Estrogen reduces BDNF level, but maintains dopaminergic cell density in the striatum of MPTP mouse model

International Journal of Neuroscience

Volumn 120, Issue 7, 2010, Pages 489-495

  Tripanichkul, Wanida ^a   Gerdprasert, Orapin ^a   Jaroensuppaperch, Em Orn ^a  

^a SRINAKHARINWIROT UNIVERSITY   (Thailand)

Author keywords

17 estradiol; BDNF; Dopaminergic neuron; MPTP; Striatum

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BRAIN DERIVED NEUROTROPHIC FACTOR; ESTRADIOL; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CELL DENSITY; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DRUG EFFECT; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INNERVATION; MALE; MOUSE; NERVE FIBER; NONHUMAN; OPTICAL DENSITY; PRESERVATION; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; AXONS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOPAMINE; DOWN-REGULATION; ESTROGENS; MALE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; PARKINSONIAN DISORDERS; SUBSTANTIA NIGRA; WALLERIAN DEGENERATION;

EID: 77954206062     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.3109/00207451003721892     Document Type: Article

References (25)

1. Batchelor, P. E., Liberatore, G. T., Porritt, M. J., Donnan, G. A., & Howells, D. W. (2000). Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum. The European Journal of Neuroscience, 12(10), 3462-3468.
2. Bedard, A., Cossette, M., Levesque, M., & Parent, A. (2002). Proliferating cells can differentiate into neurons in the striatum of normal adult monkey. Neuroscience Letters, 328(3), 213-216.
3. Bedard, A., Gravel, C., & Parent, A. (2006). Chemical characterization of newly generated neurons in the striatum of adult primates. Experimental Brain Research, 170(4), 501-512.
4. Betarbet, R., Turner, R., Chockkan, V., DeLong, M. R., Allers, K. A., Walters, J., et al. (1997). Dopaminergic neurons intrinsic to the primate striatum. The Journal of Neuroscience, 17(17), 6761-6768.
5. D'Astous, M., Morissette, M., Tanguay, B., Callier, S., & Di Paolo, T. (2003). Dehydroepiandrosterone (DHEA) such as 17betaestradiol prevents MPTP-induced dopamine depletion in mice. Synapse, 47(1), 10-14.
6. Darmopil, S., Muneton-Gomez, V. C., de Ceballos, M. L., Bernson, M., & Moratalla, R. (2008). Tyrosine hydroxylase cells appearing in themouse striatum after dopamine denervation are likely to be projection neurones regulated by L-DOPA. The European Journal of Neuroscience, 27(3), 580-592.
7. DeLong, M. R. (1990). Primate models of movement disorders of basal ganglia origin. Trends in Neurosciences, 13(7), 281-285.
8. Disshon, K. A., Boja, J.W., & Dluzen, D. E. (1998). Inhibition of striatal dopamine transporter activity by 17beta-estradiol. European Journal of Pharmacology, 345(2), 207-211.
9. Dluzen, D. (1997). Estrogen decreases corpus striatal neurotoxicity in response to 6-hydroxydopamine. Brain Research, 767(2), 340-344.
10. Dluzen, D. E. (2000). Neuroprotective effects of estrogen upon the nigrostriatal dopaminergic system. Journal of Neurocytology, 29(5-6), 387-399.
11. Du, X., Stull, N. D., & Iacovitti, L. (1995). Brain-derived neurotrophic factor works coordinately with partner molecules to initiate tyrosine hydroxylase expression in striatal neurons. Brain Research, 680(1-2), 229-233.
12. Franklin, K. B. J., & Paxinos, G. (1997). TheMouse Brain in the Stereotaxic Coordinates. San Diego: Academic Press.
13. Hung, H. C., & Lee, E. H. (1996). The mesolimbic dopaminergic pathway is more resistant than the nigrostriatal dopaminergic pathway to MPTP and MPP+ toxicity: Role of BDNF gene expression. Brain Research. Molecular Brain Research, 41(1-2), 14-26.
14. Leonard, S., Luthman, D., Logel, J., Luthman, J., Antle, C., Freedman, R., et al. (1993). Acidic and basic fibroblast growth factor mRNAs are increased in striatum following MPTPinduced dopamine neurofiber lesion: Assay by quantitative PCR. Brain Research. Molecular Brain Research, 18(4), 275-284.
15. Levivier, M., Przedborski, S., Bencsics, C., & Kang, U. J. (1995). Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. The Journal of Neuroscience, 15(12), 7810-7820.
16. Nakahara, T., Yamamoto, T., Endo, K., & Kayama, H. (2001). Neuronal ectopic expression of tyrosine hydroxylase in the mouse striatum by combined administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 3-nitropropionic acid. Neuroscience, 108(4), 601-610.
17. Porritt, M. J., Batchelor, P. E., Hughes, A. J., Kalnins, R., Donnan, G. A., & Howells, D. W. (2000). New dopaminergic neurons in Parkinson's disease striatum. Lancet, 356(9223), 44-45.
18. Raab, H., Pilgrim, C., & Reisert, I. (1995). Effects of sex and estrogen on tyrosine hydroxylase mRNA in cultured embryonic rat mesencephalon. Brain Research. Molecular Brain Research, 33(1), 157-164.
19. Suzuki, S., Gerhold, L. M., Bottner, M., Rau, S. W., Dela Cruz, C., Yang, E., et al. (2007). Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta. The Journal of Comparative Neurology, 500(6), 1064-1075.
20. Tripanichkul, W., Sripanichkulchai, K., & Finkelstein, D. I. (2006). Estrogen down-regulates glial activation in male mice following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication. Brain Research, 1084(1), 28-37.
21. Tsang, K. L., Ho, S. L., & Lo, S. K. (2000). Estrogen improves motor disability in parkinsonian postmenopausal women with motor fluctuations. Neurology, 54(12), 2292-2298.
22. Vegeto, E., Bonincontro, C., Pollio, G., Sala, A., Viappiani, S., Nardi, F., et al. (2001). Estrogen prevents the lipopolysaccharideinduced inflammatory response in microglia. The Journal of Neuroscience, 21(6), 1809-1818.
23. West, M. J., Ostergaard, K., Andreassen, O. A., & Finsen, B. (1996). Estimation of the number of somatostatin neurons in the striatum: An in situ hybridization study using the optical fractionator method. The Journal of Comparative Neurology, 370(1), 11-22.
24. Zhou, J., Pliego-Rivero, B., Bradford, H. F., & Stern, G. M. (1996). The BDNF content of postnatal and adult rat brain: The effects of 6-hydroxydopamine lesions in adult brain. Brain Research. Developmental Brain Research, 97(2), 297-303.
25. Zhou, J., Shen, Y., Tang, Z., Xu, L., Bradford, H. F., & Yu, Y. (2000). Striatal extracts promote the survival and phenotypic expression of rat fetal dopaminergic neurons in vitro. Neuroscience Letters, 292(1), 5-8.