Ipsilateral breast tumour recurrence (IBTR) dynamics in breast conserving treatments with or without radiotherapy

International Journal of Radiation Biology

Volumn 86, Issue 7, 2010, Pages 542-547

  Demicheli, Romano ^a   Ardoino, Ilaria ^b   Boracchi, Patrizia ^c   Lozza, Laura ^a   Biganzoli, Elia ^c  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b Department of Medical Statistics and Biometry ^*  (United Kingdom)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

breast cancer; breast conserving surgery; IBTR dynamics; post operative RT; tumour dormancy

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DISTANT METASTASIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENCE RISK; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT; TUMOR VOLUME;

ADULT; AGE FACTORS; AGED; BREAST NEOPLASMS; HUMANS; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RADIOTHERAPY, ADJUVANT; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME;

EID: 77954281769     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553001003734550     Document Type: Article

References (30)

1. Barcellos-Hof MH, Park C, Wright EG. 2005. Radiation and the microenvironment-tumorigenesis and therapy. Nature Review Cancer 5:867-875.
2. Belletti B, Vaidya JS, D'Andrea S, Entschladen F, Roncadin M, Lovat F, Berton S, Perin T, Candiani E, Reccanello S, Veronesi A, Canzonieri V, Trovo MG, Zaenker KS, Colombatti A, Baldassarre G, Massarut S. 2008. Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding. Clinical Cancer Research 14:1325-1332.
3. Boracchi P, Biganzoli E, Marubini E. 2003. Joint modelling of cause-specific hazard functions with cubic splines: An application to a large series of breast cancer patients. Computational Statistics & Data Analysis 42:243-262.
4. Demicheli R, Terenziani M, Valagussa P, Moliterni A, Zambetti, Bonadonna G. 1994. Local recurrences following mastectomy: Support for the concept of tumour dormancy. Journal of National Cancer Institute 86:45-48.
5. Demicheli R, Abbattista A, Miceli R Valagussa P, Bonadonna G. 1996. Time distribution of the recurrence risk for breast cancer patients undergoing mastectomy: Further support about the concept of tumour dormancy. Breast Cancer Research and Treatment 41:177-185.
6. Demicheli R, Retsky MW, Swartzendruber DE, Bonadonna G. 1997. Proposal for a new model of breast cancer metastatic development. Annals of Oncology 8:1075-1080.
7. Demicheli R, Retsky MW, Hrushesky WJM, Baum M. 2007. Tumor dormancy and surgery-driven dormancy interruption in breast cancer: Learning from failures. Nature Clinical Practice Oncology 4:699-710.
8. Demicheli R, Retsky MW, Hrushesky WJM, Baum M, Gukas ID. 2008. The effects of surgery on tumour growth: A century of investigations. Annals of Oncology 19:1821-1828
9. Early Breast Cancer Trialists' Collaborative Group. 2005. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrences and 15-year survival: An overview of the randomized trials. The Lancet 366:2087-2106.
10. Fisher B, Anderson ER, Redmond C, Wickerham DL, Wolmark N, Mamounas EP, Deutsck M, Margolese R. 1991. Significance of ipsilateral breast tumour recurrence after lumpect-omy. The Lancet 338:327331.
11. Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, Jeong JH, Wolmark N. 2002. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. New England Journal of Medicine 17:1233-1241.
12. Fisher ER, Gregorio R, Redmond C, Vellios F, Sommers SC, Fisher B. 1975. Pathologic findings from the National Surgical Adjuvant Breast Project (Protocol No 4). I. Observations concerning the multicentricity of mammary cancer. Cancer 35:247-254.
13. Formenti FC, Demaria S. 2008. Local control by radiotherapy: Is that all there is? Breast Cancer Research 10:215.
