In vitro and in vivo antimalarial evaluation of semi-synthetic derivatives of gomphostenin

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 14, 2010, Pages 4233-4236

  Sathe, Manisha ^a   Kaushik, M P ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

Antimalarials; Clerodane; Gomphostemma niveum; In vitro; In vivo; Semi synthesis

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; GOMPHOSTENIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLASMODIUM BERGHEI INFECTION; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; DITERPENES; DRUG EVALUATION, PRECLINICAL; MICE; PLASMODIUM FALCIPARUM;

GOMPHOSTEMMA; MUS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 77954142750     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.05.035     Document Type: Article

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