Synthesis and antiproliferative evaluation of 5-oxo and 5-thio derivatives of 1,4-diaryl tetrazoles

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 13, 2010, Pages 3920-3924

  Gundugola, Aditya S ^a   Chandra, Kusum Lata ^a   Perchellet, Elisabeth M ^a   Waters, Andrew M ^a   Perchellet, Jean Pierre H ^a   Rayat, Sundeep ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Antiproliferative activity; Copper catalyzed N arylation; Lawesson's reagent; Tetrazol 5 one; Tetrazole 5 thione

Indexed keywords

1 (2 ETHYNYLPHENYL) 4 PHENYL TETRAZOLE 5 THIONE; 1,4 DIPHENYL 1H TETRAZOLE 5 (4H)THIONE; BORONIC ACID DERIVATIVE; COPPER; KI 67 ANTIGEN; LEWIS ACID; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; ARYLATION; BREAST CANCER; CANCER CELL; CANCER GROWTH; CELL PROLIFERATION; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; IN VITRO STUDY; LEUKEMIA L 1210; LITHIATION; MOUSE; NONHUMAN; PROTON TRANSPORT; SONOGASHIRA REACTION; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KI-67 ANTIGEN; MICE; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLES;

EID: 77954309651     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.05.012     Document Type: Article

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