Nasal administration of ciprofloxacin HCL loaded chitosan microspheres: In vitro and in vivo evaluation;Siprofloksazin HCl yüklü kitozan mikrokürelerinin nazal verilişi: In vitro ve in vivo deǧerlendirme

Acta Pharmaceutica Sciencia

Volumn 52, Issue 1, 2010, Pages 5-18

  Gürcan, Duygu ^a   Okyar, Alper ^a   Özbek, Berna ^a   Baktir, Gül ^a   Gerçeker, Alev ^a   Özsoy, Yildiz ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Chitosan; Ciprofloxacin hydrochloride; Microsphere; Nasal drug delivery; Spray drying method

Indexed keywords

CHITOSAN; CIPROFLOXACIN; GLUTARALDEHYDE; MICROSPHERE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHEMICAL INTERACTION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; ENCAPSULATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; MORPHOLOGY; NONHUMAN; PARTICLE SIZE; RAT; SPRAY DRYING; SUSPENSION; SUSTAINED RELEASE FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 77954191349     PISSN: 13072080     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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