메뉴 건너뛰기




Volumn 24, Issue 2, 2010, Pages 441-448

Gastrin-releasing peptide promotes the growth of HepG2 cells via EGFR-independent ERK1/2 activation

Author keywords

Extracellular signal regulated kinase 1 2; Gastrin releasing peptide; Gastrin releasing peptide receptor; Hepatocellular carcinoma; Mitogen activated protein kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; GASTRIN RELEASING PEPTIDE; GASTRIN RELEASING PEPTIDE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; 4-((3-BROMOPHENYL)AMINO)-6,7-DIMETHOXYQUINAZOLINE; ANTINEOPLASTIC AGENT; BOMBESIN RECEPTOR; EGFR PROTEIN, HUMAN; INDOLE DERIVATIVE; MAPK1 PROTEIN, HUMAN; PD 176252; QUINAZOLINE DERIVATIVE;

EID: 77954361468     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000877     Document Type: Article
Times cited : (15)

References (22)
  • 2
    • 25444521559 scopus 로고    scopus 로고
    • Biologic relevance of mammalian bombesin-like peptides and their receptors in human malignancies
    • Qu X, Xiao D and Weber HC: Biologic relevance of mammalian bombesin-like peptides and their receptors in human malignancies. Curr Opin Endocrinology Diabetes 10: 60-71, 2003.
    • (2003) Curr Opin Endocrinology Diabetes , vol.10 , pp. 60-71
    • Qu, X.1    Xiao, D.2    Weber, H.C.3
  • 3
    • 0026717125 scopus 로고
    • Gastrin-releasing peptide: In vivo and in vitro growth effects on an acinar pancreatic carcinoma
    • Hajri A, Balboni G, Koenig M, Garaud JC and Damge C: Gastrin-releasing peptide: in vivo and in vitro growth effects on an acinar pancreatic carcinoma. Cancer Res 52: 3726-3732, 1992.
    • (1992) Cancer Res , vol.52 , pp. 3726-3732
    • Hajri, A.1    Balboni, G.2    Koenig, M.3    Garaud, J.C.4    Damge, C.5
  • 4
    • 0026802370 scopus 로고
    • Stimulation by bombesin and inhibition by bombesin/gastrin-releasing peptide antagonist RC-3095 of growth of human breast cancer cell lines
    • Yano T, Pinski J, Groot K and Schally AV: Stimulation by bombesin and inhibition by bombesin/gastrin-releasing peptide antagonist RC-3095 of growth of human breast cancer cell lines. Cancer Res 52: 4545-4547, 1992.
    • (1992) Cancer Res , vol.52 , pp. 4545-4547
    • Yano, T.1    Pinski, J.2    Groot, K.3    Schally, A.V.4
  • 6
    • 0032991986 scopus 로고    scopus 로고
    • High gastrin releasing peptide receptor mRNA level is related to tumour dedifferentiation and lymphatic vessel invasion in human colon cancer
    • Saurin JC, Rouault JP, Abello J, Berger F, Remy L and Chayvialle JA: High gastrin releasing peptide receptor mRNA level is related to tumour dedifferentiation and lymphatic vessel invasion in human colon cancer. Eur J Cancer 35: 125-132, 1999.
    • (1999) Eur J Cancer , vol.35 , pp. 125-132
    • Saurin, J.C.1    Rouault, J.P.2    Abello, J.3    Berger, F.4    Remy, L.5    Chayvialle, J.A.6
  • 8
    • 0030759810 scopus 로고    scopus 로고
    • Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer
    • Kelley MJ, Linnoila RI, Avis IL, et al: Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer. Chest 112: 256-261, 1997.
    • (1997) Chest , vol.112 , pp. 256-261
    • Kelley, M.J.1    Linnoila, R.I.2    Avis, I.L.3
  • 9
    • 34548459014 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy
    • DOI 10.1093/annonc/mdm058
    • Cornelio DB, Roesler R and Schwartsmann G: Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy. Ann Oncol 18: 1457-1466, 2007. (Pubitemid 47365477)
    • (2007) Annals of Oncology , vol.18 , Issue.9 , pp. 1457-1466
    • Cornelio, D.B.1    Roesler, R.2    Schwartsmann, G.3
  • 10
    • 0142219315 scopus 로고    scopus 로고
    • Bombesin/Gastrin-Releasing Peptide Receptor: A Potential Target for Antibody-Mediated Therapy of Small Cell Lung Cancer
    • Zhou J, Chen J, Mokotoff M, Zhong R, Shultz LD and Ball ED: Bombesin/gastrin-releasing peptide receptor: a potential target for antibody-mediated therapy of small cell lung cancer. Clin Cancer Res 9: 4953-4960, 2003. (Pubitemid 37323302)
    • (2003) Clinical Cancer Research , vol.9 , Issue.13 , pp. 4953-4960
    • Zhou, J.1    Chen, J.2    Mokotoff, M.3    Zhong, R.4    Shultz, L.D.5    Ball, E.D.6
  • 11
    • 51349137154 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma
    • Qiao J, Kang J, Ishola TA, Rychahou PG, Evers BM and Chung DH: Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma. Proc Natl Acad Sci USA 105: 12891-12896, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 12891-12896
    • Qiao, J.1    Kang, J.2    Ishola, T.A.3    Rychahou, P.G.4    Evers, B.M.5    Chung, D.H.6
  • 12
    • 33846333090 scopus 로고    scopus 로고
