Extraction of standardized archetyped data from Electronic Health Record systems based on the Entity-Attribute-Value Model

International Journal of Medical Informatics

Volumn 79, Issue 8, 2010, Pages 585-597

  Duftschmid, Georg ^a   Wrba, Thomas ^a   Rinner, Christoph ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Computerized; Medical Records; Medical Records Systems; Models; Reference Standards; Theoretical

Indexed keywords

CLINICAL RESEARCH; COMPUTERIZED MEDICAL RECORDS; DATA AND METADATA; DATA EXTRACTION; DATA MODELS; ELECTRONIC HEALTH RECORD; ELECTRONIC HEALTH RECORD SYSTEMS; MEDICAL RECORD; PRACTICAL IMPLEMENTATION; REFERENCE MODELS; REFERENCE STANDARD; RESEARCH ISSUES; SEMANTIC MAPPING; SYSTEMS MODELS; TEST DATA; UNIVERSITY OF VIENNA; VALUE MODEL; VALUE-BASED; XML TECHNOLOGY;

MARKUP LANGUAGES; MEDICAL COMPUTING; METADATA; RECORDS MANAGEMENT; RESEARCH; SEMANTICS; STANDARDS; XML;

HEALTH;

ARTICLE; CLINICAL RESEARCH; COMPUTER INTERFACE; DATA EXTRACTION; ELECTRONIC MEDICAL RECORD; INFORMATION TECHNOLOGY; MEDICAL INFORMATION SYSTEM; PRIORITY JOURNAL; SEMANTICS; THEORETICAL MODEL; UNIVERSITY; COMPUTER LANGUAGE;

ELECTRONIC HEALTH RECORDS; MODELS, THEORETICAL; PROGRAMMING LANGUAGES;

EID: 77954316307     PISSN: 13865056     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijmedinf.2010.04.007     Document Type: Article

References (43)

