Preparation and characterization of 5-fluorouracil loaded chitosan microspheres by a two-step solidification method

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 7, 2010, Pages 891-895

  Sun, Yi ^a   Gu, Lei ^a   Gao, Yuan ^a   Gao, Feng ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

5 fluorouracil; Chitosan microsphere; Glutaraldehyde; Tripolyphosphate; Two step solidification

Indexed keywords

CHITOSAN; CROSS LINKING REAGENT; FLUOROURACIL; GLUTARALDEHYDE; MACROGOL 6000; MICROSPHERE; POLYSORBATE 80; SORBITAN OLEATE; TRIPOLYPHOSPHATE; ANTINEOPLASTIC ANTIMETABOLITE; DELAYED RELEASE FORMULATION; POLYPHOSPHATE; TRIPHOSPHORIC ACID;

ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; EMULSION; ENCAPSULATION; IN VITRO STUDY; MORPHOLOGY; PHYSICAL CHEMISTRY; SOLID; SURFACE PROPERTY; TECHNIQUE; CHEMISTRY; DELAYED RELEASE FORMULATION; INFRARED SPECTROSCOPY; PH; PHARMACEUTICS; PROCEDURES;

ANTIMETABOLITES, ANTINEOPLASTIC; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; FLUOROURACIL; GLUTARAL; HYDROGEN-ION CONCENTRATION; MICROSPHERES; POLYPHOSPHATES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL;

EID: 77954303636     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.891     Document Type: Article

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