The IFN-γ allele is correlated to moderate-to-severe acute graft-versus-host disease after allogeneic stem cell transplant

Experimental and Clinical Transplantation

Volumn 8, Issue 2, 2010, Pages

  Karimi, Mohammad Hossein ^a   Daneshmandi, Saeed ^b   Pourfathollah, Ali Akbar ^b   Geramizadeh, Bita ^a   Ramzi, Mani ^c   Yaghobi, Ramin ^a   Ebadi, Padideh ^d  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TARBIAT MODARES UNIVERSITY   (Iran)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Bone marrow transplant; Cytokine polymorphism

Indexed keywords

ADENINE; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTOSINE; GAMMA INTERFERON; GUANINE; HLA ANTIGEN; INTERLEUKIN 4; INTERLEUKIN 6; METHOTREXATE; RESTRICTION ENDONUCLEASE; THYMINE; THYMOCYTE ANTIBODY; TRANSFORMING GROWTH FACTOR BETA;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ALLELE; ALLOGENEIC STEM CELL TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FANCONI ANEMIA; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; GRAFT REJECTION; HLA MATCHING; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PREDICTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

EID: 77954137171     PISSN: 13040855     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Cavet J, Dickinson AM, Norden J, Taylor PR, Jackson GH, Middleton PG. Interferon-gamma and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation. Blood. 2001;98(5):1594-1600.
2. Hägglund H, Boström L, Remberger M, Ljungman P, Nilsson B, Ringdén O. Risk factors for acute graft-versus-host disease in 291 consecutive HLA-identical bone marrow transplant recipients. Bone Marrow Transplant. 1995;16(6):747-753.
3. Hattori H, Matsuzaki A, Suminoe A, et al. Polymorphisms of transforming growth factor-beta1 and transforming growth factor-beta1 type II receptor genes are associated with acute graft-versus-host disease in children with HLA-matched sibling bone marrow transplantation. Bone Marrow Transplant. 2002;30(10):665-671.
4. Daser A, Mitchison H, Mitchison A, Müller B. Non-classical-MHC genetics of immunological disease in man and mouse. The key role of pro-inflammatory cytokine genes. Cytokine. 1996;8(8):593-597.
5. Middleton PG, Taylor PR, Jackson G, Proctor SJ, Dickinson AM. Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants. Blood. 1998;92(10):3943-3948.
6. Krenger W, Hill GR, Ferrara JL. Cytokine cascades in acute graft-versus-host disease. Transplantation. 1997;64(4):553-558.
7. Körholz D, Kunst D, Hempel L, et al. Decreased interleukin 10 and increased interferon-gamma production in patients with chronic graft-versus-host disease after allogeneic bone marrow transplantation. Bone Marrow Transplant. 1997;19(7):691-695.
8. Theobald M. Allorecognition and graft-versus-host disease. Bone Marrow Transplant. 1995;15(4):489-498.
9. Akalin E, Murphy B. Gene polymorphisms and transplantation. Curr Opin Immunol. 2001;13(5):572-576.
10. Marshall SE, Welsh KI. The role of cytokine polymorphisms in rejection after solid organ transplantation. Genes Immun. 2001;2(6):297-303.
11. Fishman D, Faulds G, Jeffery R, et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest. 1998;102(7):1369-1376.
12. Arkwright PD, Chase JM, Babbage S, Pravica V, David TJ, Hutchinson IV. Atopic dermatitis is associated with a low-producer transforming growth factor beta(1) cytokine genotype. J Allergy Clin Immunol. 2001;108(2):281-284.
13. Kamali-Sarvestani E, Zolghadri J, Gharesi-Fard B, Sarvari J. Cytokine gene polymorphisms and susceptibility to recurrent pregnancy loss in Iranian women. J Reprod Immunol. 2005;65(2):171-178.
14. Ferrara JL, Deeg HJ. Graft-versus-host disease. N Engl J Med. 1991;324(10):667-674.
15. Hägglund H, Boström L, Remberger M, Ljungman P, Nilsson B, Ringdén O. Risk factors for acute graft-versus-host disease in 291 consecutive HLA-identical bone marrow transplant recipients. Bone Marrow Transplant. 1995;16(6):747-753.
16. Dickinson AM, Middleton PG, Rocha V, Gluckman E, Holler E; Eurobank members. Genetic polymorphisms predicting the outcome of bone marrow transplants. Br J Haematol. 2004;127(5):479-490.
17. Cavet J, Middleton PG, Segall M, Noreen H, Davies SM, Dickinson AM. Recipient tumor necrosis factor-alpha and interleukin-10 gene polymorphisms associate with early mortality and acute graft-versus-host disease severity in HLA-matched sibling bone marrow transplants. Blood. 1999;94(11):3941-3946.
18. Takahashi H, Furukawa T, Hashimoto S, et al. Contribution of TNF-alpha and IL-10 gene polymorphisms to graft-versus-host disease following allo-hematopoietic stem cell transplantation. Bone Marrow Transplant. 2000;26(12):1317-1323.
19. Socié G, Loiseau P, Tamouza R, et al. Both genetic and clinical factors predict the development of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Transplantation. 2001;72(4):699-706.
20. Krenger W, Ferrara JL. Graft-versus-host disease and the Th1/Th2 paradigm. Immunol Res. 1996;15(1):50-73.
21. Krenger W, Cooke KR, Crawford JM, et al. Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease. Transplantation. 1996;62(9):1278-1285.
22. Blazar BR, Taylor PA, Smith S, Vallera DA. Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts. Blood. 1995;85(3):842-851.
23. Murphy WJ, Welniak LA, Taub DD, et al. Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J Clin Invest. 1998;102(9):1742-1728.
24. Ushiyama C, Hirano T, Miyajima H, Okumura K, Ovary Z, Hashimoto H. Anti-IL-4 antibody prevents graft-versus-host disease in mice after bone marrow transplantation. The IgE allotype is an important marker of graft-versus-host disease. J Immunol. 1995;154(6):2687-2696.
25. Symington FW, Symington BE, Liu PY, Viguet H, Santhanam U, Sehgal PB. The relationship of serum IL-6 levels to acute graft-versus-host disease and hepatorenal disease after human bone marrow transplantation. Transplantation. 1992;54(3):457-462.
26. Abdallah AN, Boiron JM, Attia Y, Cassaigne A, Reiffers J, Iron A. Plasma cytokines in graft vs host disease and complications following bone marrow transplantation. Hematol Cell Ther. 1997;39(1):27-32.