Immunoglobulin G-dependent changes in basophil allergen threshold sensitivity during birch pollen immunotherapy

Clinical and Experimental Allergy

Volumn 40, Issue 8, 2010, Pages 1186-1193

  Lalek, N ^a   Kosnik, M ^a   Silar, M ^a   Korosec, P ^a  

^a UNIVERSITY CLINIC OF RESPIRATORY AND ALLERGIC DISEASES   (Slovenia)

Author keywords

basophil allergen threshold sensitivity; birch pollen subcutaneous immunotherapy; CD63; IgG antibodies

Indexed keywords

ALLERGEN; CD63 ANTIGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G4; POLLEN ANTIGEN;

ADOLESCENT; ADULT; ALLERGIC RHINITIS; ARTICLE; BASOPHIL; BIRCH; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOTHERAPY; MALE; OPEN STUDY; POLLEN; PRIORITY JOURNAL; SYMPTOM; TREATMENT DURATION; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; ALLERGENS; BASOPHILS; BETULA; CELL SEPARATION; DESENSITIZATION, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; RHINITIS, ALLERGIC, SEASONAL; YOUNG ADULT;

EID: 77954358206     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2010.03524.x     Document Type: Article

References (31)

1. Cooke RA, Barnard JH, Hebald S, Stull A. Serological evidence of immunity with coexisting sensitisation in type of human allergy (hay fever). J Exp Med 1935 62 : 733 750.
2. Ball T, Sperr WR, Valent P et al. Induction of antibody responses to new B cell epitopes indicates vaccination character of allergen immunotherapy. Eur J Immunol 1999 29 : 2026 36.
3. Mothes N, Heinzkill M, Drachenberg KJ et al. Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted IgE production and inhibition of basophil histamine release by therapy-induced blocking antibodies. Clin Exp Allergy 2003 33 : 1 11.
4. Bousquet J, Khaltaev N, Cruz AA et al. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the world health organization, GA(2)LEN and AllerGen). Allergy 2008 63 (Suppl. 86) : 8 160.
5. Bousquet J, Lockey RF, Malling HJ. WHO position paper: allergen immunotherapy: therapeutic vaccines for allergic diseases. Allergy 1998 53 (Suppl.) : 1 42. (Pubitemid 28346358)
6. Bødtger U, Poulsen LK, Jacobi HH, Malling HJ. The safety and efficacy of subcutaneous birch pollen immunotherapy - a one-year, randomised, double-blind, placebo-controlled study. Allergy 2002 57 : 297 305.
7. Khinchi MS, Poulsen LK, Carat F, André C, Hansen AB, Malling HJ. Clinical efficacy of sublingual and subcutaneous birch pollen allergen-specific immunotherapy: a randomised, placebo-controlled, double-blind, double-dummy study. Allergy 2004 59 : 45 53. (Pubitemid 38167951)
8. Akdis CA, Blesken T, Akdis M, Wüthrich B, Blaser K. Role of IL-10 in specific immunotherapy. J Clin Invest 1998 102 : 98 106.
9. Akdis M, Akdis CA. Mechanism of allegen-specific immunotherapy. J Allergy Clin Immunol 2007 119 : 780 9.
10. Wanich N, Nowak-Wegrzyn A, Sampson HA, Schreffler WG. Allergen-specific basophil suppression associated with clinical tolerance in patients with milk allergy. J Allergy Clin Immunol 2009 123 : 789 94.
11. Kroeger KM, Sullivan BM, Locksley RM. IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. J Leukoc Biol 2009 86 : 769 78.
12. Konik M, ilar M, Bajrovi N, Mui E, Koroec P. High sensitivity of basophils predicts side-effects in venom immunotherapy. Allergy 2005 60 : 1401 6.
13. Nopp A, Johansson SG, Ankerst J et al. Basophil allergen threshold sensitivity: a useful approach to anti-IgE treatment efficacy evaluation. Allergy 2006 61 : 298 302.
