatry 2009, 65:812-818.
23. Vasic N., Walter H., Hose A., Wolf R.C. Gray matter reduction associated with psychopathology and cognitive dysfunction in unipolar depression: a voxel-based morphometry study. J. Affect. Disord. 2008, 109:107-116.
24. Videbech P., Ravnkilde B. Hippocampal volume and depression: a meta-analysis of MRI studies. Am. J. Psychiatry 2004, 161:1957-1966.
25. Yucel K., McKinnon M.C., Chahal R., Taylor V.H., Macdonald K., Joffe R., MacQueen G.M. Anterior cingulate volumes in never-treated patients with major depressive disorder. Neuropsychopharmacology 2008, 33:3157-3163.