1. Commission of the European Communities, e-Health-Making Healthcare Better for European Citizens: An Action Plan for a European e-Health Area, 2004, Available at: (accessed January 26, 2010). http://ec.europa.eu/information_society/doc/qualif/health/COM_2004_0356_F_EN_ACTE.pdf.
2. Dorda W., Duftschmid G., Gerhold L., Gall W., Gambal J. Austria's Path toward nationwide Electronic Health Record's. Methods Inf. Med. 2008, 47(2):117-123.
3. European Commission, eHealth Priorities and Strategies in European Countries, 2007, Available at: (accessed January 26, 2010). http://ec.europa.eu/information_society/activities/health/docs/policy/ehealth-era-full-report.pdf.
4. European Commission, European Patients Smart Open Services (epSOS), 2009, Available at: (accessed January 25, 2010). http://www.epsos.eu/.
5. P. Gibbons, N. Arzt, S. Burke-Beebe, C. Chute, G. Dickinson, T. Flewelling et al. (Health Level Seven EHR Interoperability Work Group). Coming to Terms: Scoping Interoperability for Health Care, 2007, Available at: (accessed January 26, 2010). http://www.hln.com/assets/pdf/Coming-to-Terms-February-2007.pdf.
6. European Committee for Standardization, EN 13606 Electronic Healthcare Record Communication, 2007, Available at: (accessed January 25, 2010). http://www.cen.eu/.
7. International Organization for Standardization, ISO 13606 Electronic Health Record Communication, 2008, Available at: (accessed January 25, 2010). http://www.iso.org/.
8. T. Beale, Archetypes, Constraint-based Domain Models for Futureproof Information Systems, 2001, Available at: (accessed January 25, 2010). http://www.openehr.org/publications/archetypes/archetypes_beale_web_2000.pdf.
9. Kalra D., Blobel B.G. Semantic interoperability of EHR systems. Stud. Health Technol. Inform. 2007, 127:231-245.
10. Hoy D., Hardiker N.R., McNicoll I.T., Westwell P. A feasibility study on clinical templates for the National Health Service in Scotland. Stud. Health Technol. Inform. 2007, 129(Pt 1):770-774.
11. Hoy D., Hardiker N.R., McNicoll I.T., Westwell P., Bryans A. Collaborative development of clinical templates as a national resource. Int. J. Med. Inform. 2009, 78(Supplement 1):95-100.
12. National Health Service (NHS)-Connecting for Health (CFH), The NHS Clinical Models Project, 2008, Available at: (accessed January 25, 2010). http://www.ehr.chime.ucl.ac.uk/display/nhsmodels/.
13. International Organization for Standardization, ISO/TR 20514:2005 Health Informatics - Electronic Health Record - Definition, Scope and Context, 2005, Available at: (accessed January 25, 2010). http://www.iso.org/iso/iso_catalogue/catalogue_tc/catalogue_detail.htm%3Fcsnumber=39525.
14. Garde S., Knaup P., Hovenga E., Heard S. Towards semantic interoperability for electronic health records. Methods Inf. Med. 2007, 46(3):332-343.
15. Chen R., Klein G.O., Sundvall E., Karlsson D., Ahlfeldt H. Archetype-based conversion of EHR content models: pilot experience with a regional EHR system. BMC Med. Inform. Decis. Mak. 2009, 9:33.
16. Beck P., Truskaller T., Rakovac I., Cadonna B., Pieber T.R. On-the-fly form generation and on-line metadata configuration-a clinical data management Web infrastructure in Java. Stud. Health Technol. Inform. 2006, 124:271-276.
17. Brandt C.A., Deshpande A.M., Lu C., Ananth G., Sun K., Gadagkar R., et al. TrialDB: a web-based clinical study data management system. AMIA Annu. Symp. Proc. 2003, p. 794.
18. Nadkarni P.M., Brandt C., Frawley S., Sayward F.G., Einbinder R., Zelterman D., et al. Managing attribute-value clinical trials data using the ACT/DB client-server database system. J. Am. Med. Inform. Assoc. 1998, 5(2):139-151.
19. Anhoj J. Generic design of Web-based clinical databases. J. Med. Internet Res. 2003, 5(4):e27.
20. Friedman C., Hripcsak G., Johnson S., Cimino J., Clayton P. A generalized relational schema for an integrated clinical patient database. Proc. Annu. Symp. Comp. Appl. Med. Care, November 1990 1990, 340-344. IEEE Computer Society Press, Los Alamitos, CA.
21. Dinu V., Nadkarni P. Guidelines for the effective use of entity-attribute-value modeling for biomedical databases. Int. J. Med. Inform. 2007, 76(11-12):769-779.
22. Dorda W., Wrba T., Duftschmid G., Sachs P., Gall W., Rehnelt C., et al. ArchiMed: a medical information and retrieval system. Methods Inf. Med. 1999, 38(1):16-24.
23. Duftschmid G., Gall W., Eigenbauer E., Dorda W. Management of data from clinical trials using the ArchiMed system. Med. Inform. Internet Med. 2002, 27(2):85-98.
24. Lopez D.M., Blobel B. Enhanced semantic interoperability by profiling health informatics standards. Methods Inf. Med. 2009, 48(2):170-177.
25. Maldonado J.A., Moner D., Boscá D., Fernández-Breis J.T., Angulo C., Robles M. LinkEHR-Ed: a multi-reference model archetype editor based on formal semantics. Int. J. Med. Inform. 2009, 78(8):559-570.
26. Maldonado J.A., Moner D., Tomas D., Angulo C., Robles M., Fernandez J.T. Framework for clinical data standardization based on archetypes. Medinfo 2007, 12(Pt 1):454-458.
27. Ronald Bourret, XML-DBMS-Middleware for Transferring Data between XML Documents and Relational Databases, 2009, Available at: (accessed January 25, 2010). http://www.rpbourret.com/xmldbms/.
28. Nadkarni P.M., Marenco L., Chen R., Skoufos E., Shepherd G., Miller P. Organization of heterogeneous scientific data using the EAV/CR representation. J. Am. Med. Inform. Assoc. 1999, 6(6):478-493.
29. Rinner C., Janzek-Hawlat S., Sibinovic S., Duftschmid G. Semantic validation of standard based electronic health record documents with W3C XML Schema. Methods Inf. Med. 2010, 49(3):271-280.
30. Janzek-Hawlat S., Kuttin O., Sibinovic S., Duftschmid G. Automatisierte Generierung von XML-Schemata aus EN/ISO 13606 Archetypen. eHealth2009 & eHealth Benchmarking 2009-Medical Informatics meets eHealth 2009, 69-75. (German).
31. Z. Tun, L.J. Bird, A. Goodchild (CRC for Enterprise Distributed Systems: University of Queensland), Validating Electronic Health Records Using Archetypes and XML, 2002, Available at: (accessed January 25, 2010). http://citeseer.ist.psu.edu/tun02validating.html.
32. Duftschmid G., Wrba T. A tool for the design of clinical forms supporting end-user integration. Med. Inform. Internet Med. 2004, 29(1):29-41.
33. Biomedical Informatics Group at the Technical University of Valencia, The LinkEHR Project, 2008, Available at: (accessed January 25, 2010). http://www.linkehr.com/.
34. Martinez I., Fernandez J., Galarraga M., Serrano L., de Toledo P., Escayola J., et al. Implementation experience of a patient monitoring solution based on end-to-end standards. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2007 2007, 6426-6429.
35. Martinez-Costa C., Menarguez-Tortosa M., Fernandez-Breis J.T., Maldonado J.A. A model-driven approach for representing clinical archetypes for Semantic Web environments. J. Biomed. Inform. 2009, 42(1):150-164.
36. Smith K., Kalra D. Electronic health records in complementary and alternative medicine. Int. J. Med. Inform. 2008, 77(9):576-588.
37. Kabak Y., Dogac A., Köse I., Akpinar N., Gürel M., Arslan Y., et al. The use of HL7 CDA in the National Health Information System (NHIS) of Turkey. 9th International HL7 Interoperability Conference (IHIC) 2008 2008, 49-55.
38. Dolin R.H., Alschuler L., Boyer S., Beebe C., Beilen F.M., Biron P.V., et al. HL7 clinical document architecture, Release 2. J. Am. Med. Inform. Assoc. 2006, 13(1):30-39.
39. Bird L., Goodchild A., Tun Z. Experiences with a two-level modelling approach to electronic health records. J. Res. Prac. Inf. Tech. 2003, 35(2):121-138.
40. Munoz A., Somolinos R., Pascual M., Fragua J.A., Gonzalez M.A., Monteagudo J.L., et al. Proof-of-concept design and development of an EN13606-based electronic health care record service. J. Am. Med. Inform. Assoc. 2007, 14(1):118-129.
41. Integrating the Healthcare Enterprise (IHE), IT Infrastructure Technical Framework, vol. 1 (ITI TF-1, chapter 10), vol. 2 (ITI TF-2, chapter 3.14 and Appendix L), 2007, Available at: (accessed January 25, 2010). http://www.ihe.net/technical_framework/index.cfm%23IT.
42. T. Beale, S. Heard, D. Kalra, D. Lloyd, The openEHR Reference Model-Common Information Model, 2008, Available at: (accessed January 25, 2010). http://www.openehr.org/releases/1.0.2/architecture/rm/common_im.pdf.
43. European Committee for Standardization, CEN/TS 14796 Health informatics-Data types, 2004, Available at: (accessed January 25, 2010). http://www.cen.eu/.