메뉴 건너뛰기




Volumn 45, Issue 3, 2010, Pages 516-524

Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANDROGEN; FLUTAMIDE;

EID: 77954196465     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2008.01285.x     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 0028347247 scopus 로고
    • Flutamide as a tool to-study the hormonal regulation of the reproductive tract in the golden hamster
    • Balbotin JB. Flutamide as a tool to-study the hormonal regulation of the reproductive tract in the golden hamster. Andrology 1994, 26:27-32.
    • (1994) Andrology , vol.26 , pp. 27-32
    • Balbotin, J.B.1
  • 2
    • 0026356506 scopus 로고
    • Comparative effects of chronic adminisntration of the non-seteroidal antiandrogens flutamide and Casodex on the reprodutive system of the adult male rat
    • Chandolia RK, Weinbauer GF, Simoni M, Behre HM, Nieschlag E. Comparative effects of chronic adminisntration of the non-seteroidal antiandrogens flutamide and Casodex on the reprodutive system of the adult male rat. Acta Endocrinol 1991, 125:547-555.
    • (1991) Acta Endocrinol , vol.125 , pp. 547-555
    • Chandolia, R.K.1    Weinbauer, G.F.2    Simoni, M.3    Behre, H.M.4    Nieschlag, E.5
  • 3
    • 77954205802 scopus 로고    scopus 로고
    • Is cadmium chloride-induced inter-Sertoli tight junction permeability barrier disruption a suitable in vitro model to study the events
    • Chung NP, Cheng CY. Is cadmium chloride-induced inter-Sertoli tight junction permeability barrier disruption a suitable in vitro model to study the events. Endocrinology 2001, 38:195-201.
    • (2001) Endocrinology , vol.38 , pp. 195-201
    • Chung, N.P.1    Cheng, C.Y.2
  • 4
    • 2542458436 scopus 로고    scopus 로고
    • Tissue alterations in the Guinea pig lateral prostate followoing antiandrogen flutamide therapy
    • Cordeiro RS, Scarano WR, Góes RM, Taboga ST. Tissue alterations in the Guinea pig lateral prostate followoing antiandrogen flutamide therapy. Biol Cell 2004, 28:21-30.
    • (2004) Biol Cell , vol.28 , pp. 21-30
    • Cordeiro, R.S.1    Scarano, W.R.2    Góes, R.M.3    Taboga, S.T.4
  • 5
    • 14344262900 scopus 로고    scopus 로고
    • Inhibition of 5-alpha-reductase activity induces stromal remodeling and smooth muscle dedifferentiation in adult gerbil ventral prostate
    • Corradi LS, Góes RM, Carvalho HF, Taboga SR. Inhibition of 5-alpha-reductase activity induces stromal remodeling and smooth muscle dedifferentiation in adult gerbil ventral prostate. Differentiation 2004, 72:198-208.
    • (2004) Differentiation , vol.72 , pp. 198-208
    • Corradi, L.S.1    Góes, R.M.2    Carvalho, H.F.3    Taboga, S.R.4
  • 6
    • 0030853418 scopus 로고    scopus 로고
    • Gonadal peptides as mediators of development and functional control of the testis: an integrated system with hormones and local environment
    • Gnessi L, Fabbri A, Spera G. Gonadal peptides as mediators of development and functional control of the testis: an integrated system with hormones and local environment. Endocr Ver 1997, 18:541-590.
    • (1997) Endocr Ver , vol.18 , pp. 541-590
    • Gnessi, L.1    Fabbri, A.2    Spera, G.3
  • 7
    • 0038732329 scopus 로고    scopus 로고
    • Effects of flutamide in the rat testis on the expression of occludin, an integral member of the tight junctions
    • Gye MC, Ohsako S. Effects of flutamide in the rat testis on the expression of occludin, an integral member of the tight junctions. Toxicol Lett 2003, 143:217-222.
    • (2003) Toxicol Lett , vol.143 , pp. 217-222
    • Gye, M.C.1    Ohsako, S.2
  • 8
    • 0034973368 scopus 로고    scopus 로고
    • Reel Lupron depot prevention of antispermatogenic/antifertility activity of the indenopyridine, CDB- 4022, in the rat
    • Hild AS, Meistrich ML, Blye RP, Reel JR. Reel Lupron depot prevention of antispermatogenic/antifertility activity of the indenopyridine, CDB- 4022, in the rat. Biol Reprod 2001, 65:165-172.
    • (2001) Biol Reprod , vol.65 , pp. 165-172
    • Hild, A.S.1    Meistrich, M.L.2    Blye, R.P.3    Reel, J.R.4
  • 10
    • 0019422190 scopus 로고
    • A histoquantitative study on the effects of castration on the rat ventral prostate lobe
    • Huttunen E, Romppnen T, Helminen HJ. A histoquantitative study on the effects of castration on the rat ventral prostate lobe. J Anat 1981, 3:357-370.