14. Johansson SGO, Nopp A, van Hage M et al. Passive sensitization by blood transfusion. Allergy 2005 60 : 1192 9.
15. Ebo DG, Hagendorens MM, Schuerwegh AJ et al. Flow-assisted quantification of in vitro activated basophils in the diagnosis of wasp venom allergy and follow-up of wasp venom immunotherapy. Cytometry B Clin Cytom 2007 72 : 196 203.
16. Peternelj A, Silar M, Erzen R, Kosnik M, Korosec P. Basophil sensitivity in patients not responding to venom immunotherapy. Int Arch Allergy Immunol 2008 146 : 248 54.
17. Nopp A, Cardell LO, Johansson SG, Oman H. CD-sens: a biological measure of immunological changes stimulated by ASIT. Allergy 2009 64 : 811 4.
18. Jones SM, Pons L, Roberts JL et al. Clinical efficacy and immune regulation with peanut oral immunotherapy. J Allergy Clin Immunol 2009 124 : 292 300.
19. Horak F, Zieglmayer P, Zieglmayer R et al. Early on set of action of a 5-grass-pollen 300-IR sublingual immunotherapy tablet evaluated in an allergen challenge chamber. J Allergy Clin Immunol 2009 124 : 471 7.
20. MacGlashan DW Jr. Releasability of human basophils: cellular sensitivity and maximal histamine release are independent variables. J Allergy Clin Immunol 1993 91 : 605 15.
21. Korosec P, Erzen R, Silar M, Bajrovic N, Kopac P, Kosnik M. Basophil responsiveness in patients with insect sting allergies and negative venom-specific immunoglobulin E and skin prick test results. Clin Exp Allergy 2009 39 : 1730 7.
22. Jakobsen CG, Bodtger U, Poulsen LK, Roggen EL. Vaccination for birch pollen allergy: comparison of the affinities of specific immunoglobulins E, G1 and G4 measured by surface plasmon resonance. Clin Exp Allergy 2005 35 : 193 8.
23. Reisinger J, Horak F, Pauli G et al. Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity. J Allergy Clin Immunol 2005 116 : 347 54.
24. Wachholz PA, Kristensen Soni N, Till SJ, Durham SR. Inhibition of allergen-IgE binding to B cells by antibodies after grass pollen immunotherapy. J Allergy Clin Immunol 2003 112 : 915 22.
25. Djurup R, Malling HJ. High IgG4 antibody level is associated with failure of immunotherapy with inhalant allergens. Clin Allergy 1987 17 : 459 68.
26. Kepley CL, Cambier JC, Morel PA et al. Negative regulation of FcepsilonRI signaling by FcgammaRII costimulation in human blood basophils. J Allergy Clin Immunol 2000 106 : 337 48.
27. Wigginton SJ, Furtado PB, Armour KL et al. An immunoglobulin E-reactive chimeric human immunoglobulin G1 anti-idiotype inhibits basophil degranulation through cross-linking of FcepsilonRI with FcgammaRIIb. Clin Exp Allergy 2008 38 : 313 9.
28. Kepley CL, Taghavi S, Mackay G et al. Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes. J Biol Chem 2004 279 : 35139 49.
29. Ejrnaes AM, Svenson M, Lund G, Larsen JN, Jacobi H. Inhibition of rBet v 1-induced basophil histamine release with specific immunotherapy-induced serum immunoglobulin G: no evidence that FcgammaRIIB signalling is important. Clin Exp Allergy 2006 36 : 273 82.
30. Varga EM, Francis JN, Zach MS, Klunker S, Aberer W, Durham SR. Time course of serum inhibitory activity for facilitated allergen-IgE binding during bee venom immunotherapy in children. Clin Exp Allergy 2009 39 : 1353 7.
31. Vonakis BM, Gibbons S Jr., Sora R, Langdon JM, MacDonald SM. Src homology 2 domain-containing inositol 5′ phosphatase is negatively associated with histamine release to human recombinant histamine-releasing factor in human basophils. J Allergy Clin Immunol 2001 108 : 822 31.