    • MicroPET imaging of breast cancer using radiolabeled bombesin analogs targeting the gastrin-releasing peptide receptor
    • Parry JJ, Andrews R and Rogers BE: MicroPET imaging of breast cancer using radiolabeled bombesin analogs targeting the gastrin-releasing peptide receptor. Breast Cancer Res Treat 101: 175-183, 2007.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 175-183
    • Parry, J.J.1    Andrews, R.2    Rogers, B.E.3
  • 13
    • 38949192477 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry
    • Wiele CV, Phonteyne P, Pauwels P, et al: Gastrin-releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry. J Nucl Med 49: 260-264, 2008.
    • (2008) J Nucl Med , vol.49 , pp. 260-264
    • Wiele, C.V.1    Phonteyne, P.2    Pauwels, P.3
  • 14
    • 56649115222 scopus 로고    scopus 로고
    • Novel glycated [99mTc(CO)3]-labeled bombesin analogues for improved targeting of gastrin-releasing peptide receptor-positive tumors
    • SchweinsbergC, Maes V, Brans L, et al: Novel glycated [99mTc(CO)3]-labeled bombesin analogues for improved targeting of gastrin-releasing peptide receptor-positive tumors. Bioconjug Chem 19: 2432-2439, 2008.
    • (2008) Bioconjug Chem , vol.19 , pp. 2432-2439
    • Schweinsberg, C.1    Maes, V.2    Brans, L.3
  • 15
    • 0142025133 scopus 로고    scopus 로고
    • Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor
    • Lui VW, Thomas SM, Zhang Q, et al: Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor. Oncogene 22: 6183-6193, 2003.
    • (2003) Oncogene , vol.22 , pp. 6183-6193
    • Lui, V.W.1    Thomas, S.M.2    Zhang, Q.3
  • 16
    • 9444225949 scopus 로고    scopus 로고
    • Alterations in receptor expression or agonist concentration change the pathways gastrin-releasing peptide receptor uses to regulate extracellular signal-regulated kinase
    • Chen PW and Kroog GS: Alterations in receptor expression or agonist concentration change the pathways gastrin-releasing peptide receptor uses to regulate extracellular signal-regulated kinase. Mol Pharmacol 166: 1625-1634, 2004.
    • (2004) Mol Pharmacol , vol.166 , pp. 1625-1634
    • Chen, P.W.1    Kroog, G.S.2
  • 17
    • 33646468634 scopus 로고    scopus 로고
    • Phosphorylation of TNF-α converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation
    • Zhang Q, Thomas SM, Lui VW, et al: Phosphorylation of TNF-α converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation. Proc Natl Acad Sci USA 103: 6901-6906, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6901-6906
    • Zhang, Q.1    Thomas, S.M.2    Lui, V.W.3
  • 18
    • 18644367044 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells
    • Thomas SM, Grandis JR, Wentzel AL, Gooding WE, Lui VW and Siegfried JM: Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells. Neoplasia 7: 426-431, 2005.
    • (2005) Neoplasia , vol.7 , pp. 426-431
    • Thomas, S.M.1    Grandis, J.R.2    Wentzel, A.L.3    Gooding, W.E.4    Lui, V.W.5    Siegfried, J.M.6
  • 19
    • 0024508129 scopus 로고
    • Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours
    • Seglen PO, Skomedal H, Saeter G, Schwarze PE and Nesland JM: Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours. Carcinogenesis 10: 21-25, 1989. (Pubitemid 19032078)
    • (1989) Carcinogenesis , vol.10 , Issue.1 , pp. 21-25
    • Seglen, P.O.1    Skomedal, H.2    Saeter, G.3    Schwarze, P.E.4    Nesland, J.M.5
  • 20
    • 33745552897 scopus 로고    scopus 로고
    • Dysregulation of growth factor signaling in human hepatocellular carcinoma
    • Breuhahn K, Longerich T and Schirmacher P: Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 25: 3787-3800, 2006.
    • (2006) Oncogene , vol.25 , pp. 3787-3800
    • Breuhahn, K.1    Longerich, T.2    Schirmacher, P.3
  • 21
    • 16644390138 scopus 로고    scopus 로고
    • Overexpression of extracellular signal-regulated protein kinase and its correlation with proliferation in human hepatocellular carcinoma
    • Tsuboi Y, Ichida T, Sugitani S, et al: Overexpression of extracellular signal-regulated protein kinase and its correlation with proliferation in human hepatocellular carcinoma. Liver Int 24: 432-436, 2004.
    • (2004) Liver Int , vol.24 , pp. 432-436
    • Tsuboi, Y.1    Ichida, T.2    Sugitani, S.3
  • 22
    • 36549013178 scopus 로고    scopus 로고
    • Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection
    • Schmitz KJ, Wohlschlaeger J, Lang H, et al: Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J Hepatol 48: 83-90, 2008.
    • (2008) J Hepatol , vol.48 , pp. 83-90
    • Schmitz, K.J.1    Wohlschlaeger, J.2    Lang, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.