Synthesis and bioactivity of (±)-tetrahydrohaliclonacyclamine A

Tetrahedron

Volumn 66, Issue 26, 2010, Pages 4805-4810

  Smith, Brian J ^a   Qu, Tao ^a,b   Mulder, Matthew ^a   Noetzel, Meredith J ^a   Lindsley, Craig W ^a   Sulikowski, Gary A ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Marine alkaloid; Muscarinic M1 antagonist; Ring closing metathesis; Stereoselective hydrogenation; Stille cross coupling

Indexed keywords

ALKALOID DERIVATIVE; G PROTEIN COUPLED RECEPTOR; ION CHANNEL; MACROCYCLIC COMPOUND; MUSCARINIC M1 RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE; TETRAHYDROHALICLONACYCLAMINE A; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGENATION; PRIORITY JOURNAL; QUANTUM YIELD; REACTION ANALYSIS; RING CLOSING METATHESIS; STEREOCHEMISTRY; STILLE REACTION;

EID: 77954231370     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.03.117     Document Type: Article

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