Water-soluble organic solubilizers for in vitro drug delivery studies with respiratory epithelial cells: Selection based on various toxicity indicators

Drug Delivery

Volumn 17, Issue 6, 2010, Pages 434-442

  MacDonald, Chris ^a   Lyzenga, Wendy ^a   Shao, Di ^a   Agu, Remigius U ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Calu 3 cells; Drug delivery; Solubility enhancing excipients; Solubilizers; Toxicity

Indexed keywords

1 METHYL 2 PYRROLIDINONE; ACTIN; AROMATIC HYDROCARBON; CREMOPHOR; DIMETHYL SULFOXIDE; LACTATE DEHYDROGENASE; MACROGOL 400; N,N DIMETHYLACETAMIDE; EXCIPIENT; FLUORESCENT DYE; PHARMACOLOGICAL BIOMARKER; SOLVENT;

ARTICLE; CELL LINE; CELL VIABILITY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ELECTRIC RESISTANCE; EPITHELIUM CELL; IN VITRO STUDY; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; CELL MEMBRANE; CELL SURVIVAL; CHEMISTRY; CYTOSKELETON; DRUG EFFECTS; DRUG SCREENING; HUMAN; IMPEDANCE; OSMOLARITY; PERMEABILITY; PROCEDURES; RESPIRATORY TRACT MUCOSA; SOLUBILITY; TIGHT JUNCTION; TOXICITY; ULTRASTRUCTURE;

BIOMARKERS, PHARMACOLOGICAL; CELL LINE; CELL MEMBRANE; CELL SURVIVAL; CYTOSKELETON; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; ELECTRIC IMPEDANCE; EXCIPIENTS; FLUORESCENT DYES; HUMANS; OSMOLAR CONCENTRATION; PERMEABILITY; RESPIRATORY MUCOSA; SOLUBILITY; SOLVENTS; TIGHT JUNCTIONS;

EID: 77954265937     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717541003777548     Document Type: Article

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