    • (1981) J Anat , vol.3 , pp. 357-370
    • Huttunen, E.1    Romppnen, T.2    Helminen, H.J.3
  • 11
    • 0014893015 scopus 로고
    • Testicular biopsy score count - a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males
    • Johnsen SG. Testicular biopsy score count - a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1970, 1:2-25.
    • (1970) Hormones , vol.1 , pp. 2-25
    • Johnsen, S.G.1
  • 12
    • 0027169382 scopus 로고
    • Effect of combination treatment with Zanoterone (WIN 49596), a steroidal androgen receptor antagonist, and Finasteride (MK-906) a steroidal 5 alpha-redutase inhibitor, on the prostate and testes of beagle dogs
    • Juniewicz PE, Hoekstra SJ, Lemp BM, Barbolt TA, Devin JA, Gauthier E, Frenette G, Dube JY. Effect of combination treatment with Zanoterone (WIN 49596), a steroidal androgen receptor antagonist, and Finasteride (MK-906) a steroidal 5 alpha-redutase inhibitor, on the prostate and testes of beagle dogs. Endocrinology 1993, 133:904-913.
    • (1993) Endocrinology , vol.133 , pp. 904-913
    • Juniewicz, P.E.1    Hoekstra, S.J.2    Lemp, B.M.3    Barbolt, T.A.4    Devin, J.A.5    Gauthier, E.6    Frenette, G.7    Dube, J.Y.8
  • 13
    • 0027408610 scopus 로고
    • Stage-dependent changes in spermatogenesis and Sertoli cells in relation to the onset of spermatogenic failure following withdrawal of testosterone
    • Kerr JB, Millar M, Maddocks S, Sharpe RM. Stage-dependent changes in spermatogenesis and Sertoli cells in relation to the onset of spermatogenic failure following withdrawal of testosterone. Anat Rec 1993, 235:547-559.
    • (1993) Anat Rec , vol.235 , pp. 547-559
    • Kerr, J.B.1    Millar, M.2    Maddocks, S.3    Sharpe, R.M.4
  • 14
    • 0035878820 scopus 로고    scopus 로고
    • Androgen blocks apoptosis of hormone-dependent prostate cancer cells
    • Kimura K, Markowski M, Bowen C, Gelmann EG. Androgen blocks apoptosis of hormone-dependent prostate cancer cells. Cancer Res 2001, 61:5611-5618.
    • (2001) Cancer Res , vol.61 , pp. 5611-5618
    • Kimura, K.1    Markowski, M.2    Bowen, C.3    Gelmann, E.G.4
  • 16
    • 0027422325 scopus 로고
    • Mechanism of action and pure antiandrogenic properties of flutamide
    • Labrie F. Mechanism of action and pure antiandrogenic properties of flutamide. Cancer 1993, 72:3816-3827.
    • (1993) Cancer , vol.72 , pp. 3816-3827
    • Labrie, F.1
  • 17
    • 0031040405 scopus 로고    scopus 로고
    • Protecting spermatogenesis from damage induced by doxorubicin using the luteinizing hormone-releasing hormone agonist leuprorelin
    • Manabe F, Hitoshi H, Akaza H. Protecting spermatogenesis from damage induced by doxorubicin using the luteinizing hormone-releasing hormone agonist leuprorelin. Cancer 1997, 79:1014-1021.
    • (1997) Cancer , vol.79 , pp. 1014-1021
    • Manabe, F.1    Hitoshi, H.2    Akaza, H.3
  • 18
    • 0023917872 scopus 로고
    • Characteristics of flutamide action on prostatic and testicular functions in rat
    • Marchetti B, Labrie F. Characteristics of flutamide action on prostatic and testicular functions in rat. J Steroid Biochem 1988, 29:691-698.
    • (1988) J Steroid Biochem , vol.29 , pp. 691-698
    • Marchetti, B.1    Labrie, F.2
  • 19
    • 0019956047 scopus 로고
    • Effects of cyproterone acetate and oestradiol benzoate on the rat testis
    • Mäusle E, Städtler F, Stenger D. Effects of cyproterone acetate and oestradiol benzoate on the rat testis. Pathol Res Pract 1982, 173:218-224.
    • (1982) Pathol Res Pract , vol.173 , pp. 218-224
    • Mäusle, E.1    Städtler, F.2    Stenger, D.3
  • 24
    • 0029097709 scopus 로고
    • Studies of spermatogenic damages induced by anti-cancer agent and antiandrogenic agents in rat testes
    • Nambu A, Kumamoto Y. Studies of spermatogenic damages induced by anti-cancer agent and antiandrogenic agents in rat testes. Nippon Hinyokika Gakkai Zasshi 1995, 86:1221-1230.
    • (1995) Nippon Hinyokika Gakkai Zasshi , vol.86 , pp. 1221-1230
    • Nambu, A.1    Kumamoto, Y.2
  • 25
    • 0022818061 scopus 로고
    • Pharmacology of antiandrogenics
    • Neumann F, Topert M. Pharmacology of antiandrogenics. J Steroid Biochem 1986, 25:885-895.