14. Haveman J, Rodermond H, vanBree C, Wondergem J, Franken NAP. 2007. Residual late radiation damage in mouse stromal tissue assessed by tumor bed effect. Journal of Radiation Research 48:107-112.
15. Holland R, Veling SHJ, Mravunac M, Hendriks JHCL. 1985. Histologic mulifocality of Tis, T1-2 breast carcinomas. Implications for clinical trials of breast-conserving surgery. Cancer 56:979-990.
16. Jatoi I, Proschan MA. 2005. Randomized trials of breast conserving-therapy versus mastectomy for primary breast cancer. A pooled analysis of updated results. American Journal of Clinical Oncology 28:289-294.
17. Kozin SV, Boucher Y, Hicklin DJ, Bohlen P, Jain RK, Suit HD. 2001. Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Research 61:39-44.
18. Marubini E, Valsecchi MG. 1995. Analysing survival data from clinical trials and observational studies, Statistics in practice. Chichester, UK: John Wiley & Sons.
19. Ramlau-Hansen H. 1983. Smoothing counting process intensities by means of Kernel functions. Annals of Statistics 11:453-466.
20. Retsky MW, Demicheli R, Swartzendruber DE, Bame PD, Wardwell RH, Bonadonna G, Speer JF, Valagussa P. 1997. Computer simulation of a breast cancer metastasis model. Breast Cancer Research and Treatment 45:193-202. (Pubitemid 27399967)
21. Retsky MV, Demicheli R, Hrushesky WJM, Baum M, Gukas ID. 2008. Dormancy and surgery-driven escape from dormancy help explain some clinical features of breast cancer. Acta Pathologica Microbiologica et Immunologica Scandinavica 116:730-741.
22. Rosen PP, Fracchia AA, Urban JA, Schottenfeld D, Robbins GF. 1975. 'Residual' mammary carcinoma following simulated partial mastectomy. Cancer 35:739-747.
23. Saeki Y, Shimazaki S, Urano M. 1971. Radiation effect on the vascularization of a C3H mammary carcinoma. Microangio-graphic studies of the tumour in preirradiated tissue and of the recurrent tumour. Radiology 101:175-180.
24. Summers WC, Clifton KH, Vermund H. 1964. X-irradiation of the tumour bed. I. A study of the indirect actions of radiation on transplantable tumours. Radiology 82:691-703.
25. Tagliabue E, Agresti R, Carcangiu ML, Ghirelli C, Morelli D, Campiglio M, Martel M, Giovanazzi R, Greco M, Balsari A, Menard S. 2003. Role of HER2 in wound-induced breast carcinoma proliferation. The Lancet 362:527-533. (Pubitemid 36980657)
26. Vaidya JS, Vyas JJ, Chinoy RF, Merchant N, Sharma OP, Mittra I. 1996. Multicentricity of breast cancer: Whole-organ analysis and clinical implications. British Journal of Cancer 74:820-824.
27. Veronesi U, Volterrani F, Luini A, Saccozzi R, Del Vecchio M, Zucali R, Galimberti V, Rasponi A, Di Re E, Squicciarini P. 1990. Quadrantectomy versus lumpectomy for small size breast cancer. European Journal of Cancer 26:671-673.
28. Veronesi U, Marubini E, Mariani L, Galimberti V, Luini A, Veronesi P, Salvadori B, Zucali R. 2001. Radiotherapy after breast-conserving surgery in small breast carcinoma: Long-term results of a randomized trial. Annals of Oncology 12:997-1003.
29. Zips D, Eicheler W, Geyer P, Hessel F, Dörfler A, Thames HD, Haberey M, Baumann M. 2005a. Enhanced susceptibility of irradiated tumor vessels to vascular endothelial growth factor receptor tyrosine kinase inhibition. Cancer Research 65:5374-5379.
30. Zips D, Hessel F, Krause M, Schiefer Y, Hoinkis C, Thames HD, Haberey M, Baumann M. 2005b. Impact of adjuvant inhibition of vascular endothelial growth factor receptor tyrosine kinases on tumor growth delay and local tumor control after fractionated irradiation in human squamous cell carcinomas in nude mice. International Journal of Radiation Oncology Biology and Physics 61:908-914.