Implementation of the INTERCEPT blood system for platelets into routine blood bank manufacturing procedures: Evaluation of apheresis platelets

Vox Sanguinis

Volumn 86, Issue 4, 2004, Pages 239-245

  Janetzko, K ^a   Lin, L ^b   Eichler, H ^a   Mayaudon, V ^c   Flament, J ^c   Kluter H ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b CERUS CORPORATION   (United States)

^c Baxter R and D Europe   (Belgium)

Author keywords

Amotosalen; Pathogen inactivation; Photochemical treatment; Platelet concentrates; S 59; UVA

Indexed keywords

GLUCOSE; LACTATE DEHYDROGENASE; LACTIC ACID; PADGEM PROTEIN; THROMBOCYTE CONCENTRATE;

APHERESIS; ARTICLE; BLOOD BANK; BLOOD GAS ANALYSIS; BLOOD STORAGE; CARBON DIOXIDE TENSION; GLUCOSE BLOOD LEVEL; GLUCOSE INTAKE; GOOD MANUFACTURING PRACTICE; HUMAN; LACTATE BLOOD LEVEL; LACTATE DEHYDROGENASE BLOOD LEVEL; OXYGEN TENSION; PH; PHOTOCHEMICAL EFFICIENCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION; ULTRAVIOLET A RADIATION; VIRUS INACTIVATION;

ADSORPTION; ANIMALS; BACTERIA; BLOOD BANKS; BLOOD GLUCOSE; BLOOD PLATELETS; BLOOD PRESERVATION; BLOOD-BORNE PATHOGENS; CARBON DIOXIDE; CROSS-LINKING REAGENTS; HUMANS; LACTATES; LEUKOCYTES; OSMOTIC PRESSURE; OXYGEN; PHOTOCHEMISTRY; PLASMA; PLATELET FUNCTION TESTS; PLATELET TRANSFUSION; PLATELETPHERESIS; PROTOZOA; PSORALENS; ULTRAVIOLET RAYS; VIRUS INACTIVATION;

EID: 3142592149     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0042-9007.2004.00419.x     Document Type: Article

References (19)

1. Council of Europe Expert Committee on Blood Transfusion: Pathogen inactivation of labile blood products. Transfus Med 2001; 11:149-175
2. Klüter H: The struggle for safer blood: pathogen-inactivation of cellular blood preparations. Blood Ther Med 2002; 2:42-47
3. Corash L: Inactivation of infectious pathogens in labile blood components: meeting the challenge. Transfus Clin Biol 2001; 8:138-145
4. Goodrich RP: The use of riboflavin for the inactivation of pathogens in blood products. Vox Sang 2000; 78(Suppl 2):211-215
5. Perez P, Sallmi R, Follea G, Schimt JL, de Barbeyrac B, Sudre P, Salamon R: Determinants of transfusion-associated bacterial contamination: results of the French Bacthem Case-Control study. Transfusion 2001; 41:862-872
6. Bjachman MA, Ali Am Richardson HL: Bacterial contamination of cellular blood components. Vox Sang 1994; 67(Suppl 3):25-33
7. Lin L, Cook DN, Wiesehahn GP, Alfonso R, Behrmann B, Cimino GD, Corten L, Damonte PB, Dikeman R, Dupuis K, Fang YM, Hanson CV, Hearst JE, Lin CY, Metchette K, Nerio AT, Pu JT, Reames AA, Rheinschmidt M, Tessman J, Isaacs ST, Wollowitz S, Corash L: Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light. Transfusion 1997; 37:423-435
8. Lin L, Alfonso R, Behrman B, Corten L, Damonte PB, Dikeman R, Dupuis K, Hei D, Lin CY, Londe HF, Metchette K, Phan T, Reames AA, Rheinschmidt M, Savoor A, Tessmann J, Corash L: Photochemical treatment of platelet concentrates with novel psoralen and UVA to enhance the safety of platelet transfusions. Infus Ther Transfus Med 1998; 25:39-48
9. Van Rhenen DJ, Vermeij J, Mayaudon V, Hind C, Lin L, Corash L: Functional characteristics of S-59 photochemically treated platelet concentrates derived from buffy coats. Vox Sang 2000; 79:206-214
10. Janetzko K, Klinger M, Mayaudon V, Lin L, Eichler H, Klüter H: Storage characteristics of split double-dose platelet concentrates derived from apheresis and treated with amotosalen hydrochloride and UVA light for pathogen inactivation. Infus Ther Transfus Med 2002; 29:193-198
11. Holme S, Moroff G, Murphy S: A multi-laboratory evaluation of in vitro platelet assays: the tests for extent of shape change and response to hypotonic shock. Transfusion 1998; 38:31-40
12. Council of Europe Publishing: Guide to the Preparation, Use and Quality Assurance of Blood Components, edn 8. Recommendation No R (95) 15. Strasbourg Cedex, Council of Europe Publishing, 2003
13. Perrotta PL, Baril L, Tead C, Chapman J, Dincecco D, Buchholz DH, Snyder EL: Effects of methylene blue-treated plasma on red cells and stored platelet concentrates. Transfusion 1999; 39:63-69
14. Koerner K, Sahlmen P, Zimmermann B, Cardoso M, Kubanek B: In vitro platelet function during storage in three different additive solutions. Vox Sang 1994; 67:154-159
15. Moroff G, Holme MH, Debay MH, Sawyer S, Heaton WAL, Law P: Storage of pools six and eight platelet concentrates. Transfusion 1993; 33:374-378
16. Zeiler T, Wilber U, Schulzki T, Kretschmer V: In vitro properties of platelet concentrates. Infus Ther Transfus Med 2001; 28:9-14
17. Klinger M, Josch M, Klüter H: Platelets stored in a glucose-free additive solution or in autologous plasma - an utrastructural and morphometric study. Vox Sang 1996; 71:13-20
18. Holme S, Heaton WA, Moroff G: Evaluation of platelet concentrates stored for 5 days with reduced plasma volume. Transfusion 1994; 34:39-43
19. Ciaravino V, McCullough T, Dayan AD: Pharmacokinetic and toxicology assessment of INTERCEPT (S-59 and UVA treated) platelets. Human Exp Toxicol 2001; 20:533-550