    • (1986) J Steroid Biochem , vol.25 , pp. 885-895
    • Neumann, F.1    Topert, M.2
  • 26
    • 0033659618 scopus 로고    scopus 로고
    • Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 5. Effects of repeated doses of Flutamide for 2 and 4 weeks
    • Okahara A, Nomura A, Tanioka H, Sakamoto H, Yamashita K, Ikuse T. Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 5. Effects of repeated doses of Flutamide for 2 and 4 weeks. J Toxicol Sci 2000, 25:63-70.
    • (2000) J Toxicol Sci , vol.25 , pp. 63-70
    • Okahara, A.1    Nomura, A.2    Tanioka, H.3    Sakamoto, H.4    Yamashita, K.5    Ikuse, T.6
  • 27
    • 0022437727 scopus 로고
    • Cell interactions during the seminiferous epithelial cycle
    • Parvinen M, Vihko KK, Toppari J. Cell interactions during the seminiferous epithelial cycle. Int Rev Cytol 1988, 104:115-151.
    • (1988) Int Rev Cytol , vol.104 , pp. 115-151
    • Parvinen, M.1    Vihko, K.K.2    Toppari, J.3
  • 28
    • 0036774169 scopus 로고    scopus 로고
    • Cancer progression in the kidney and prostate: vital roles of sphingolipids in chemotherapy
    • Radin NS. Cancer progression in the kidney and prostate: vital roles of sphingolipids in chemotherapy. Urology 2002, 60:562-568.
    • (2002) Urology , vol.60 , pp. 562-568
    • Radin, N.S.1
  • 29
    • 0018231608 scopus 로고
    • Hypothalamo-hypophyseal-gonadal system in male rats and Guinea pigs treated with the antiandrogen 4-nitro-3-trifluoromethylisobutyranilide
    • Reznikov AG, Demchenko VN, Varga SV, Bozhok YM. Hypothalamo-hypophyseal-gonadal system in male rats and Guinea pigs treated with the antiandrogen 4-nitro-3-trifluoromethylisobutyranilide. Endocrinologie 1978, 72:276-284.
    • (1978) Endocrinologie , vol.72 , pp. 276-284
    • Reznikov, A.G.1    Demchenko, V.N.2    Varga, S.V.3    Bozhok, Y.M.4
  • 30
    • 0034911348 scopus 로고    scopus 로고
    • Effects of androgen deprivation on the histology of adult chimpanzee testis
    • Smithwick EB, Young LG. Effects of androgen deprivation on the histology of adult chimpanzee testis. Tissue Cell 2001, 33:262-272.
    • (2001) Tissue Cell , vol.33 , pp. 262-272
    • Smithwick, E.B.1    Young, L.G.2
  • 31
    • 0015096164 scopus 로고
    • Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, acessory sexual glands and fertility in a long term study on rats
    • Steinbeck H, Mehring M, Neumann F. Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, acessory sexual glands and fertility in a long term study on rats. J Reprod Fertil 1971, 26:65-76.
    • (1971) J Reprod Fertil , vol.26 , pp. 65-76
    • Steinbeck, H.1    Mehring, M.2    Neumann, F.3
  • 32
    • 0020517373 scopus 로고
    • Endocrinological and histological changes induced by flutamide treatment on the hypothalamo-hypophyseal testicular axis of the adult male rat and their incidences on fertility
    • Viguier-Martinez MC, Hochereau de Reviers MT, Barenton B, Perreau C. Endocrinological and histological changes induced by flutamide treatment on the hypothalamo-hypophyseal testicular axis of the adult male rat and their incidences on fertility. Acta Endocrinol 1983, 104:246-252.
    • (1983) Acta Endocrinol , vol.104 , pp. 246-252
    • Viguier-Martinez, M.C.1    Hochereau de Reviers, M.T.2    Barenton, B.3    Perreau, C.4
  • 33
    • 0018147593 scopus 로고
    • Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice
    • Vojtísková M, Poláchová M, Viklický V, Khoda ME. Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice. Endokrinologie 1978, 71:135-142.
    • (1978) Endokrinologie , vol.71 , pp. 135-142
    • Vojtísková, M.1    Poláchová, M.2    Viklický, V.3    Khoda, M.E.4
  • 34
    • 0032569026 scopus 로고    scopus 로고
    • Inhibition of akt kinase by cel-permeable ceramide and its implications for ceramide-induced apoptosis
    • Zhou H, Summers SA, Birnbaum MJ, Pittman RN. Inhibition of akt kinase by cel-permeable ceramide and its implications for ceramide-induced apoptosis. J Biol Chem 1998, 273:16568-16575.
    • (1998) J Biol Chem , vol.273 , pp. 16568-16575
    • Zhou, H.1    Summers, S.A.2    Birnbaum, M.J.3    Pittman, R.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.